Reviewed, UniProtKB/Swiss-Prot P27030 (RHAB_SALTY)

Names and origin

Protein names

Recommended name:
    Rhamnulokinase
    EC=2.7.1.5
Alternative name(s):
    Rhamnulose kinase

Gene names

Name:	rhaB
Ordered Locus Names:	STM4047

Organism

Salmonella typhimurium [Complete proteome] [HAMAP]

Taxonomic identifier

90371 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	489 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate. HAMAP MF_01535
Pathway	Carbohydrate degradation; L-rhamnose degradation; glycerone phosphate from L-rhamnose: step 2/3. HAMAP MF_01535
Sequence similarities	Belongs to the rhamnulokinase family.

Ontologies

Keywords
Biological process	Rhamnose metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rhamnose catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW rhamnulokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 489	489	Rhamnulokinase HAMAP MF_01535		PRO_0000090545
Regions
	Region	236 – 238	3	Substrate binding By similarity
Sites
	Binding site	14	1	ATP By similarity
	Binding site	259	1	ATP By similarity
	Binding site	296	1	Substrate By similarity
	Binding site	304	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	P27030-1 [UniParc]. Last modified August 1, 1992. Version 1. Checksum: 47B6CB29F3397F41	FASTA	489	54,578
	10 20 30 40 50 60 MTFRHCVAVD LGASSGRVML ARYDSKHRTL TLREIHRFVN CLQKTDGFDT WDIDSLEKDI 70 80 90 100 110 120 RLGLKKVCNE GILIDSIGID TWGVDYVLLD KQGQRVGLPV SYRDNRTTGI MPQALVQIGK 130 140 150 160 170 180 SEIYRRSGIQ FLPFNTIYQL RALTKQQPEL TAQVAHALLM PDYFSYRLTG EMNWEYTNAT 190 200 210 220 230 240 TTQLVNINTD DWDDTLLAWT GAKKSWFGRP SHPGNVIGDW ICPQGNRIPV VAVASHDTAS 250 260 270 280 290 300 AVIASPLANK HSAYLSSGTW SLMGFESKMP YTTDEALAAN ITNEGGAEGR YRVLKNIMGL 310 320 330 340 350 360 WLLQRVLKER RITDLPALIA QTEALPACRF LINPNDDRFI NPDDMRAEIQ AACRETDQPV 370 380 390 400 410 420 PVSDAELARC IFDSLALLYA DILHEQANLR GEKFTQLHIV GGGCQNSLLN QLCADACGIR 430 440 450 460 470 480 VMAGPVEAST LGNIGIQLMT LDELNNVDDF RQVVSANYDL TTYIPNPDSE IARHVAQFQP KRQTKELCA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and characterization of the L-rhamnose regulon in Salmonella typhimurium LT2." Nishitani J., Wilcox G. Gene 105:37-42(1991) [PubMed: 1657713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: LT2.
[2]	"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2." McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K. Nature 413:852-856(2001) [PubMed: 11677609] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LT2 / SGSC1412 / ATCC 700720.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X57299 Genomic DNA. Translation: CAA40557.1. AE008889 Genomic DNA. Translation: AAL22887.1.
PIR	JQ1289.
RefSeq	NP_462928.1.
3D structure databases
SMR	P27030. Positions 2-476.
ModBase	Search...
Genome annotation databases
GeneID	1255574.
GenomeReviews	Gene locus STM4047 in contig AE006468_GR.
KEGG	stm:STM4047.
NMPDR	fig|99287.1.peg.3901.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P27030.
OMA	P27030. EIHRFKN.
Enzyme and pathway databases
BioCyc	STYP99287:STM4047-MON.
BRENDA	2.7.1.5. 2.
Family and domain databases
HAMAP	MF_01535. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018484. Carb_kinase_FGGY_N. IPR013449. Rhamnulokinase. [Graphical view]
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR02627. rhamnulo_kin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RHAB_SALTY

Accession

Primary (citable) accession number: P27030

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	August 1, 1992
Last modified:	June 16, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)