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Protein

Non-specific acid phosphatase

Gene

phoN

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

SABIO-RKP26976.

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific acid phosphatase (EC:3.1.3.2)
Short name:
NSAP
Gene namesi
Name:phoN
Ordered Locus Names:STM4319
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000002400221 – 250Non-specific acid phosphataseAdd BLAST230

Proteomic databases

PaxDbiP26976.
PRIDEiP26976.

Interactioni

Subunit structurei

Homodimer.Curated

Protein-protein interaction databases

STRINGi99287.STM4319.

Structurei

3D structure databases

ProteinModelPortaliP26976.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105SBG. Bacteria.
COG0671. LUCA.
HOGENOMiHOG000233901.
KOiK09474.
OMAiMGQSRVI.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR011158. Acid_Pase_ClassA.
IPR001011. Acid_Pase_classA_bac.
IPR018296. Acid_Pase_classA_bac_CS.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
PIRSFiPIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTSiPR00483. BACPHPHTASE.
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.
PROSITEiPS01157. ACID_PHOSPH_CL_A. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P26976-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSRYLVFFL PLIVAKYTSA ETVQPFHSPE ESVNSQFYLP PPPGNDDPAY
60 70 80 90 100
RYDKEAYFKG YAIKGSPRWK QAAEDADVSV ENIARIFSPV VGAKINPKDT
110 120 130 140 150
PETWNMLKNL LTMGGYYATA SAKKYYMRTR PFVLFNHSTC RPEDENTLRK
160 170 180 190 200
NGSYPSGHTA YGTLLALVLS EARPERAQEL ARRGWEFGQS RVICGAHWQS
210 220 230 240 250
DVDAGRYVGA VEFARLQTIP AFQKSLAKVR EELNDKNNLL SKEDHPKLNY
Length:250
Mass (Da):28,382
Last modified:August 1, 1992 - v1
Checksum:iCFE8DA409BD57573
GO

Sequence cautioni

The sequence CAA41760 differs from that shown. Reason: Frameshift at position 229.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63599 Genomic DNA. Translation: CAA45144.1.
X59036 Genomic DNA. Translation: CAA41760.1. Frameshift.
AE006468 Genomic DNA. Translation: AAL23143.1.
PIRiS20958. A41330.
RefSeqiNP_463184.1. NC_003197.1.
WP_000842434.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL23143; AAL23143; STM4319.
GeneIDi1255845.
KEGGistm:STM4319.
PATRICi32387549. VBISalEnt20916_4542.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63599 Genomic DNA. Translation: CAA45144.1.
X59036 Genomic DNA. Translation: CAA41760.1. Frameshift.
AE006468 Genomic DNA. Translation: AAL23143.1.
PIRiS20958. A41330.
RefSeqiNP_463184.1. NC_003197.1.
WP_000842434.1. NC_003197.1.

3D structure databases

ProteinModelPortaliP26976.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM4319.

Proteomic databases

PaxDbiP26976.
PRIDEiP26976.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL23143; AAL23143; STM4319.
GeneIDi1255845.
KEGGistm:STM4319.
PATRICi32387549. VBISalEnt20916_4542.

Phylogenomic databases

eggNOGiENOG4105SBG. Bacteria.
COG0671. LUCA.
HOGENOMiHOG000233901.
KOiK09474.
OMAiMGQSRVI.

Enzyme and pathway databases

SABIO-RKP26976.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR011158. Acid_Pase_ClassA.
IPR001011. Acid_Pase_classA_bac.
IPR018296. Acid_Pase_classA_bac_CS.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
PIRSFiPIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTSiPR00483. BACPHPHTASE.
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.
PROSITEiPS01157. ACID_PHOSPH_CL_A. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPHON_SALTY
AccessioniPrimary (citable) accession number: P26976
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: November 2, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.