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Protein

Adult-specific cuticular protein ACP-22

Gene

ACP22

Organism
Tenebrio molitor (Yellow mealworm beetle)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Cuticular proteins play a significant role in determining the physical properties of cuticles.

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Adult-specific cuticular protein ACP-22
Gene namesi
Name:ACP22
OrganismiTenebrio molitor (Yellow mealworm beetle)
Taxonomic identifieri7067 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaColeopteraPolyphagaCucujiformiaTenebrionidaeTenebrio

Subcellular locationi

Keywords - Cellular componenti

Cuticle

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000000641520 – 199Adult-specific cuticular protein ACP-22Add BLAST180

Expressioni

Tissue specificityi

Epidermal regions synthesizing hard cuticle.

Developmental stagei

Preecdysial adult cuticle deposition.

Inductioni

By 20-hydroxyecdysone.

Structurei

3D structure databases

SMRiP26968.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini133 – 199Chitin-binding type R&RPROSITE-ProRule annotationAdd BLAST67

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi21 – 26Poly-Gly6
Compositional biasi34 – 37Poly-Gly4
Compositional biasi63 – 72Poly-Gly10
Compositional biasi88 – 104Poly-GlyAdd BLAST17

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR000618. Insect_cuticle.
PfamiView protein in Pfam
PF00379. Chitin_bind_4. 1 hit.
PROSITEiView protein in PROSITE
PS51155. CHIT_BIND_RR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P26968-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLFIILSVA SFGAIGVLSQ GGGGGGAAGG LLEGGGGFEE YGHRSRGSII
60 70 80 90 100
GLSRGIEIGR HYGGGGGGGG EGEEGREHEL RGGGLELGGG GGGGGGGGGG
110 120 130 140 150
GGEGRHYEIG FGGSHFNTPV DVHHEEAIHL KAHPEYHSDY HVADHKTKDF
160 170 180 190
KSKHEVRDGY KVKGTYSLLE PDHKTVRVVD YVSDKKRGFI ARVSYRKHH
Length:199
Mass (Da):20,710
Last modified:August 1, 1992 - v1
Checksum:i1EBF2D1DBEC6739F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti138S → Y in CAA51290 (PubMed:9087546).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60455 mRNA. Translation: CAA42985.1.
X72783 Genomic DNA. Translation: CAA51290.1.
PIRiS16063.
S32224.

Similar proteinsi

Entry informationi

Entry nameiCU22_TENMO
AccessioniPrimary (citable) accession number: P26968
Secondary accession number(s): Q27015
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: April 12, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)