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Protein

ADP,ATP carrier protein

Gene

ABT

Organism
Chlamydomonas reinhardtii (Chlamydomonas smithii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.

Miscellaneous

The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. At least 2 of the odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei81NucleotideBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein
Alternative name(s):
ADP/ATP translocase
Adenine nucleotide translocator
Short name:
ANT
Gene namesi
Name:ABT
OrganismiChlamydomonas reinhardtii (Chlamydomonas smithii)
Taxonomic identifieri3055 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaChlorophyceaeChlamydomonadalesChlamydomonadaceaeChlamydomonas

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 39Helical; Name=1By similarityAdd BLAST33
Transmembranei76 – 100Helical; Name=2By similarityAdd BLAST25
Transmembranei108 – 142Helical; Name=3By similarityAdd BLAST35
Transmembranei178 – 205Helical; Name=4By similarityAdd BLAST28
Transmembranei210 – 244Helical; Name=5By similarityAdd BLAST35
Transmembranei273 – 298Helical; Name=6By similarityAdd BLAST26

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000905881 – 308ADP,ATP carrier proteinAdd BLAST308

Proteomic databases

PaxDbiP27080.
PRIDEiP27080.
ProMEXiP27080.

Interactioni

Subunit structurei

Homodimer.

Structurei

3D structure databases

ProteinModelPortaliP27080.
SMRiP27080.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati6 – 99Solcar 1Add BLAST94
Repeati110 – 203Solcar 2Add BLAST94
Repeati211 – 297Solcar 3Add BLAST87

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi238 – 243Substrate recognitionBy similarity6

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
KOiK05863.
OMAiNCIAKIF.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom_sf.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

P27080-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEEKNFMV DFLAGGLSAA VSKTAAAPIE RVKLLIQNQD EMIKQGRLAS
60 70 80 90 100
PYKGIGECFV RTVREEGFGS LWRGNTANVI RYFPTQALNF AFKDKFKRMF
110 120 130 140 150
GFNKDKEYWK WFAGNMASGG AAGAVSLSFV YSLDYARTRL ANDAKSAKKG
160 170 180 190 200
GGDRQFNGLV DVYRKTIASD GIAGLYRGFN ISCVGIVVYR GLYFGMYDSL
210 220 230 240 250
KPVVLVGPLA NNFLAAFLLG WGITIGAGLA SYPIDTIRRR MMMTSGSAVK
260 270 280 290 300
YNSSFHCFQE IVKNEGMKSL FKGAGANILR AVAGAGVLAG YDQLQVILLG

KKYGSGEA
Length:308
Mass (Da):33,528
Last modified:August 1, 1992 - v1
Checksum:iD477CF0E72B7A53F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X65194 mRNA. Translation: CAA46311.1.
PIRiS30259.
RefSeqiXP_001695177.1. XM_001695125.1.
UniGeneiCre.8628.

Genome annotation databases

EnsemblPlantsiEDP01885; EDP01885; CHLREDRAFT_196520.
GeneIDi5720839.
GrameneiEDP01885; EDP01885; CHLREDRAFT_196520.
KEGGicre:CHLREDRAFT_196520.

Similar proteinsi

Entry informationi

Entry nameiADT_CHLRE
AccessioniPrimary (citable) accession number: P27080
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: November 22, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families