SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P26941

- TRPF_METTM

UniProt

P26941 - TRPF_METTM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene
trpF, MTBMA_c02370
Organism
Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciMMAR79929:GH5J-238-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:MTBMA_c02370
OrganismiMethanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum)
Taxonomic identifieri79929 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
ProteomesiUP000000345: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotationPRO_0000154408Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP26941.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

HOGENOMiHOG000161598.
KOiK01817.
OMAiCLDFNSG.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

P26941-1 [UniParc]FASTAAdd to Basket

« Hide

MKIKICGLTR EEDVVLADSL GADLLGFIHA RRSPRHLELG DVAELSSLIP    50
DEKAVLVTET SETSRIMEAI DKTGIERIQL HSVSPETAGK IHESLHAEGY 100
SLELTLAVPP LSSHICGHEF QGISGLILDS ASGGRTGGTG KIIPPSDALE 150
LLALIRGMDP SLRVTLAGGL TLEFVRKNRE YVSKFDCLDF NSGIETGPGV 200
KDHEMMAELM NYIEGLPTRK GAIEEI 226
Length:226
Mass (Da):24,383
Last modified:August 1, 1992 - v1
Checksum:iCDE5A34BF155E034
GO

Sequence cautioni

The sequence ADL57846.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M65060 Genomic DNA. Translation: AAA73031.1.
CP001710 Genomic DNA. Translation: ADL57846.1. Different initiation.
RefSeqiYP_003849159.1. NC_014408.1.

Genome annotation databases

EnsemblBacteriaiADL57846; ADL57846; MTBMA_c02370.
GeneIDi9703943.
KEGGimmg:MTBMA_c02370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M65060 Genomic DNA. Translation: AAA73031.1 .
CP001710 Genomic DNA. Translation: ADL57846.1 . Different initiation.
RefSeqi YP_003849159.1. NC_014408.1.

3D structure databases

ProteinModelPortali P26941.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADL57846 ; ADL57846 ; MTBMA_c02370 .
GeneIDi 9703943.
KEGGi mmg:MTBMA_c02370.

Phylogenomic databases

HOGENOMi HOG000161598.
KOi K01817.
OMAi CLDFNSG.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci MMAR79929:GH5J-238-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Tryptophan gene cluster of Methanobacterium thermoautotrophicum Marburg: molecular cloning and nucleotide sequence of a putative trpEGCFBAD operon."
    Meile L., Stettler R., Banholzer R., Kotik M., Leisinger T.
    J. Bacteriol. 173:5017-5023(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg.
  2. "Complete genome sequence of Methanothermobacter marburgensis, a methanoarchaeon model organism."
    Liesegang H., Kaster A.K., Wiezer A., Goenrich M., Wollherr A., Seedorf H., Gottschalk G., Thauer R.K.
    J. Bacteriol. 192:5850-5851(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg.

Entry informationi

Entry nameiTRPF_METTM
AccessioniPrimary (citable) accession number: P26941
Secondary accession number(s): D9PUE8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi