P27178 (ATP6_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATP synthase subunit a

Alternative name(s):
ATP synthase F0 sector subunit a
F-ATPase subunit 6

Gene names

Name:	atpB
Synonyms:	atpI
Ordered Locus Names:	sll1322

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane By similarity. HAMAP MF_01393
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has four main subunits: a, b, b' and c By similarity.
Subcellular location	Cellular thylakoid membrane; Multi-pass membrane protein By similarity HAMAP MF_01393.
Sequence similarities	Belongs to the ATPase A chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(0) Membrane Thylakoid
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW proton-transporting ATP synthase complex, coupling factor F(o) Inferred from electronic annotation. Source: UniProtKB-KW thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydrogen ion transmembrane transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	ATP synthase subunit a HAMAP MF_01393		PRO_0000082076
Regions
	Transmembrane	27 – 47	21	Helical; Potential
	Transmembrane	61 – 81	21	Helical; Potential
	Transmembrane	120 – 140	21	Helical; Potential
	Transmembrane	159 – 179	21	Helical; Potential
	Transmembrane	225 – 245	21	Helical; Potential
	Transmembrane	246 – 266	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P27178 [UniParc]. Last modified August 1, 1992. Version 1. Checksum: E65E9DE31C7621FF	FASTA	276	30,698
	10 20 30 40 50 60 MQGSLSWLLR FVEGQQLSSL PRQSHRITML AGLSVLNLFP LAALEVGQQW YWEIGNLKLH 70 80 90 100 110 120 GQTFATSWFV ILLLVIASLA ATRNVQRVPS GIQNLMEYVL EFLRDLARNQ LGEKEYRPWL 130 140 150 160 170 180 PFIGTLFLFI FVSNWSGALL PWKLIHIPDG AELAAPTNDI NTTVALALLT SLAYFYAGLR 190 200 210 220 230 240 KKGLGYFANY VQPIPVLLPI KILEDFTKPL SLSFRLFGNI LADELVVAVL VLLVPLLVPL 250 260 270 PLMALGLFTS AIQALVFATL AGAYIHEAIE SEGEEH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The atp1 and atp2 operons of the cyanobacterium Synechocystis sp. PCC 6803." Lill H., Nelson N. Plant Mol. Biol. 17:641-652(1991) [PubMed: 1832989] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X58128 Genomic DNA. Translation: CAA41130.1. BA000022 Genomic DNA. Translation: BAA16740.1.
PIR	PWYBAA. S17746.
RefSeq	NP_440060.1. NC_000911.1.
3D structure databases
ProteinModelPortal	P27178.
ModBase	Search...
Protein-protein interaction databases
IntAct	P27178. 2 interactions.
STRING	P27178.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	953359.
GenomeReviews	Gene locus sll1322 in contig BA000022_GR.
KEGG	syn:sll1322.
NMPDR	fig|1148.1.peg.161.
PATRIC	23837202. VBISynSp132158_0176.
Phylogenomic databases
eggNOG	COG0356.
HOGENOM	HBG734175.
OMA	LHGQVFL.
PhylomeDB	P27178.
ProtClustDB	PRK05815.
Enzyme and pathway databases
BioCyc	SSP1148:SLL1322-MONOMER.
Family and domain databases
HAMAP	MF_01393. ATP_synth_a_bact. [Tree]
InterPro	IPR000568. ATPase_F0-cplx_asu. IPR023011. ATPase_F0-cplx_asu_AS. [Graphical view]
Gene3D	G3DSA:1.20.120.220. ATPase_F0_A. 1 hit.
KO	K02108.
PANTHER	PTHR11410. ATPase_F0_A. 1 hit.
Pfam	PF00119. ATP-synt_A. 1 hit. [Graphical view]
PRINTS	PR00123. ATPASEA.
SUPFAM	SSF81336. ATPase_F0_A. 1 hit.
TIGRFAMs	TIGR01131. ATP_synt_6_or_A. 1 hit.
PROSITE	PS00449. ATPASE_A. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATP6_SYNY3

Accession

Primary (citable) accession number: P27178

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	August 1, 1992
Last modified:	January 25, 2012
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program