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P27152

- RS5_THETH

UniProt

P27152 - RS5_THETH

Protein

30S ribosomal protein S5

Gene

rpsE

Organism
Thermus thermophilus
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    With S4 and S12 plays an important role in translational accuracy.By similarity
    Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.By similarity

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: UniProtKB-HAMAP

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    30S ribosomal protein S5
    Gene namesi
    Name:rpsE
    Synonyms:rps5
    OrganismiThermus thermophilus
    Taxonomic identifieri274 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

    Subcellular locationi

    GO - Cellular componenti

    1. small ribosomal subunit Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 16216130S ribosomal protein S5PRO_0000131622Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 30S ribosomal subunit. Contacts proteins S4 and S8 By similarity.By similarity

    Protein-protein interaction databases

    STRINGi262724.TTC1311.

    Structurei

    Secondary structure

    1
    162
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi9 – 2012
    Beta strandi23 – 3513
    Beta strandi37 – 5014
    Helixi51 – 6313
    Beta strandi64 – 685
    Beta strandi72 – 754
    Beta strandi80 – 845
    Beta strandi87 – 937
    Helixi104 – 1107
    Turni111 – 1144
    Beta strandi117 – 1248
    Helixi128 – 13912
    Helixi145 – 1517

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1TWTmodel-H2-162[»]
    4BYBX-ray3.35E1-162[»]
    ProteinModelPortaliP27152.
    SMRiP27152. Positions 1-157.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini6 – 6964S5 DRBMAdd
    BLAST

    Domaini

    The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.

    Sequence similaritiesi

    Belongs to the ribosomal protein S5P family.Curated
    Contains 1 S5 DRBM domain.Curated

    Family and domain databases

    Gene3Di3.30.160.20. 1 hit.
    3.30.230.10. 1 hit.
    HAMAPiMF_01307_B. Ribosomal_S5_B.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR000851. Ribosomal_S5.
    IPR005712. Ribosomal_S5_bac-type.
    IPR005324. Ribosomal_S5_C.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR013810. Ribosomal_S5_N.
    IPR018192. Ribosomal_S5_N_CS.
    [Graphical view]
    PANTHERiPTHR13718. PTHR13718. 1 hit.
    PfamiPF00333. Ribosomal_S5. 1 hit.
    PF03719. Ribosomal_S5_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    TIGRFAMsiTIGR01021. rpsE_bact. 1 hit.
    PROSITEiPS00585. RIBOSOMAL_S5. 1 hit.
    PS50881. S5_DSRBD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P27152-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPETDFEEKM ILIRRTARMQ AGGRRFRFGA LVVVGDRQGR VGLGFGKAPE    50
    VPLAVQKAGY YARRNMVEVP LQNGTIPHEI EVEFGASKIV LKPAAPGTGV 100
    IAGAVPRAIL ELAGVTDILT KELGSRNPIN IAYATMEALR QLRTKADVER 150
    LRKGEAHAQA QG 162
    Length:162
    Mass (Da):17,557
    Last modified:January 23, 2007 - v4
    Checksum:iBE3367CB619E68D2
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti2 – 21P → D AA sequence (PubMed:1637860)Curated
    Sequence conflicti5 – 51D → F AA sequence (PubMed:1637860)Curated
    Sequence conflicti24 – 241R → V AA sequence (PubMed:1637860)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X90765 Genomic DNA. Translation: CAA62290.1.
    PIRiA48401.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X90765 Genomic DNA. Translation: CAA62290.1 .
    PIRi A48401.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1TWT model - H 2-162 [» ]
    4BYB X-ray 3.35 E 1-162 [» ]
    ProteinModelPortali P27152.
    SMRi P27152. Positions 1-157.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262724.TTC1311.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.30.160.20. 1 hit.
    3.30.230.10. 1 hit.
    HAMAPi MF_01307_B. Ribosomal_S5_B.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR000851. Ribosomal_S5.
    IPR005712. Ribosomal_S5_bac-type.
    IPR005324. Ribosomal_S5_C.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR013810. Ribosomal_S5_N.
    IPR018192. Ribosomal_S5_N_CS.
    [Graphical view ]
    PANTHERi PTHR13718. PTHR13718. 1 hit.
    Pfami PF00333. Ribosomal_S5. 1 hit.
    PF03719. Ribosomal_S5_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    TIGRFAMsi TIGR01021. rpsE_bact. 1 hit.
    PROSITEi PS00585. RIBOSOMAL_S5. 1 hit.
    PS50881. S5_DSRBD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequencing and analysis of the Thermus thermophilus ribosomal protein gene cluster equivalent to the spectinomycin operon."
      Vysotskaya V.S., Shcherbakov D.V., Garber M.B.
      Gene 193:23-30(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: VK1.
    2. Cited for: PROTEIN SEQUENCE OF 2-26.
      Strain: VK1.

    Entry informationi

    Entry nameiRS5_THETH
    AccessioniPrimary (citable) accession number: P27152
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1992
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 90 of the entry and version 4 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3