P27241 (RFAZ_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Lipopolysaccharide core biosynthesis protein rfaZ

Gene names

Name:	rfaZ
Ordered Locus Names:	b3624, JW3599

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	283 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Pathway

Bacterial outer membrane biogenesis; LPS core biosynthesis.

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 283	283	Lipopolysaccharide core biosynthesis protein rfaZ		PRO_0000097290
Experimental info
	Sequence conflict	58	1	S → G in AAA24522. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P27241 [UniParc]. Last modified October 1, 1994. Version 2. Checksum: 7441DE0DEF192580	FASTA	283	32,920
	10 20 30 40 50 60 MKNIRYIDKK DVENLIENKI SDDVIIFLSG PTSQKTPLSV LRTKDIIAVN GSAQYLLSNN 70 80 90 100 110 120 IVPFIYVLTD VRFLHQRRDD FYKFSQRSRY TIVNVDVYEH ASKEDKLYIL QNCLVLRSFY 130 140 150 160 170 180 RREKGGFIKK IKFNILRQIH KELLISVPLS KKGRLVGFCK DISLGYCSCH TIAFAAIQIA 190 200 210 220 230 240 YSLKYARIIC SGLDLTGSCS RFYDENKNPM PSELSRDLFK ILPFFRFMHD NVKDINIYNL 250 260 270 280 SDDTAISYDV IPFIKLQDIS AEESKDMTRK KMQYRTSTDS YAN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparison of lipopolysaccharide biosynthesis genes rfaK, rfaL, rfaY, and rfaZ of Escherichia coli K-12 and Salmonella typhimurium." Klena J.D., Pradel E., Schnaitman C.A. J. Bacteriol. 174:4746-4752(1992) [PubMed: 1624462] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12.
[2]	"Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes." Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R. Nucleic Acids Res. 22:2576-2586(1994) [PubMed: 8041620] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M95398 Genomic DNA. Translation: AAA24522.1. U00039 Genomic DNA. Translation: AAB18601.1. U00096 Genomic DNA. Translation: AAC76648.1. AP009048 Genomic DNA. Translation: BAE77668.1.
PIR	S47845.
RefSeq	NP_418081.1. NC_000913.2.
3D structure databases
ProteinModelPortal	P27241.
ModBase	Search...
Protein-protein interaction databases
IntAct	P27241. 7 interactions.
Protein family/group databases
CAZy	GT73. Glycosyltransferase Family 73.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000002894; EBESCP00000002894; EBESCG00000002362. EBESCT00000002895; EBESCP00000002895; EBESCG00000002362. EBESCT00000017924; EBESCP00000017215; EBESCG00000016980.
GeneID	948146.
GenomeReviews	Gene locus JW3599 in contig AP009048_GR. Gene locus b3624 in contig U00096_GR.
KEGG	ecj:JW3599. eco:b3624.
PATRIC	32122735. VBIEscCol129921_3744.
Organism-specific databases
EchoBASE	EB1396.
EcoGene	EG11426. rfaZ.
Phylogenomic databases
eggNOG	NOG10705.
GeneTree	EBGT00050000011970.
HOGENOM	HBG467987.
OMA	PCGLDQH.
ProtClustDB	PRK09822.
Enzyme and pathway databases
BioCyc	EcoCyc:EG11426-MONOMER.
Gene expression databases
Genevestigator	P27241.
Family and domain databases
InterPro	IPR009251. A-2_3-sialyltransferase. [Graphical view]
Gene3D	G3DSA:3.90.1480.10. A-2_3-sialyltransferase. 1 hit.
KO	K12981.
ProtoNet	Search...

Entry information

Entry name

RFAZ_ECOLI

Accession

Primary (citable) accession number: P27241
Secondary accession number(s): Q2M7T8

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	October 1, 1994
Last modified:	January 25, 2012
This is version 75 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program