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P26858 (COX3_MARPO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3
Synonyms:COXIII
Encoded onMitochondrion
OrganismMarchantia polymorpha (Liverwort) (Marchantia aquatica)
Taxonomic identifier3197 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaMarchantiophytaMarchantiopsidaMarchantiidaeMarchantialesMarchantiaceaeMarchantia

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 265265Cytochrome c oxidase subunit 3
PRO_0000183807

Regions

Transmembrane16 – 3621Helical; Potential
Transmembrane41 – 6121Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane138 – 15821Helical; Potential
Transmembrane162 – 18221Helical; Potential
Transmembrane200 – 22021Helical; Potential
Transmembrane242 – 26221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P26858 [UniParc].

Last modified October 1, 1993. Version 2.
Checksum: 43D1CC7820C7E7EC

FASTA26529,595
        10         20         30         40         50         60 
MSVSQKHPFH LVDPSPWPLL GSLGALASTI GGVMYMHSFT GGGTLLCLGL GMILYTMFVW 

        70         80         90        100        110        120 
WRDVIRESTY EGHHTFVVQL GLRYGIILFI VSEVMFFLAF FWAFFHSSLA PTVEIGAIWP 

       130        140        150        160        170        180 
PKGISVLDPW GIPFLNTLIL LSSGAAVTWA HHAILAGLKQ QAVYALIATV FLALVFTGFQ 

       190        200        210        220        230        240 
GIEYIEAPFT ISDGIYGSTF FLATGFHGFH VIIGTIFLII CGIRQYLGHF TPKHHFGFEA 

       250        260 
AAFYWHFVDV VWLFLFVSIY WWGGN 

« Hide

References

[1]"Gene organization deduced from the complete sequence of liverwort Marchantia polymorpha mitochondrial DNA. A primitive form of plant mitochondrial genome."
Oda K., Yamato K., Ohta E., Nakamura Y., Takemura M., Nozato N., Akashi K., Kanegae T., Ogura Y., Kohchi T., Ohyama K.
J. Mol. Biol. 223:1-7(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M68929 Genomic DNA. Translation: AAC09434.1.
PIRS25951.
RefSeqNP_054437.1. NC_001660.1.

3D structure databases

ProteinModelPortalP26858.
SMRP26858. Positions 5-263.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2702480.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_MARPO
AccessionPrimary (citable) accession number: P26858
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: October 1, 1993
Last modified: April 16, 2014
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families