Reviewed, UniProtKB/Swiss-Prot P26938 (TRPC_AZOBR)

Names and origin

Protein names

Recommended name:
    Indole-3-glycerol phosphate synthase
      Short name=IGPS
    EC=4.1.1.48

Gene names

Name:

trpC

Organism

Azospirillum brasilense

Taxonomic identifier

192 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Azospirillum

Protein attributes

Sequence length	262 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Participates in the tryptophan-dependent indole-3-acetic acid production, which is a phytohormone released by A.brasilense. HAMAP MF_00134
Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134
Sequence similarities	Belongs to the trpC family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Decarboxylase Lyase
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 262	262	Indole-3-glycerol phosphate synthase HAMAP MF_00134		PRO_0000154207

Sequences

	Sequence		Length	Mass (Da)
	P26938-1 [UniParc]. Last modified August 1, 1992. Version 1. Checksum: A4CA5CDEAD299927	FASTA	262	28,123
	10 20 30 40 50 60 MSDVLTRICD DKRALVQARK SARPLSAVED DARSADPAGG FIRALRRTVD GGRYGLIAEI 70 80 90 100 110 120 KKASPSKGLI RPDFDPPSLA RAYRGGGATC LSVLTDEPYF QGCDDYLLSA RAAVDLPVLR 130 140 150 160 170 180 KDFMVDPYQI AESRALGADC ILIIMAALSD AQAVEIEDAA IAWGLDVLVE VHNREELDRA 190 200 210 220 230 240 LALKTPLLGV NNRNLKTLAV DIATTEELAA HVPADRMLVA ESGLYSPADL SRMAAVGARC 250 260 FLVGESLMRQ EDVSAATRAL LA

References

[1]

"Relationship between tryptophan biosynthesis and indole-3-acetic acid production in Azospirillum: identification and sequencing of a trpGDC cluster." Zimmer W., Aparicio C., Elmerich C. Mol. Gen. Genet. 229:41-51(1991) [PubMed: 1896020] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 29145 / Sp7 / DSM 1690 / IMET 11303.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X57853 Genomic DNA. Translation: CAA40986.1.
PIR	S17705.
3D structure databases
HSSP	HSSP built from PDB template 1PII based on UniProtKB P00909.
ModBase	Search...
Enzyme and pathway databases
BRENDA	4.1.1.48. 1315.
Family and domain databases
HAMAP	MF_00134. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GPS_central. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
ProDom	PD001511. IGPS. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPC_AZOBR

Accession

Primary (citable) accession number: P26938

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	August 1, 1992
Last modified:	March 3, 2009
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)