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P26976

- PHON_SALTY

UniProt

P26976 - PHON_SALTY

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Protein

Non-specific acid phosphatase

Gene

phoN

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSENT99287:GCTI-4350-MONOMER.
SABIO-RKP26976.

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific acid phosphatase (EC:3.1.3.2)
Short name:
NSAP
Gene namesi
Name:phoN
Ordered Locus Names:STM4319
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001014: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
  2. outer membrane-bounded periplasmic space Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence AnalysisAdd
BLAST
Chaini21 – 250230Non-specific acid phosphatasePRO_0000024002Add
BLAST

Proteomic databases

PaxDbiP26976.
PRIDEiP26976.

Interactioni

Subunit structurei

Homodimer.Curated

Protein-protein interaction databases

STRINGi99287.STM4319.

Structurei

3D structure databases

ProteinModelPortaliP26976.
SMRiP26976. Positions 23-241.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG0671.
HOGENOMiHOG000233901.
KOiK09474.
OMAiARYQRPR.
OrthoDBiEOG6H1Q3K.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR011158. Acid_Pase_ClassA.
IPR001011. Acid_Pase_classA_bac.
IPR018296. Acid_Pase_classA_bac_CS.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
PIRSFiPIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTSiPR00483. BACPHPHTASE.
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.
PROSITEiPS01157. ACID_PHOSPH_CL_A. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P26976-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKSRYLVFFL PLIVAKYTSA ETVQPFHSPE ESVNSQFYLP PPPGNDDPAY
60 70 80 90 100
RYDKEAYFKG YAIKGSPRWK QAAEDADVSV ENIARIFSPV VGAKINPKDT
110 120 130 140 150
PETWNMLKNL LTMGGYYATA SAKKYYMRTR PFVLFNHSTC RPEDENTLRK
160 170 180 190 200
NGSYPSGHTA YGTLLALVLS EARPERAQEL ARRGWEFGQS RVICGAHWQS
210 220 230 240 250
DVDAGRYVGA VEFARLQTIP AFQKSLAKVR EELNDKNNLL SKEDHPKLNY
Length:250
Mass (Da):28,382
Last modified:August 1, 1992 - v1
Checksum:iCFE8DA409BD57573
GO

Sequence cautioni

The sequence CAA41760.1 differs from that shown. Reason: Frameshift at position 229.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X63599 Genomic DNA. Translation: CAA45144.1.
X59036 Genomic DNA. Translation: CAA41760.1. Frameshift.
AE006468 Genomic DNA. Translation: AAL23143.1.
PIRiS20958. A41330.
RefSeqiNP_463184.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL23143; AAL23143; STM4319.
GeneIDi1255845.
KEGGistm:STM4319.
PATRICi32387549. VBISalEnt20916_4542.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X63599 Genomic DNA. Translation: CAA45144.1 .
X59036 Genomic DNA. Translation: CAA41760.1 . Frameshift.
AE006468 Genomic DNA. Translation: AAL23143.1 .
PIRi S20958. A41330.
RefSeqi NP_463184.1. NC_003197.1.

3D structure databases

ProteinModelPortali P26976.
SMRi P26976. Positions 23-241.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 99287.STM4319.

Proteomic databases

PaxDbi P26976.
PRIDEi P26976.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL23143 ; AAL23143 ; STM4319 .
GeneIDi 1255845.
KEGGi stm:STM4319.
PATRICi 32387549. VBISalEnt20916_4542.

Phylogenomic databases

eggNOGi COG0671.
HOGENOMi HOG000233901.
KOi K09474.
OMAi ARYQRPR.
OrthoDBi EOG6H1Q3K.

Enzyme and pathway databases

BioCyci SENT99287:GCTI-4350-MONOMER.
SABIO-RK P26976.

Family and domain databases

Gene3Di 1.20.144.10. 1 hit.
InterProi IPR011158. Acid_Pase_ClassA.
IPR001011. Acid_Pase_classA_bac.
IPR018296. Acid_Pase_classA_bac_CS.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view ]
Pfami PF01569. PAP2. 1 hit.
[Graphical view ]
PIRSFi PIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTSi PR00483. BACPHPHTASE.
SMARTi SM00014. acidPPc. 1 hit.
[Graphical view ]
SUPFAMi SSF48317. SSF48317. 1 hit.
PROSITEi PS01157. ACID_PHOSPH_CL_A. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Horizontal transfer of a phosphatase gene as evidence for mosaic structure of the Salmonella genome."
    Groisman E.A., Saier M.H. Jr., Ochman H.
    EMBO J. 11:1309-1316(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 14028 / SGSG 2980 / CDC 6516-60 / NCTC 12023.
  2. "Molecular analysis of the Salmonella typhimurium phoN gene, which encodes nonspecific acid phosphatase."
    Kasahara M., Nakata A., Shinagawa H.
    J. Bacteriol. 173:6760-6765(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: LT2.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry nameiPHON_SALTY
AccessioniPrimary (citable) accession number: P26976
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: October 1, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3