Reviewed, UniProtKB/Swiss-Prot P26984 (SCRK_SALTY)

Names and origin

Protein names

Recommended name:
    Fructokinase
    EC=2.7.1.4

Gene names

Name:

scrK

Encoded on

Plasmid pUR400

Organism

Salmonella typhimurium

Taxonomic identifier

90371 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + D-fructose = ADP + D-fructose 6-phosphate.
Sequence similarities	Belongs to the carbohydrate kinase pfkB family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Plasmid
Gene Ontology (GO)
Biological process	D-ribose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW fructokinase activity Inferred from electronic annotation. Source: EC ribokinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 307	307	Fructokinase		PRO_0000080138

Sequences

	Sequence		Length	Mass (Da)
	P26984-1 [UniParc]. Last modified August 1, 1992. Version 1. Checksum: E01CB770CE20B329	FASTA	307	32,916
	10 20 30 40 50 60 MNAKVWVLGD AVVDLLPESE GRLLQCPGGA PANVAVGVAR LGGNSGFIGA VGGDPFGRYM 70 80 90 100 110 120 RHTLQQEQVD VSHMYLDDQH RTSTVVVDLD DQGERTFTFM VRPSADLFLV EEDLPQFAAG 130 140 150 160 170 180 QWLHVCSIAL SAEPSRSTTF AAMESIRSAG GRVSFDPNIR PDLWQDQALL LACLDRALHM 190 200 210 220 230 240 ANVVKLSEEE LVFISSSNDL AYGIASVTER YQPELLLVTR GKAGVLAAFQ QKFTHFNARP 250 260 270 280 290 300 VASVDTTGAG DAFVAGLLAS LAANGMPTDM TALEPTLTLA QTCGALATTA KGAMTALPYQ RDLNRQF

References

[1]	"Molecular analysis of two fructokinases involved in sucrose metabolism of enteric bacteria." Aulkemeyer P., Ebner R., Heilenmann G., Jahreis K., Schmid K., Wrieden S., Lengeler J.W. Mol. Microbiol. 5:2913-2922(1991) [PubMed: 1809835] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	X61005 Genomic DNA. Translation: CAA43323.1.
PIR	S18524.
3D structure databases
HSSP	HSSP built from PDB template 1LII based on UniProtKB Q9TVW2.
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.7.1.4. 2.
Family and domain databases
InterPro	IPR011611. Carb/pur_kinase. IPR002173. Carboh/pur_kinase_PfkB_CS. IPR002139. Ribokinase. [Graphical view]
Pfam	PF00294. PfkB. 1 hit. [Graphical view]
PRINTS	PR00990. RIBOKINASE.
PROSITE	PS00583. PFKB_KINASES_1. 1 hit. PS00584. PFKB_KINASES_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SCRK_SALTY

Accession

Primary (citable) accession number: P26984

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	August 1, 1992
Last modified:	June 16, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)