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P26858

- COX3_MARPO

UniProt

P26858 - COX3_MARPO

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Protein
Cytochrome c oxidase subunit 3
Gene
COX3, COXIII
Organism
Marchantia polymorpha (Liverwort) (Marchantia aquatica)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COX3
Synonyms:COXIII
Encoded oniMitochondrion
OrganismiMarchantia polymorpha (Liverwort) (Marchantia aquatica)
Taxonomic identifieri3197 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaMarchantiophytaMarchantiopsidaMarchantiidaeMarchantialesMarchantiaceaeMarchantia

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei16 – 3621Helical; Reviewed prediction
Add
BLAST
Transmembranei41 – 6121Helical; Reviewed prediction
Add
BLAST
Transmembranei85 – 10521Helical; Reviewed prediction
Add
BLAST
Transmembranei138 – 15821Helical; Reviewed prediction
Add
BLAST
Transmembranei162 – 18221Helical; Reviewed prediction
Add
BLAST
Transmembranei200 – 22021Helical; Reviewed prediction
Add
BLAST
Transmembranei242 – 26221Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 265265Cytochrome c oxidase subunit 3
PRO_0000183807Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP26858.
SMRiP26858. Positions 5-263.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P26858-1 [UniParc]FASTAAdd to Basket

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MSVSQKHPFH LVDPSPWPLL GSLGALASTI GGVMYMHSFT GGGTLLCLGL    50
GMILYTMFVW WRDVIRESTY EGHHTFVVQL GLRYGIILFI VSEVMFFLAF 100
FWAFFHSSLA PTVEIGAIWP PKGISVLDPW GIPFLNTLIL LSSGAAVTWA 150
HHAILAGLKQ QAVYALIATV FLALVFTGFQ GIEYIEAPFT ISDGIYGSTF 200
FLATGFHGFH VIIGTIFLII CGIRQYLGHF TPKHHFGFEA AAFYWHFVDV 250
VWLFLFVSIY WWGGN 265
Length:265
Mass (Da):29,595
Last modified:October 1, 1993 - v2
Checksum:i43D1CC7820C7E7EC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M68929 Genomic DNA. Translation: AAC09434.1.
PIRiS25951.
RefSeqiNP_054437.1. NC_001660.1.

Genome annotation databases

GeneIDi2702480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M68929 Genomic DNA. Translation: AAC09434.1 .
PIRi S25951.
RefSeqi NP_054437.1. NC_001660.1.

3D structure databases

ProteinModelPortali P26858.
SMRi P26858. Positions 5-263.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2702480.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Gene organization deduced from the complete sequence of liverwort Marchantia polymorpha mitochondrial DNA. A primitive form of plant mitochondrial genome."
    Oda K., Yamato K., Ohta E., Nakamura Y., Takemura M., Nozato N., Akashi K., Kanegae T., Ogura Y., Kohchi T., Ohyama K.
    J. Mol. Biol. 223:1-7(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiCOX3_MARPO
AccessioniPrimary (citable) accession number: P26858
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: October 1, 1993
Last modified: September 3, 2014
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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