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Protein

Nucleoprotein

Gene

N

Organism
Crimean-Congo hemorrhagic fever virus (isolate C68031) (CCHFV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Ligandi

RNA-binding, Viral nucleoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoprotein
Alternative name(s):
Nucleocapsid protein
Short name:
Protein N
Gene namesi
Name:N
OrganismiCrimean-Congo hemorrhagic fever virus (isolate C68031) (CCHFV)
Taxonomic identifieri11594 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaeNairovirus
Virus hostiBos taurus (Bovine) [TaxID: 9913]
Capra hircus (Goat) [TaxID: 9925]
Homo sapiens (Human) [TaxID: 9606]
Hyalomma [TaxID: 34625]
Ovis aries (Sheep) [TaxID: 9940]
Rhipicephalus microplus (Cattle tick) (Boophilus microplus) [TaxID: 6941]

Subcellular locationi

  • Virion

  • Note: Internal protein of virus particle.

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 482482NucleoproteinPRO_0000222006Add
BLAST

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR003486. Nairo_nucleocap.
[Graphical view]
PfamiPF02477. Nairo_nucleo. 1 hit.
[Graphical view]
PIRSFiPIRSF003950. N_NairoV. 1 hit.

Sequencei

Sequence statusi: Complete.

P27317-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENKIEVNNK DEMNKWFEEF KKGNGLVDTF TNPYSFCESV PNLERFVFQM
60 70 80 90 100
ASATDDAQKD SIYASALVEA TKFCAPIYEC AWVSSTGIVK KGLEWFEKNA
110 120 130 140 150
GTIKSWDESY IELKVEVPKI EQLANYQQAA LKWRKDIGFR VNANTAALSH
160 170 180 190 200
KVLAEYKVPG EIVMSVKEML SDMIRRRNLI LNRGGDENPR GPVSREHVEW
210 220 230 240 250
CREFVKGKYI MAFNPPWGDI NKSGRSGIAL VATGLAKLAE TEGKGVFDEA
260 270 280 290 300
KKTVEALNGY LDKHKDEVDK ASADNMITNL LKHIAKAQEL YKNSSALRAQ
310 320 330 340 350
GAQIDTAFSS YYWLYKAGVT PETFPTVSQF LFELGKQPRG TKKMKKALLS
360 370 380 390 400
TPMKWGKKLY ELFADDSFQQ NRIYMHPAVL TAGRISEMGV CFGTIPVANP
410 420 430 440 450
DDAAQGSGHT KSILNLRTNT ETNNPCAKTI VKLFEIQKTG FNIQDMDIVA
460 470 480
SEHLLHQSLV GKQSPFQNAY NVKGNATSAN II
Length:482
Mass (Da):53,966
Last modified:August 1, 1992 - v1
Checksum:i171F8D9438F00FA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M86625 Genomic RNA. Translation: AAA42888.1.
PIRiB42990. VHVUCH.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M86625 Genomic RNA. Translation: AAA42888.1.
PIRiB42990. VHVUCH.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR003486. Nairo_nucleocap.
[Graphical view]
PfamiPF02477. Nairo_nucleo. 1 hit.
[Graphical view]
PIRSFiPIRSF003950. N_NairoV. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparison of the S RNA segments and nucleoprotein sequences of Crimean-Congo hemorrhagic fever, Hazara, and Dugbe viruses."
    Marriott A.C., Nuttall P.A.
    Virology 189:795-799(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiNCAP_CCHFV
AccessioniPrimary (citable) accession number: P27317
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: April 29, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.