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Protein

Nucleoprotein

Gene

N

Organism
Hazara virus (isolate JC280)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Ligandi

RNA-binding, Viral nucleoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoprotein
Alternative name(s):
Nucleocapsid protein
Short name:
Protein N
Gene namesi
Name:N
OrganismiHazara virus (isolate JC280)
Taxonomic identifieri11597 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA negative-strand virusesBunyaviridaeNairovirus
Virus hostiIxodes [TaxID: 6944]

Subcellular locationi

  • Virion

  • Note: Internal protein of virus particle.

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 485485NucleoproteinPRO_0000222008Add
BLAST

Structurei

Secondary structure

1
485
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi10 – 2415Combined sources
Beta strandi29 – 335Combined sources
Helixi44 – 529Combined sources
Helixi56 – 7116Combined sources
Helixi77 – 848Combined sources
Helixi86 – 9914Combined sources
Helixi103 – 1097Combined sources
Helixi112 – 1154Combined sources
Helixi122 – 13918Combined sources
Helixi145 – 1473Combined sources
Beta strandi156 – 1594Combined sources
Turni162 – 1643Combined sources
Helixi165 – 18319Combined sources
Helixi199 – 20810Combined sources
Helixi212 – 2165Combined sources
Beta strandi228 – 2325Combined sources
Helixi233 – 24513Combined sources
Helixi248 – 26619Combined sources
Helixi268 – 2703Combined sources
Helixi273 – 29624Combined sources
Helixi298 – 3036Combined sources
Helixi309 – 31911Combined sources
Turni324 – 3263Combined sources
Helixi327 – 33711Combined sources
Helixi344 – 35310Combined sources
Beta strandi354 – 3563Combined sources
Helixi357 – 3648Combined sources
Beta strandi368 – 3703Combined sources
Helixi375 – 3773Combined sources
Helixi388 – 3958Combined sources
Helixi403 – 4086Combined sources
Helixi413 – 4186Combined sources
Helixi423 – 4253Combined sources
Helixi428 – 44316Combined sources
Turni446 – 4483Combined sources
Beta strandi449 – 4513Combined sources
Helixi453 – 46210Combined sources
Beta strandi483 – 4853Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
5A97X-ray2.70A/B/C/D1-485[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR003486. Nairo_nucleocap.
[Graphical view]
PfamiPF02477. Nairo_nucleo. 1 hit.
[Graphical view]
PIRSFiPIRSF003950. N_NairoV. 1 hit.

Sequencei

Sequence statusi: Complete.

P27318-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENKIVASTK EEFNTWYKQF AEKHKLNNKY TESASFCAEI PQLDTYKYKM
60 70 80 90 100
ELASTDNERD AIYSSALIEA TRFCAPIMEC AWASCTGTVK RGLEWFDKNK
110 120 130 140 150
DSDTVKVWDA NYQKLRTETP PAEALLAYQK AALNWRKDVG FSIGEYTSIL
160 170 180 190 200
KKAVAAEYKV PGTVINNIKE MLSDMIRRRN RIINGGSDDA PKRGPVGREH
210 220 230 240 250
LDWCREFASG KFLNAFNPPW GEINKAGKSG YPLLATGLAK LVELEGKDVM
260 270 280 290 300
DKAKASIAQL EGWVKENKDQ VDQDKAEDLL KGVRESYKTA LALAKLSNAF
310 320 330 340 350
RAQGAQIDTV FSSYYWPWKA GVTPVTFPSV SQFLFELGKN PKGQKKMQKA
360 370 380 390 400
LINTPLKWGK RLIELFADND FTENRIYMHP CVLTSGRMSE LGISFGAVPV
410 420 430 440 450
TSPDDAAQGS GHTKAVLNYK TKTEVGNPCA CIISSLFEIQ KAGYDIESMD
460 470 480
IVASEHLLHQ SLVGKRSPFQ NAYLIKGNAT NINII
Length:485
Mass (Da):54,186
Last modified:August 1, 1992 - v1
Checksum:i6053892EB6DB05EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M86624 Genomic RNA. Translation: AAA43842.1.
PIRiA42990. VHVUHJ.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M86624 Genomic RNA. Translation: AAA43842.1.
PIRiA42990. VHVUHJ.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
5A97X-ray2.70A/B/C/D1-485[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR003486. Nairo_nucleocap.
[Graphical view]
PfamiPF02477. Nairo_nucleo. 1 hit.
[Graphical view]
PIRSFiPIRSF003950. N_NairoV. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparison of the S RNA segments and nucleoprotein sequences of Crimean-Congo hemorrhagic fever, Hazara, and Dugbe viruses."
    Marriott A.C., Nuttall P.A.
    Virology 189:795-799(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiNCAP_HAZVJ
AccessioniPrimary (citable) accession number: P27318
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: April 13, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.