Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P27242

- WAAU_ECOLI

UniProt

P27242 - WAAU_ECOLI

Protein

Lipopolysaccharide 1,2-N-acetylglucosaminetransferase

Gene

waaU

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 3 out of 5- Protein predictedi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 108 (01 Oct 2014)
      Sequence version 2 (01 Oct 1994)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS.

    Catalytic activityi

    UDP-N-acetyl-alpha-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-alpha-D-glucosaminyllipopolysaccharide.

    Pathwayi

    GO - Molecular functioni

    1. lipopolysaccharide N-acetylglucosaminyltransferase activity Source: UniProtKB-EC
    2. transferase activity, transferring glycosyl groups Source: EcoCyc

    GO - Biological processi

    1. lipopolysaccharide core region biosynthetic process Source: EcoCyc

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipopolysaccharide biosynthesis

    Enzyme and pathway databases

    BioCyciEcoCyc:EG11423-MONOMER.
    ECOL316407:JW3598-MONOMER.
    MetaCyc:EG11423-MONOMER.
    UniPathwayiUPA00958.

    Protein family/group databases

    CAZyiGT9. Glycosyltransferase Family 9.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipopolysaccharide 1,2-N-acetylglucosaminetransferase (EC:2.4.1.56)
    Gene namesi
    Name:waaU
    Synonyms:rfaK, waaK
    Ordered Locus Names:b3623, JW3598
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG11423. waaU.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 357357Lipopolysaccharide 1,2-N-acetylglucosaminetransferasePRO_0000097283Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP27242.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-10672N.
    IntActiP27242. 7 interactions.
    MINTiMINT-1231283.
    STRINGi511145.b3623.

    Structurei

    3D structure databases

    ProteinModelPortaliP27242.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0859.
    HOGENOMiHOG000054846.
    KOiK03277.
    OMAiHIASGFN.
    OrthoDBiEOG6B8XFH.
    PhylomeDBiP27242.

    Family and domain databases

    InterProiIPR002201. Glyco_trans_9.
    [Graphical view]
    PfamiPF01075. Glyco_transf_9. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P27242-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRLGTFHKKK RFYINKIKIN FLSFLFRNKI NNQITDPAQV KSCLIIHDNN    50
    KLGDLIVLSS IYRELYSKGV KITLLTNRKG GEFLSNNKNI FEFCIKESTG 100
    FLEMLTLCKH LRDLQFDIVL DPFETMPSFK HSLILSSLKD SYILGFDHWY 150
    KRYYSFYHPH DECLKEHMST RAIEILKHIY GEGKFSTNYD LHLPVDVEDK 200
    IKEFIGDTRI VIINPLGAKK ICRLTFEQIK VIYQEVKTHF ENYRIIFTGL 250
    PQDLLTIPIL EIETLPFDEF IYTVALTKYS DFVISVDTAL VHIAAAYHKP 300
    TLAFYPNSRT PEYPSHLIWS PNHHKSIQIV SPTYTVKDID TETLTNSVKR 350
    LSCIDKK 357
    Length:357
    Mass (Da):41,729
    Last modified:October 1, 1994 - v2
    Checksum:i951523B8192616F5
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti293 – 2931I → M in AAA24523. (PubMed:1624462)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M95398 Genomic DNA. Translation: AAA24523.1.
    U00039 Genomic DNA. Translation: AAB18600.1.
    U00096 Genomic DNA. Translation: AAC76647.1.
    AP009048 Genomic DNA. Translation: BAE77669.1.
    PIRiA65163.
    RefSeqiNP_418080.1. NC_000913.3.
    YP_491810.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC76647; AAC76647; b3623.
    BAE77669; BAE77669; BAE77669.
    GeneIDi12934311.
    948147.
    KEGGiecj:Y75_p3551.
    eco:b3623.
    PATRICi32122733. VBIEscCol129921_3743.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M95398 Genomic DNA. Translation: AAA24523.1 .
    U00039 Genomic DNA. Translation: AAB18600.1 .
    U00096 Genomic DNA. Translation: AAC76647.1 .
    AP009048 Genomic DNA. Translation: BAE77669.1 .
    PIRi A65163.
    RefSeqi NP_418080.1. NC_000913.3.
    YP_491810.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P27242.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-10672N.
    IntActi P27242. 7 interactions.
    MINTi MINT-1231283.
    STRINGi 511145.b3623.

    Protein family/group databases

    CAZyi GT9. Glycosyltransferase Family 9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC76647 ; AAC76647 ; b3623 .
    BAE77669 ; BAE77669 ; BAE77669 .
    GeneIDi 12934311.
    948147.
    KEGGi ecj:Y75_p3551.
    eco:b3623.
    PATRICi 32122733. VBIEscCol129921_3743.

    Organism-specific databases

    EchoBASEi EB1393.
    EcoGenei EG11423. waaU.

    Phylogenomic databases

    eggNOGi COG0859.
    HOGENOMi HOG000054846.
    KOi K03277.
    OMAi HIASGFN.
    OrthoDBi EOG6B8XFH.
    PhylomeDBi P27242.

    Enzyme and pathway databases

    UniPathwayi UPA00958 .
    BioCyci EcoCyc:EG11423-MONOMER.
    ECOL316407:JW3598-MONOMER.
    MetaCyc:EG11423-MONOMER.

    Miscellaneous databases

    PROi P27242.

    Gene expression databases

    Genevestigatori P27242.

    Family and domain databases

    InterProi IPR002201. Glyco_trans_9.
    [Graphical view ]
    Pfami PF01075. Glyco_transf_9. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparison of lipopolysaccharide biosynthesis genes rfaK, rfaL, rfaY, and rfaZ of Escherichia coli K-12 and Salmonella typhimurium."
      Klena J.D., Pradel E., Schnaitman C.A.
      J. Bacteriol. 174:4746-4752(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: K12.
    2. "Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes."
      Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.
      Nucleic Acids Res. 22:2576-2586(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiWAAU_ECOLI
    AccessioniPrimary (citable) accession number: P27242
    Secondary accession number(s): Q2M7T7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1992
    Last sequence update: October 1, 1994
    Last modified: October 1, 2014
    This is version 108 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways

    External Data

    Dasty 3