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Protein

ADP,ATP carrier protein, mitochondrial

Gene

ANT1

Organism
Solanum tuberosum (Potato)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.

Miscellaneous

The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. At least 2 of the odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei158NucleotideBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein, mitochondrial
Alternative name(s):
ADP/ATP translocase
Adenine nucleotide translocator
Short name:
ANT
Gene namesi
Name:ANT1
Synonyms:AAC
OrganismiSolanum tuberosum (Potato)
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
Proteomesi
  • UP000011115 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei82 – 116Helical; Name=1By similarityAdd BLAST35
Transmembranei153 – 177Helical; Name=2By similarityAdd BLAST25
Transmembranei186 – 220Helical; Name=3By similarityAdd BLAST35
Transmembranei256 – 283Helical; Name=4By similarityAdd BLAST28
Transmembranei288 – 322Helical; Name=5By similarityAdd BLAST35
Transmembranei351 – 376Helical; Name=6By similarityAdd BLAST26

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei‹1 – 76MitochondrionSequence analysisAdd BLAST›76
ChainiPRO_000001925277 – 386ADP,ATP carrier protein, mitochondrialAdd BLAST310

Proteomic databases

PRIDEiP27081.

Interactioni

Subunit structurei

Homodimer.

Protein-protein interaction databases

STRINGi4113.PGSC0003DMT400081472.

Structurei

3D structure databases

ProteinModelPortaliP27081.
SMRiP27081.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati83 – 176Solcar 1Add BLAST94
Repeati188 – 281Solcar 2Add BLAST94
Repeati289 – 375Solcar 3Add BLAST87

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi316 – 321Substrate recognitionBy similarity6

Sequence similaritiesi

Keywords - Domaini

Repeat, Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
InParanoidiP27081.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P27081-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ADNQHPTVYQ KVASQMHLSS SLSQDVHARY GGIQRPALSQ RRFPYGNYSN
60 70 80 90 100
AGLQTCQATQ DLSLIAANAS PVFVQAPQEK GLAAFATDFL MGGVSAAVSK
110 120 130 140 150
TAAAPIERVK LLIQNQDEMI KAGRLSEPYK GIGDCFSRTI KDEGFAALWR
160 170 180 190 200
GNTANVIRYF PTQALNFAFK DYFKRLFNFK KDRDGYWKWF AGNLASGGGA
210 220 230 240 250
GASSLLFVYS LDYARTRLAN DAKAAKKGGG GRQFDGLVDV YRKTLKSDGV
260 270 280 290 300
AGLYRGFNIS CVGIIVYRGL YFGMYDSLKP VLLTGKMEDS FFASFALGWL
310 320 330 340 350
ITNGAGLASY PIDTVRRRMM MTSGEAVKYK SSFDAFNQIL KNEGPKSLFK
360 370 380
GAGANVLRAV AGAGVLAGYD KLQVIVFGKK YGSGGG
Length:386
Mass (Da):41,829
Last modified:August 1, 1992 - v1
Checksum:iFF08A500ECDFBB93
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57557 mRNA. Translation: CAA40782.1.
PIRiS14874.
UniGeneiStu.2012.

Similar proteinsi

Entry informationi

Entry nameiADT2_SOLTU
AccessioniPrimary (citable) accession number: P27081
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: March 15, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families