Reviewed, UniProtKB/Swiss-Prot P26975 (PHON_PROST)

Names and origin

Protein names

Recommended name:
    Non-specific acid phosphatase
      Short name=NSAP
    EC=3.1.3.2

Gene names

Name:

phoN

Organism

Providencia stuartii

Taxonomic identifier

588 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Providencia

Protein attributes

Sequence length	248 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	A phosphate monoester + H2O = an alcohol + phosphate.
Subcellular location	Periplasm.
Sequence similarities	Belongs to the class A bacterial acid phosphatase family.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Molecular function	Hydrolase
Gene Ontology (GO)
Cellular component	membrane Inferred from electronic annotation. Source: InterPro outer membrane-bounded periplasmic space Inferred from electronic annotation. Source: InterPro
Molecular function	acid phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Potential
	Chain	21 – 248	228	Non-specific acid phosphatase		PRO_0000024000

Sequences

	Sequence		Length	Mass (Da)
	P26975-1 [UniParc]. Last modified August 1, 1992. Version 1. Checksum: 2122A4B95E767CB2	FASTA	248	27,044
	10 20 30 40 50 60 MKKLLAVFCA GAFVSTSVFA AIPPGNDVTT KPDLYYLKNS QAIDSLALLP PPPEVGSILF 70 80 90 100 110 120 LNDQAMYEKG RLLRNTERGE QAAKDADLAA GGVANAFSEA FGYPITEKDA PEIHKLLTNM 130 140 150 160 170 180 IEDAGDLATR SAKEKYMRIR PFAFYGVATC NTKDQDKLSK NGSYPSGHTA IGWASALVLS 190 200 210 220 230 240 EINPENQDKI LKRGYELGQS RVICGYHWQS DVDAARIVAS GAVATLHSNP EFQKQLQKAK DEFAKLKK

References

[1]	Riccio M.L., Lombardi G., Chiesurin A., Satta G. Submitted (FEB-1992) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: PV81.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X64820 Genomic DNA. Translation: CAA46032.1.
PIR	PAOFCS. S19888.
3D structure databases
HSSP	HSSP built from PDB template 1D2T based on UniProtKB Q9S1A6.
SMR	P26975. Positions 25-245.
ModBase	Search...
Enzyme and pathway databases
BRENDA	3.1.3.2. 96137.
Family and domain databases
InterPro	IPR011158. Acid_Pase_ClassA. IPR001011. Acid_Pase_classA_bac. IPR018296. Acid_Pase_classA_bac_CS. IPR016118. P_Acid_Pase/Cl_peroxidase_N. IPR000326. P_Acid_Pase_2/haloperoxidase. [Graphical view]
Gene3D	G3DSA:1.20.144.10. P_Acid_Pase/Cl_peroxidase_N. 1 hit.
Pfam	PF01569. PAP2. 1 hit. [Graphical view]
PIRSF	PIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTS	PR00483. BACPHPHTASE.
ProDom	PD009838. Bac_AcPataseA. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00014. acidPPc. 1 hit. [Graphical view]
PROSITE	PS01157. ACID_PHOSPH_CL_A. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHON_PROST

Accession

Primary (citable) accession number: P26975

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	August 1, 1992
Last modified:	June 16, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)