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Protein

Lipopolysaccharide 1,3-galactosyltransferase

Gene

rfaI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-alpha-D-galactose + [lipopolysaccharide] = UDP + 3-alpha-D-galactosyl-[lipopolysaccharide].

Pathwayi: LPS core biosynthesis

This protein is involved in the pathway LPS core biosynthesis, which is part of Bacterial outer membrane biogenesis.
View all proteins of this organism that are known to be involved in the pathway LPS core biosynthesis and in Bacterial outer membrane biogenesis.

GO - Molecular functioni

GO - Biological processi

  • lipopolysaccharide core region biosynthetic process Source: EcoCyc

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processLipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11352-MONOMER
MetaCyc:EG11352-MONOMER
UniPathwayiUPA00958

Protein family/group databases

CAZyiGT8 Glycosyltransferase Family 8

Names & Taxonomyi

Protein namesi
Recommended name:
Lipopolysaccharide 1,3-galactosyltransferase (EC:2.4.1.44)
Alternative name(s):
Lipopolysaccharide 3-alpha-galactosyltransferase
Gene namesi
Name:rfaI
Synonyms:waaI
Ordered Locus Names:b3627, JW3602
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11352 rfaI

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002060641 – 339Lipopolysaccharide 1,3-galactosyltransferaseAdd BLAST339

Proteomic databases

PaxDbiP27128
PRIDEiP27128

Interactioni

Protein-protein interaction databases

BioGridi4263412, 188 interactors
DIPiDIP-10670N
IntActiP27128, 3 interactors
STRINGi316385.ECDH10B_3809

Structurei

3D structure databases

ProteinModelPortaliP27128
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 8 family.Curated

Phylogenomic databases

eggNOGiENOG4106AH0 Bacteria
COG1442 LUCA
HOGENOMiHOG000126190
InParanoidiP27128
KOiK03275
OMAiIWSDVDV
PhylomeDBiP27128

Family and domain databases

Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR002495 Glyco_trans_8
IPR013645 Glyco_transf_8N
IPR029044 Nucleotide-diphossugar_trans
PfamiView protein in Pfam
PF01501 Glyco_transf_8, 1 hit
PF08437 Glyco_transf_8C, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit

Sequencei

Sequence statusi: Complete.

P27128-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQVFFQETE FLNSVIDYDH KVETENLCLD IAYGTDKNFL FGCGISIASI
60 70 80 90 100
LKYNEGSRLC FHIFTDYFGD DDRKYFDALA LQYKTRIKIY LINGDRLRSL
110 120 130 140 150
PSTKNWTHAI YFRFVIADYF INKAPKVLYL DADIICQGTI EPLINFSFPD
160 170 180 190 200
DKVAMVVTEG QADWWEKRAH SLGVAGIAKG YFNSGFLLIN TAQWAAQQVS
210 220 230 240 250
ARAIAMLNEP EIIKKITHPD QDVLNMLLAD KLIFADIKYN TQFSLNYQLK
260 270 280 290 300
ESFINPVTND TIFIHYIGPT KPWHDWAWDY PVSQAFMEAK NASPWKNTAL
310 320 330
LKPNNSNQLR YSAKHMLKKH RYLKGFSNYL FYFIEKIKH
Length:339
Mass (Da):39,423
Last modified:August 1, 1992 - v1
Checksum:i068CA689C1E0C1E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M80599 Genomic DNA Translation: AAA24086.1
U00039 Genomic DNA Translation: AAB18604.1
U00096 Genomic DNA Translation: AAC76651.1
AP009048 Genomic DNA Translation: BAE77665.1
PIRiC42982
RefSeqiNP_418084.1, NC_000913.3
WP_001188013.1, NZ_CP014272.1

Genome annotation databases

EnsemblBacteriaiAAC76651; AAC76651; b3627
BAE77665; BAE77665; BAE77665
GeneIDi948143
KEGGiecj:JW3602
eco:b3627
PATRICifig|1411691.4.peg.3079

Similar proteinsi

Entry informationi

Entry nameiRFAI_ECOLI
AccessioniPrimary (citable) accession number: P27128
Secondary accession number(s): Q2M7U1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: March 28, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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