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P27313

- NCAP_PUUMS

UniProt

P27313 - NCAP_PUUMS

Protein

Nucleoprotein

Gene

N

Organism
Puumala virus (strain Sotkamo/V-2969/81)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (01 Aug 1992)
      Previous versions | rss
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    Functioni

    Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication By similarity.By similarity

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Ribonucleoprotein

    Keywords - Ligandi

    RNA-binding, Viral nucleoprotein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nucleoprotein
    Alternative name(s):
    Nucleocapsid protein
    Short name:
    Protein N
    Gene namesi
    Name:N
    OrganismiPuumala virus (strain Sotkamo/V-2969/81)
    Taxonomic identifieri39002 [NCBI]
    Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaeHantavirus
    Virus hostiHomo sapiens (Human) [TaxID: 9606]
    Myodes glareolus (Bank vole) (Clethrionomys glareolus) [TaxID: 447135]
    ProteomesiUP000008482: Genome

    Subcellular locationi

    Virion
    Note: Internal protein of virus particle.

    GO - Cellular componenti

    1. helical viral capsid Source: UniProtKB-KW
    2. ribonucleoprotein complex Source: UniProtKB-KW
    3. viral nucleocapsid Source: UniProtKB-KW

    Keywords - Cellular componenti

    Capsid protein, Helical capsid protein, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 433433NucleoproteinPRO_0000222016Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP27313.
    SMRiP27313. Positions 1-74.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR002214. Hanta_nucleocap.
    [Graphical view]
    PfamiPF00846. Hanta_nucleocap. 1 hit.
    [Graphical view]
    PIRSFiPIRSF003949. N_HantaV. 1 hit.
    ProDomiPD001501. Hanta_nucleocap. 1 hit.
    [Graphical view] [Entries sharing at least one domain]

    Sequencei

    Sequence statusi: Complete.

    P27313-1 [UniParc]FASTAAdd to Basket

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    MSDLTDIQED ITRHEQQLIV ARQKLKDAER AVEVDPDDVN KNTLQARQQT    50
    VSALEDKLAD YKRRMADAVS RKKMDTKPTD PTGIEPDDHL KERSSLRYGN 100
    VLDVNAIDIE EPSGQTADWY TIGVYVIGFT LPIILKALYM LSTRGRQTVK 150
    ENKGTRIRFK DDTSFEDING IRRPKHLYVS MPTAQSTMKA EELTPGRFRT 200
    IVCGLFPTQI QVRNIMSPVM GVIGFSFFVK DWSERIREFM EKECPFIKPE 250
    VKPGTPAQEI EMLKRNKIYF MQRQDVLDKN HVADIDKLID YAASGDPTSP 300
    DNIDSPNAPW VFACAPDRCP PTCIYVAGMA ELGAFFSILQ DMRNTIMASK 350
    TVGTAEEKLK KKSSFYQSYL RRTQSMGIQL DQRIILLFML EWGKEMVDHF 400
    HLGDDMDPEL RGLAQALIDQ KVKEISNQEP LKI 433
    Length:433
    Mass (Da):49,452
    Last modified:August 1, 1992 - v1
    Checksum:i27D98B3F65BA026E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X61035 Genomic RNA. Translation: CAA43370.1.
    HE801633 Genomic RNA. Translation: CCH22846.1.
    PIRiJQ1605.
    RefSeqiNP_941984.1. NC_005224.1.

    Genome annotation databases

    GeneIDi2943083.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X61035 Genomic RNA. Translation: CAA43370.1 .
    HE801633 Genomic RNA. Translation: CCH22846.1 .
    PIRi JQ1605.
    RefSeqi NP_941984.1. NC_005224.1.

    3D structure databases

    ProteinModelPortali P27313.
    SMRi P27313. Positions 1-74.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2943083.

    Family and domain databases

    InterProi IPR002214. Hanta_nucleocap.
    [Graphical view ]
    Pfami PF00846. Hanta_nucleocap. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF003949. N_HantaV. 1 hit.
    ProDomi PD001501. Hanta_nucleocap. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and sequencing of Puumala virus Sotkamo strain S and M RNA segments: evidence for strain variation in hantaviruses and expression of the nucleocapsid protein."
      Vapalahti O.P., Kallio-Kokko H., Salonen E.M., Brummer-Korvenkontio M., Vaheri A.
      J. Gen. Virol. 73:829-838(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    2. "Resequencing of the Puumala virus strain Sotkamo from the WHO Arbovirus collection."
      Kurolt I.C., Paessler S., Markotic A.
      Virus Genes 45:389-392(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
      Strain: Isolate Sotkamo 2009/WHO Arbovirus collection.

    Entry informationi

    Entry nameiNCAP_PUUMS
    AccessioniPrimary (citable) accession number: P27313
    Secondary accession number(s): I4EPA2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1992
    Last sequence update: August 1, 1992
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3