P27313 (NCAP_PUUMS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nucleoprotein

Alternative name(s):
Nucleocapsid protein
Short name=Protein N

Gene names

Name:

N

Organism

Puumala virus (strain Sotkamo/V-2969/81) [Complete proteome]

Taxonomic identifier

39002 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Bunyaviridae › Hantavirus › Puumala virus

Virus host

Homo sapiens (Human) [TaxID: 9606]
Myodes glareolus (Bank vole) (Clethrionomys glareolus) [TaxID: 447135]

Protein attributes

Sequence length	433 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Virion. Note: Internal protein of virus particle.
Sequence similarities	Belongs to the hantavirus nucleocapsid protein family.

Ontologies

Keywords
Cellular component	Virion
Ligand	RNA-binding Viral nucleoprotein
Molecular function	Ribonucleoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	ribonucleoprotein complex Inferred from electronic annotation. Source: UniProtKB-KW viral nucleocapsid Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 433	433	Nucleoprotein		PRO_0000222016

Sequences

	Sequence		Length	Mass (Da)
	P27313 [UniParc]. Last modified August 1, 1992. Version 1. Checksum: 27D98B3F65BA026E	FASTA	433	49,452
	10 20 30 40 50 60 MSDLTDIQED ITRHEQQLIV ARQKLKDAER AVEVDPDDVN KNTLQARQQT VSALEDKLAD 70 80 90 100 110 120 YKRRMADAVS RKKMDTKPTD PTGIEPDDHL KERSSLRYGN VLDVNAIDIE EPSGQTADWY 130 140 150 160 170 180 TIGVYVIGFT LPIILKALYM LSTRGRQTVK ENKGTRIRFK DDTSFEDING IRRPKHLYVS 190 200 210 220 230 240 MPTAQSTMKA EELTPGRFRT IVCGLFPTQI QVRNIMSPVM GVIGFSFFVK DWSERIREFM 250 260 270 280 290 300 EKECPFIKPE VKPGTPAQEI EMLKRNKIYF MQRQDVLDKN HVADIDKLID YAASGDPTSP 310 320 330 340 350 360 DNIDSPNAPW VFACAPDRCP PTCIYVAGMA ELGAFFSILQ DMRNTIMASK TVGTAEEKLK 370 380 390 400 410 420 KKSSFYQSYL RRTQSMGIQL DQRIILLFML EWGKEMVDHF HLGDDMDPEL RGLAQALIDQ 430 KVKEISNQEP LKI

References

[1]

"Cloning and sequencing of Puumala virus Sotkamo strain S and M RNA segments: evidence for strain variation in hantaviruses and expression of the nucleocapsid protein." Vapalahti O.P., Kallio-Kokko H., Salonen E.M., Brummer-Korvenkontio M., Vaheri A. J. Gen. Virol. 73:829-838(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	X61035 Genomic RNA. Translation: CAA43370.1.
PIR	JQ1605.
RefSeq	NP_941984.1. NC_005224.1.
3D structure databases
ProteinModelPortal	P27313.
SMR	P27313. Positions 1-74.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2943083.
Family and domain databases
InterPro	IPR002214. Hanta_nucleocap. [Graphical view]
Pfam	PF00846. Hanta_nucleocap. 1 hit. [Graphical view]
PIRSF	PIRSF003949. N_HantaV. 1 hit.
ProDom	PD001501. Hanta_nucleocap. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

NCAP_PUUMS

Accession

Primary (citable) accession number: P27313

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	August 1, 1992
Last modified:	April 3, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program