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Protein

Regulatory protein CysR

Gene

cysR

Organism
Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probably regulates the expression of genes from the sulfate permease complex.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi156 – 175H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processStress response, Sulfate transport, Transcription, Transcription regulation, Transport

Enzyme and pathway databases

BioCyciSYNEL:SYNPCC7942_1684-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Regulatory protein CysR
Gene namesi
Name:cysR
Ordered Locus Names:Synpcc7942_1684
OrganismiSynechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)
Taxonomic identifieri1140 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000002717 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001001531 – 206Regulatory protein CysRAdd BLAST206

Expressioni

Inductioni

By sulfur deprivation.

Interactioni

Protein-protein interaction databases

STRINGi1140.Synpcc7942_1684.

Structurei

3D structure databases

ProteinModelPortaliP27369.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini120 – 196HTH crp-typePROSITE-ProRule annotationAdd BLAST77

Phylogenomic databases

eggNOGiENOG4108W3Y. Bacteria.
COG0664. LUCA.
HOGENOMiHOG000035273.
OrthoDBiPOG090F00QU.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiView protein in InterPro
IPR018490. cNMP-bd-like.
IPR012318. HTH_CRP.
IPR014710. RmlC-like_jellyroll.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF13545. HTH_Crp_2. 1 hit.
SMARTiView protein in SMART
SM00419. HTH_CRP. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF51206. SSF51206. 1 hit.
PROSITEiView protein in PROSITE
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P27369-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVREPASTLL PPTSPATPAP HRLLIGRRGM VPTGANVIWK IQSGLVRSST
60 70 80 90 100
WGEEGDMISL GLWGPGDLIG RPLSCLDPYE LECLTAVEVV AVSDPALESH
110 120 130 140 150
ESLVRSLRYT ERLLSITRLR RAEAKLASLL GWIGERFGQP GATGWEIDLR
160 170 180 190 200
RIPLTHQVIA ELSGSTRVTT TRLLGEFRQA GRIHRRDRAL IVRYPETLYP

PARLSA
Length:206
Mass (Da):22,760
Last modified:August 1, 1992 - v1
Checksum:i21B57BE397EA7E44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M65247 Genomic DNA. Translation: AAA73046.1.
CP000100 Genomic DNA. Translation: ABB57714.1.
RefSeqiWP_011244716.1. NC_007604.1.

Genome annotation databases

EnsemblBacteriaiABB57714; ABB57714; Synpcc7942_1684.
KEGGisyf:Synpcc7942_1684.
PATRICi23788771. VBISynElo51371_1909.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M65247 Genomic DNA. Translation: AAA73046.1.
CP000100 Genomic DNA. Translation: ABB57714.1.
RefSeqiWP_011244716.1. NC_007604.1.

3D structure databases

ProteinModelPortaliP27369.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1140.Synpcc7942_1684.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB57714; ABB57714; Synpcc7942_1684.
KEGGisyf:Synpcc7942_1684.
PATRICi23788771. VBISynElo51371_1909.

Phylogenomic databases

eggNOGiENOG4108W3Y. Bacteria.
COG0664. LUCA.
HOGENOMiHOG000035273.
OrthoDBiPOG090F00QU.

Enzyme and pathway databases

BioCyciSYNEL:SYNPCC7942_1684-MONOMER.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiView protein in InterPro
IPR018490. cNMP-bd-like.
IPR012318. HTH_CRP.
IPR014710. RmlC-like_jellyroll.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF13545. HTH_Crp_2. 1 hit.
SMARTiView protein in SMART
SM00419. HTH_CRP. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF51206. SSF51206. 1 hit.
PROSITEiView protein in PROSITE
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCYSR_SYNE7
AccessioniPrimary (citable) accession number: P27369
Secondary accession number(s): Q31MK5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: February 15, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.