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P26875 (RNT1_TRIHA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Guanyl-specific ribonuclease Th1

Short name=RNase Th1
EC=3.1.27.3
OrganismTrichoderma harzianum (Hypocrea lixii)
Taxonomic identifier5544 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesHypocreaceaeTrichoderma

Protein attributes

Sequence length106 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate intermediates.

Sequence similarities

Belongs to the ribonuclease N1/T1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 106106Guanyl-specific ribonuclease Th1
PRO_0000137375

Sites

Active site391 By similarity
Active site581Proton acceptor By similarity
Active site921Proton donor By similarity

Amino acid modifications

Disulfide bond5 ↔ 103 By similarity
Disulfide bond23 ↔ 84 Probable

Sequences

Sequence LengthMass (Da)Tools
P26875 [UniParc].

Last modified August 1, 1992. Version 1.
Checksum: 892A8BFE043AA022

FASTA10610,750
        10         20         30         40         50         60 
DTATCGKVFY SASAVSAASN AACNYVRAGS TAGGSTYPHV YNNYEGFRFK GLSKPFYEFP 

        70         80         90        100 
ILSSGKTYTG GSPGADRVVI NGQCSIAGII THTGASGNAF VACGGT 

« Hide

References

[1]"Isolation, analysis of amino acid sequence and crystallization of the extracellular ribonuclease Th1 from Trichoderma harzianum-01."
Bezborodova S.I., Vasileva-Tonkova E.S., Polyakov K.M., Shlyapnikov S.V.
Bioorg. Khim. 14:453-466(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Strain: 01.

Cross-references

Sequence databases

PIRJN0428.

3D structure databases

ProteinModelPortalP26875.
SMRP26875. Positions 4-106.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.10.450.30. 1 hit.
InterProIPR000026. Gua-sp_ribonuclease_N1/T1.
IPR016191. Ribonuclease/ribotoxin.
[Graphical view]
PfamPF00545. Ribonuclease. 1 hit.
[Graphical view]
SUPFAMSSF53933. SSF53933. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNT1_TRIHA
AccessionPrimary (citable) accession number: P26875
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families