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P26783 (RS5_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 127. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
40S ribosomal protein S5
Alternative name(s):
RP14
S2
YS8
Gene names
Name:RPS5
Synonyms:RPS2
Ordered Locus Names:YJR123W
ORF Names:J2045
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length225 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.6

Subcellular location

Cytoplasm By similarity.

Post-translational modification

N-terminally acetylated by acetyltransferase NatA. Ref.5 Ref.7

Sequence similarities

Belongs to the ribosomal protein S7P family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

BUL1P485243EBI-16150,EBI-3881

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.5 Ref.7
Chain2 – 22522440S ribosomal protein S5
PRO_0000124540

Amino acid modifications

Modified residue21N-acetylserine Ref.5 Ref.7
Modified residue271Phosphothreonine Ref.8

Experimental info

Sequence conflict211T → E AA sequence Ref.5

Secondary structure

.................................... 225
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P26783 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: CD3F743B56CB1127

FASTA22525,039
        10         20         30         40         50         60 
MSDTEAPVEV QEDFEVVEEF TPVVLATPIP EEVQQAQTEI KLFNKWSFEE VEVKDASLVD 

        70         80         90        100        110        120 
YVQVRQPIFV AHTAGRYANK RFRKAQCPII ERLTNSLMMN GRNNGKKLKA VRIIKHTLDI 

       130        140        150        160        170        180 
INVLTDQNPI QVVVDAITNT GPREDTTRVG GGGAARRQAV DVSPLRRVNQ AIALLTIGAR 

       190        200        210        220 
EAAFRNIKTI AETLAEELIN AAKGSSTSYA IKKKDELERV AKSNR 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and characterisation of the gene encoding the ribosomal protein S5 (also known as rp14, S2, YS8) of Saccharomyces cerevisiae."
Ignatovich O., Cooper M., Kulesza H.M., Beggs J.D.
Nucleic Acids Res. 23:4616-4619(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"NH2-terminal acetylation of ribosomal proteins of Saccharomyces cerevisiae."
Takakura H., Tsunasawa S., Miyagi M., Warner J.R.
J. Biol. Chem. 267:5442-5445(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-21, ACETYLATION AT SER-2 BY NATA.
[6]"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
Planta R.J., Mager W.H.
Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE, SUBUNIT.
[7]"The action of N-terminal acetyltransferases on yeast ribosomal proteins."
Arnold R.J., Polevoda B., Reilly J.P., Sherman F.
J. Biol. Chem. 274:37035-37040(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT SER-2 BY NATA.
[8]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-27, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[9]"Sites of ubiquitin attachment in Saccharomyces cerevisiae."
Starita L.M., Lo R.S., Eng J.K., von Haller P.D., Fields S.
Proteomics 12:236-240(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[10]"Structure of the 80S ribosome from Saccharomyces cerevisiae -- tRNA-ribosome and subunit-subunit interactions."
Spahn C.M.T., Beckmann R., Eswar N., Penczek P.A., Sali A., Blobel G., Frank J.
Cell 107:373-386(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: 3D-STRUCTURE MODELING OF 76-225, ELECTRON MICROSCOPY.
[11]"Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation."
Spahn C.M.T., Gomez-Lorenzo M.G., Grassucci R.A., Joergensen R., Andersen G.R., Beckmann R., Penczek P.A., Ballesta J.P.G., Frank J.
EMBO J. 23:1008-1019(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: 3D-STRUCTURE MODELING OF 76-225, ELECTRON MICROSCOPY.
[12]"Structure of the ribosome-bound cricket paralysis virus IRES RNA."
Schueler M., Connell S.R., Lescoute A., Giesebrecht J., Dabrowski M., Schroeer B., Mielke T., Penczek P.A., Westhof E., Spahn C.M.T.
Nat. Struct. Mol. Biol. 13:1092-1096(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY ELECTRON MICROSCOPY (7.3 ANGSTROMS) OF 76-225.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X89368 Genomic DNA. Translation: CAA61550.1.
Z49623 Genomic DNA. Translation: CAA89654.1.
AY692868 Genomic DNA. Translation: AAT92887.1.
BK006943 Genomic DNA. Translation: DAA08908.1.
PIRS55720.
RefSeqNP_012657.1. NM_001181781.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1K5Xmodel-G76-225[»]
1S1Helectron microscopy11.70G76-225[»]
2NOQelectron microscopy7.30F76-225[»]
3IZBelectron microscopy-F1-225[»]
3O2ZX-ray4.00D1-225[»]
3O30X-ray4.00D1-225[»]
3U5CX-ray3.00F1-225[»]
3U5GX-ray3.00F1-225[»]
4BYLelectron microscopy4.30F1-225[»]
4BYTelectron microscopy6.60F1-225[»]
ProteinModelPortalP26783.
SMRP26783. Positions 20-225.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33879. 157 interactions.
DIPDIP-5092N.
IntActP26783. 66 interactions.
MINTMINT-480795.
STRING4932.YJR123W.

2D gel databases

UCD-2DPAGEP26783.

Proteomic databases

PaxDbP26783.
PeptideAtlasP26783.
PRIDEP26783.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJR123W; YJR123W; YJR123W.
GeneID853587.
KEGGsce:YJR123W.

Organism-specific databases

SGDS000003884. RPS5.

Phylogenomic databases

eggNOGCOG0049.
GeneTreeENSGT00390000010806.
HOGENOMHOG000039066.
KOK02989.
OMAPREETTR.
OrthoDBEOG7MD52N.

Enzyme and pathway databases

BioCycYEAST:G3O-31744-MONOMER.

Gene expression databases

GenevestigatorP26783.

Family and domain databases

Gene3D1.10.455.10. 1 hit.
InterProIPR000235. Ribosomal_S5/S7.
IPR005716. Ribosomal_S5/S7_euk/arc.
IPR020606. Ribosomal_S7_CS.
IPR023798. Ribosomal_S7_dom.
[Graphical view]
PANTHERPTHR11205. PTHR11205. 1 hit.
PfamPF00177. Ribosomal_S7. 1 hit.
[Graphical view]
SUPFAMSSF47973. SSF47973. 1 hit.
TIGRFAMsTIGR01028. S7_S5_E_A. 1 hit.
PROSITEPS00052. RIBOSOMAL_S7. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP26783.
NextBio974388.
PROP26783.

Entry information

Entry nameRS5_YEAST
AccessionPrimary (citable) accession number: P26783
Secondary accession number(s): D6VWU2
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: January 23, 2007
Last modified: March 19, 2014
This is version 127 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references