Reviewed, UniProtKB/Swiss-Prot P27247 (PLSX_ECOLI)

Names and origin

Protein names

Recommended name:
    Fatty acid/phospholipid synthesis protein plsX

Gene names

Name:	plsX
Ordered Locus Names:	b1090, JW5156

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	356 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Probably involved in fatty acid or phospholipid synthesis. HAMAP MF_00019
Sequence similarities	Belongs to the plsX family.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis Phospholipid biosynthesis
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP phospholipid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalytic activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 356	356	Fatty acid/phospholipid synthesis protein plsX HAMAP MF_00019		PRO_0000189875

Sequences

	Sequence		Length	Mass (Da)
	P27247-1 [UniParc]. Last modified May 30, 2000. Version 2. Checksum: 89C6C64C57184DF4	FASTA	356	38,214
	10 20 30 40 50 60 MTRLTLALDV MGGDFGPSVT VPAALQALNS NSQLTLLLVG NSDAITPLLA KADFEQRSRL 70 80 90 100 110 120 QIIPAQSVIA SDARPSQAIR ASRGSSMRVA LELVKEGRAQ ACVSAGNTGA LMGLAKLLLK 130 140 150 160 170 180 PLEGIERPAL VTVLPHQQKG KTVVLDLGAN VDCDSTMLVQ FAIMGSVLAE EVVEIPNPRV 190 200 210 220 230 240 ALLNIGEEEV KGLDSIRDAS AVLKTIPSIN YIGYLEANEL LTGKTDVLVC DGFTGNVTLK 250 260 270 280 290 300 TMEGVVRMFL SLLKSQGEGK KRSWWLLLLK RWLQKSLTRR FSHLNPDQYN GACLLGLRGT 310 320 330 340 350 VIKSHGAANQ RAFAVAIEQA VQAVQRQVPQ RIAARLESVY PAGFELLDGG KSGTLR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Physical locations of genes in the rne (ams)-rpmF-plsX-fab region of the Escherichia coli K-12 chromosome." Oh W., Larson T.J. J. Bacteriol. 174:7873-7874(1992) [PubMed: 1447160] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T. DNA Res. 3:137-155(1996) [PubMed: 8905232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-30. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBLGenBankDDBJ	M96793 Genomic DNA. Translation: AAB59064.1. Different initiation. U00096 Genomic DNA. Translation: AAC74174.1. Different initiation. AP009048 Genomic DNA. Translation: BAA35898.2.
PIR	G64852.
RefSeq	AP_001716.1. NP_415608.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	P27247.
Genome annotation databases
GeneID	946165.
GenomeReviews	Gene locus JW5156 in contig AP009048_GR. Gene locus b1090 in contig U00096_GR.
KEGG	ecj:JW5156. eco:b1090.
Organism-specific databases
EchoBASE	EB1407.
EcoGene	EG11437. plsX.
CMR	Search...
Phylogenomic databases
HOGENOM	P27247.
OMA	EGFSGNI.
Enzyme and pathway databases
BioCyc	EcoCyc:EG11437-MON.
Gene expression databases
Genevestigator	P27247.
Family and domain databases
HAMAP	MF_00019. [Tree]
InterPro	IPR003664. FA_synthesis. IPR012281. PlsX_like. [Graphical view]
Pfam	PF02504. FA_synthesis. 1 hit. [Graphical view]
PIRSF	PIRSF002465. Phsphlp_syn_PlsX. 1 hit.
ProDom	PD006974. FA_synthesis. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00182. plsX. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PLSX_ECOLI

Accession

Primary (citable) accession number: P27247

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	May 30, 2000
Last modified:	November 3, 2009
This is version 65 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)