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Reviewed, UniProtKB/Swiss-Prot P26922 (TRPG_AZOBR)

Last modified June 16, 2009. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Anthranilate synthase component 2
    EC=4.1.3.27
Alternative name(s):
    Anthranilate synthase component II
    Glutamine amido-transferase
Gene names
Name: trpG
OrganismAzospirillum brasilense
Taxonomic identifier192 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeAzospirillum

Protein attributes

Sequence length196 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existencePredicted.

General annotation (Comments)

Function

Participates in the tryptophan-dependent indole-3-acetic acid production, which is a phytohormone released by A.brasilense.

Catalytic activity

Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.

Subunit structure

Contains 2 chains with different activities: component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity.

Sequence similarities

Contains 1 glutamine amidotransferase type-1 domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 196196Anthranilate synthase component 2
PRO_0000056871

Regions

Domain1 – 195195Glutamine amidotransferase type-1

Sites

Active site801 By similarity
Active site1691 By similarity
Active site1711 By similarity

Sequences

Sequence LengthMass (Da)Tools
P26922-1 [UniParc].

Last modified August 1, 1992. Version 1.
Checksum: BBE41EEB84CC0EAA

FASTA19621,405
        10         20         30         40         50         60 
MLLLIDNYDS FTYNLVHYLG ELGAELDVRR NDSLTVEEAM ALRPEGIVLS PGPCDPDKAG 

        70         80         90        100        110        120 
ICLPLIDAAA KAAVPLMGVC LGHQAIGQPF GGTVVRAPVP MHGKVDRMFH QGRGVLKDLP 

       130        140        150        160        170        180 
SPFRATRYHS LIVERATLPA CLEVTGETED GLIMALSHRE LPIHGVQFHP ESIESEHGHK 

       190 
ILENFLNTTR RLETAA 

« Hide

References

[1]"Relationship between tryptophan biosynthesis and indole-3-acetic acid production in Azospirillum: identification and sequencing of a trpGDC cluster."
Zimmer W., Aparicio C., Elmerich C.
Mol. Gen. Genet. 229:41-51(1991) [PubMed: 1896020] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 29145 / Sp7 / DSM 1690 / IMET 11303.

Cross-references

Sequence databases

X57853 Genomic DNA. Translation: CAA40984.1.
PIRS17703.

3D structure databases

HSSPHSSP built from PDB template 1QDL based on UniProtKB Q06129.
ModBaseSearch...

Enzyme and pathway databases

BRENDA4.1.3.27. 1315.

Family and domain databases

InterProIPR006220. Anth_synthII.
IPR001317. CarbamoylP_synth_GATase.
IPR011702. GATASE.
IPR017926. GATASE_1.
IPR000991. GATase_class1_C.
IPR006221. TrpG_papA.
[Graphical view]
PfamPF00117. GATase. 1 hit.
[Graphical view]
PRINTSPR00097. ANTSNTHASEII.
PR00099. CPSGATASE.
PR00096. GATASE.
TIGRFAMsTIGR00566. trpG_papA. 1 hit.
PROSITEPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRPG_AZOBR
AccessionPrimary (citable) accession number: P26922
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: June 16, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents