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P27313

- NCAP_PUUMS

UniProt

P27313 - NCAP_PUUMS

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Protein

Nucleoprotein

Gene

N

Organism
Puumala virus (strain Sotkamo/V-2969/81)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication (By similarity).By similarity

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Ligandi

RNA-binding, Viral nucleoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoprotein
Alternative name(s):
Nucleocapsid protein
Short name:
Protein N
Gene namesi
Name:N
OrganismiPuumala virus (strain Sotkamo/V-2969/81)
Taxonomic identifieri39002 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaeHantavirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Myodes glareolus (Bank vole) (Clethrionomys glareolus) [TaxID: 447135]
ProteomesiUP000008482: Genome

Subcellular locationi

Virion
Note: Internal protein of virus particle.

GO - Cellular componenti

  1. helical viral capsid Source: UniProtKB-KW
  2. ribonucleoprotein complex Source: UniProtKB-KW
  3. viral nucleocapsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 433433NucleoproteinPRO_0000222016Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP27313.
SMRiP27313. Positions 1-74.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR002214. Hanta_nucleocap.
[Graphical view]
PfamiPF00846. Hanta_nucleocap. 1 hit.
[Graphical view]
PIRSFiPIRSF003949. N_HantaV. 1 hit.
ProDomiPD001501. Hanta_nucleocap. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

P27313 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDLTDIQED ITRHEQQLIV ARQKLKDAER AVEVDPDDVN KNTLQARQQT
60 70 80 90 100
VSALEDKLAD YKRRMADAVS RKKMDTKPTD PTGIEPDDHL KERSSLRYGN
110 120 130 140 150
VLDVNAIDIE EPSGQTADWY TIGVYVIGFT LPIILKALYM LSTRGRQTVK
160 170 180 190 200
ENKGTRIRFK DDTSFEDING IRRPKHLYVS MPTAQSTMKA EELTPGRFRT
210 220 230 240 250
IVCGLFPTQI QVRNIMSPVM GVIGFSFFVK DWSERIREFM EKECPFIKPE
260 270 280 290 300
VKPGTPAQEI EMLKRNKIYF MQRQDVLDKN HVADIDKLID YAASGDPTSP
310 320 330 340 350
DNIDSPNAPW VFACAPDRCP PTCIYVAGMA ELGAFFSILQ DMRNTIMASK
360 370 380 390 400
TVGTAEEKLK KKSSFYQSYL RRTQSMGIQL DQRIILLFML EWGKEMVDHF
410 420 430
HLGDDMDPEL RGLAQALIDQ KVKEISNQEP LKI
Length:433
Mass (Da):49,452
Last modified:August 1, 1992 - v1
Checksum:i27D98B3F65BA026E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X61035 Genomic RNA. Translation: CAA43370.1.
HE801633 Genomic RNA. Translation: CCH22846.1.
PIRiJQ1605.
RefSeqiNP_941984.1. NC_005224.1.

Genome annotation databases

GeneIDi2943083.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X61035 Genomic RNA. Translation: CAA43370.1 .
HE801633 Genomic RNA. Translation: CCH22846.1 .
PIRi JQ1605.
RefSeqi NP_941984.1. NC_005224.1.

3D structure databases

ProteinModelPortali P27313.
SMRi P27313. Positions 1-74.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2943083.

Family and domain databases

InterProi IPR002214. Hanta_nucleocap.
[Graphical view ]
Pfami PF00846. Hanta_nucleocap. 1 hit.
[Graphical view ]
PIRSFi PIRSF003949. N_HantaV. 1 hit.
ProDomi PD001501. Hanta_nucleocap. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and sequencing of Puumala virus Sotkamo strain S and M RNA segments: evidence for strain variation in hantaviruses and expression of the nucleocapsid protein."
    Vapalahti O.P., Kallio-Kokko H., Salonen E.M., Brummer-Korvenkontio M., Vaheri A.
    J. Gen. Virol. 73:829-838(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. "Resequencing of the Puumala virus strain Sotkamo from the WHO Arbovirus collection."
    Kurolt I.C., Paessler S., Markotic A.
    Virus Genes 45:389-392(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    Strain: Isolate Sotkamo 2009/WHO Arbovirus collection.

Entry informationi

Entry nameiNCAP_PUUMS
AccessioniPrimary (citable) accession number: P27313
Secondary accession number(s): I4EPA2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: October 1, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3