P26686 (SRR55_DROME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Serine-arginine protein 55
Short name=SRP55

Alternative name(s):
52 kDa bracketing protein
B52 protein
Protein enhancer of deformed

Gene names

Name:	B52
Synonyms:	E(Dfd), RS55, SR55
ORF Names:	CG10851

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Essential for development. May have a critical role in splicing or in controlling alternative splice site use of at least some pre-mRNA in vivo. Not required for all splicing. May play a general role in the condensation or decondensation of chromatin. Ref.1 Ref.8 Ref.9
Subcellular location	Nucleus. Note: Associated with boundaries of transcriptionally active chromatin. Ref.1 Ref.2 Ref.8
Developmental stage	Expressed throughout development. Ref.9
Post-translational modification	Extensively phosphorylated on serine residues in the RS domain. Ref.1 Ref.10
Sequence similarities	Belongs to the splicing factor SR family. Contains 2 RRM (RNA recognition motif) domains.
Sequence caution	The sequence AAN71237.1 differs from that shown. Reason: Frameshift at position 78.

Ontologies

Keywords
Biological process	mRNA processing mRNA splicing
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Domain	Repeat
Ligand	RNA-binding
PTM	Phosphoprotein
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological process	mitosis Inferred from mutant phenotype. Source: FlyBase nuclear mRNA splicing, via spliceosome Inferred from direct assay. Source: FlyBase regulation of alternative nuclear mRNA splicing, via spliceosome Inferred from mutant phenotype. Source: FlyBase
Cellular component	catalytic step 2 spliceosome Inferred from direct assay. Source: FlyBase nuclear speck Inferred from direct assay. Source: FlyBase polytene chromosome Inferred from direct assay. Source: FlyBase precatalytic spliceosome Inferred from direct assay. Source: FlyBase
Molecular function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: FlyBase
Complete GO annotation...

Alternative products

This entry describes 9 isoforms produced by alternative splicing. [Align] [Select]

Isoform Long (identifier: P26686-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform A (identifier: P26686-2)

Also known as: C;

The sequence of this isoform differs from the canonical sequence as follows:
     103-107: Missing.
     319-339: Missing.

Isoform B (identifier: P26686-3)

Also known as: I;

The sequence of this isoform differs from the canonical sequence as follows:
     323-376: SFKSSFYKFTTMPFFCSDRSASAENKSRSRSRSRSASPKNGNASPDRNNESMDD → VVQKLVL

Note: No experimental confirmation available.

Isoform D (identifier: P26686-4)

The sequence of this isoform differs from the canonical sequence as follows:
     103-107: Missing.
     135-140: DLKDYM → SLMCFD
     141-376: Missing.

Note: No experimental confirmation available.

Isoform E (identifier: P26686-5)

The sequence of this isoform differs from the canonical sequence as follows:
     319-339: Missing.

Note: No experimental confirmation available.

Isoform F (identifier: P26686-6)

Also known as: K;

The sequence of this isoform differs from the canonical sequence as follows:
     103-107: Missing.
     135-152: DLKDYMRQAGEVTYADAH → VSEHGSMYRALGVVYTVA
     153-376: Missing.

Note: No experimental confirmation available.

Isoform G (identifier: P26686-7)

Also known as: H;

The sequence of this isoform differs from the canonical sequence as follows:
     1-139: Missing.
     319-339: Missing.

Note: No experimental confirmation available.

Isoform J (identifier: P26686-8)

The sequence of this isoform differs from the canonical sequence as follows:
     78-261: Missing.
     319-339: Missing.

Note: No experimental confirmation available.

Isoform L (identifier: P26686-9)

The sequence of this isoform differs from the canonical sequence as follows:
     103-107: Missing.
     132-154: SWQDLKDYMRQAGEVTYADAHKQ → RSQGLHAPGWRGHLCRCPQAASQ
     155-376: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.1
	Chain	2 – 376	375	Serine-arginine protein 55		PRO_0000081961
Regions
	Domain	4 – 74	71	RRM 1
	Domain	120 – 193	74	RRM 2
	Compositional bias	89 – 97	9	Gly-rich (hinge region)
	Compositional bias	184 – 359	176	Arg/Ser-rich (RS domain)
Amino acid modifications
	Modified residue	165	1	Phosphoserine Ref.10
Natural variations
	Alternative sequence	1 – 139	139	Missing in isoform G.		VSP_015924
	Alternative sequence	78 – 261	184	Missing in isoform J.		VSP_015925
	Alternative sequence	103 – 107	5	Missing in isoform A, isoform D, isoform F and isoform L.		VSP_015926
	Alternative sequence	132 – 154	23	SWQDL…DAHKQ → RSQGLHAPGWRGHLCRCPQA ASQ in isoform L.		VSP_041738
	Alternative sequence	135 – 152	18	DLKDY…YADAH → VSEHGSMYRALGVVYTVA in isoform F.		VSP_015928
	Alternative sequence	135 – 140	6	DLKDYM → SLMCFD in isoform D.		VSP_015929
	Alternative sequence	141 – 376	236	Missing in isoform D.		VSP_015930
	Alternative sequence	153 – 376	224	Missing in isoform F.		VSP_015931
	Alternative sequence	155 – 376	222	Missing in isoform L.		VSP_041739
	Alternative sequence	319 – 339	21	Missing in isoform A, isoform E, isoform G and isoform J.		VSP_005878
	Alternative sequence	323 – 376	54	SFKSS…ESMDD → VVQKLVL in isoform B.		VSP_015932
Experimental info
	Sequence conflict	7	1	Y → F in AAB24629. Ref.7
	Sequence conflict	17 – 18	2	ER → AA in AAB24629. Ref.7
	Sequence conflict	40 – 42	3	GFV → AFM in AAB24629. Ref.7
	Sequence conflict	75	1	T → S in CAA41556. Ref.1
	Sequence conflict	196	1	R → A in CAA44483. Ref.2
	Sequence conflict	229	1	S → T in CAA44483. Ref.2
	Sequence conflict	261	1	R → A in CAA44483. Ref.2
	Sequence conflict	280 – 282	3	RSR → APV in CAA44483. Ref.2
	Sequence conflict	294	1	S → T in CAA41556. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform Long [UniParc]. Last modified January 23, 2007. Version 4. Checksum: B35CEDA034933019	FASTA	376	42,813
	10 20 30 40 50 60 MVGSRVYVGG LPYGVRERDL ERFFKGYGRT RDILIKNGYG FVEFEDYRDA DDAVYELNGK 70 80 90 100 110 120 ELLGERVVVE PARGTARGSN RDRYDDRYGG RRGGGGGRYN EKNKNSRSSS RYGPPLRTEY 130 140 150 160 170 180 RLIVENLSSR VSWQDLKDYM RQAGEVTYAD AHKQRRNEGV VEFASLSDMK TAIEKLDDTE 190 200 210 220 230 240 LNGRRIHLVE DRRGGRSGGG GGSGRGRSRS SSSRSRSRSR RRSRSRRSSH SRSKSRSRSK 250 260 270 280 290 300 SRGGRSKSKS PVKSRSRSRS RSNKSRDVSK SKSKSHSRTR SRSPKRERDS RSRSRSVSKR 310 320 330 340 350 360 ESRSRSRSKS IHRDSRSRPP TVSFKSSFYK FTTMPFFCSD RSASAENKSR SRSRSRSASP 370 KNGNASPDRN NESMDD
	Isoform A (C) [UniParc]. Checksum: 7EDD2BC7FC52F865	FASTA	350	39,782
	10 20 30 40 50 60 MVGSRVYVGG LPYGVRERDL ERFFKGYGRT RDILIKNGYG FVEFEDYRDA DDAVYELNGK 70 80 90 100 110 120 ELLGERVVVE PARGTARGSN RDRYDDRYGG RRGGGGGRYN EKSSSRYGPP LRTEYRLIVE 130 140 150 160 170 180 NLSSRVSWQD LKDYMRQAGE VTYADAHKQR RNEGVVEFAS LSDMKTAIEK LDDTELNGRR 190 200 210 220 230 240 IHLVEDRRGG RSGGGGGSGR GRSRSSSSRS RSRSRRRSRS RRSSHSRSKS RSRSKSRGGR 250 260 270 280 290 300 SKSKSPVKSR SRSRSRSNKS RDVSKSKSKS HSRTRSRSPK RERDSRSRSR SVSKRESRSR 310 320 330 340 350 SRSKSIHRDS RSRDRSASAE NKSRSRSRSR SASPKNGNAS PDRNNESMDD
	Isoform B (I) [UniParc]. Checksum: 7BD8602770AEF24A	FASTA	329	37,536
	10 20 30 40 50 60 MVGSRVYVGG LPYGVRERDL ERFFKGYGRT RDILIKNGYG FVEFEDYRDA DDAVYELNGK 70 80 90 100 110 120 ELLGERVVVE PARGTARGSN RDRYDDRYGG RRGGGGGRYN EKNKNSRSSS RYGPPLRTEY 130 140 150 160 170 180 RLIVENLSSR VSWQDLKDYM RQAGEVTYAD AHKQRRNEGV VEFASLSDMK TAIEKLDDTE 190 200 210 220 230 240 LNGRRIHLVE DRRGGRSGGG GGSGRGRSRS SSSRSRSRSR RRSRSRRSSH SRSKSRSRSK 250 260 270 280 290 300 SRGGRSKSKS PVKSRSRSRS RSNKSRDVSK SKSKSHSRTR SRSPKRERDS RSRSRSVSKR 310 320 ESRSRSRSKS IHRDSRSRPP TVVVQKLVL
	Isoform D [UniParc]. Checksum: CF9FEC836310B725	FASTA	135	15,469
	10 20 30 40 50 60 MVGSRVYVGG LPYGVRERDL ERFFKGYGRT RDILIKNGYG FVEFEDYRDA DDAVYELNGK 70 80 90 100 110 120 ELLGERVVVE PARGTARGSN RDRYDDRYGG RRGGGGGRYN EKSSSRYGPP LRTEYRLIVE 130 NLSSRVSWQS LMCFD
	Isoform E [UniParc]. Checksum: 54A1776E1F85A095	FASTA	355	40,381
	10 20 30 40 50 60 MVGSRVYVGG LPYGVRERDL ERFFKGYGRT RDILIKNGYG FVEFEDYRDA DDAVYELNGK 70 80 90 100 110 120 ELLGERVVVE PARGTARGSN RDRYDDRYGG RRGGGGGRYN EKNKNSRSSS RYGPPLRTEY 130 140 150 160 170 180 RLIVENLSSR VSWQDLKDYM RQAGEVTYAD AHKQRRNEGV VEFASLSDMK TAIEKLDDTE 190 200 210 220 230 240 LNGRRIHLVE DRRGGRSGGG GGSGRGRSRS SSSRSRSRSR RRSRSRRSSH SRSKSRSRSK 250 260 270 280 290 300 SRGGRSKSKS PVKSRSRSRS RSNKSRDVSK SKSKSHSRTR SRSPKRERDS RSRSRSVSKR 310 320 330 340 350 ESRSRSRSKS IHRDSRSRDR SASAENKSRS RSRSRSASPK NGNASPDRNN ESMDD
	Isoform F (K) [UniParc]. Checksum: A951ABAE25029D00	FASTA	147	16,694
	10 20 30 40 50 60 MVGSRVYVGG LPYGVRERDL ERFFKGYGRT RDILIKNGYG FVEFEDYRDA DDAVYELNGK 70 80 90 100 110 120 ELLGERVVVE PARGTARGSN RDRYDDRYGG RRGGGGGRYN EKSSSRYGPP LRTEYRLIVE 130 140 NLSSRVSWQV SEHGSMYRAL GVVYTVA
	Isoform G (H) [UniParc]. Checksum: 8A372A38D2E8D51C	FASTA	216	24,393
	10 20 30 40 50 60 MRQAGEVTYA DAHKQRRNEG VVEFASLSDM KTAIEKLDDT ELNGRRIHLV EDRRGGRSGG 70 80 90 100 110 120 GGGSGRGRSR SSSSRSRSRS RRRSRSRRSS HSRSKSRSRS KSRGGRSKSK SPVKSRSRSR 130 140 150 160 170 180 SRSNKSRDVS KSKSKSHSRT RSRSPKRERD SRSRSRSVSK RESRSRSRSK SIHRDSRSRD 190 200 210 RSASAENKSR SRSRSRSASP KNGNASPDRN NESMDD
	Isoform J [UniParc]. Checksum: F94FBC33C8A00A14	FASTA	171	19,554
	10 20 30 40 50 60 MVGSRVYVGG LPYGVRERDL ERFFKGYGRT RDILIKNGYG FVEFEDYRDA DDAVYELNGK 70 80 90 100 110 120 ELLGERVVVE PARGTARSNK SRDVSKSKSK SHSRTRSRSP KRERDSRSRS RSVSKRESRS 130 140 150 160 170 RSRSKSIHRD SRSRDRSASA ENKSRSRSRS RSASPKNGNA SPDRNNESMD D
	Isoform L [UniParc]. Checksum: 9779F973085E8639	FASTA	149	16,870
	10 20 30 40 50 60 MVGSRVYVGG LPYGVRERDL ERFFKGYGRT RDILIKNGYG FVEFEDYRDA DDAVYELNGK 70 80 90 100 110 120 ELLGERVVVE PARGTARGSN RDRYDDRYGG RRGGGGGRYN EKSSSRYGPP LRTEYRLIVE 130 140 NLSSRVRSQG LHAPGWRGHL CRCPQAASQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription." Roth M.B., Zahler A.M., Stolk J.A. J. Cell Biol. 115:587-596(1991) [PubMed: 1717489] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A), PROTEIN SEQUENCE OF 2-15; 126-132 AND 137-148, FUNCTION, SUBCELLULAR LOCATION, PHOSPHORYLATION. Strain: CL. Tissue: Embryo.
[2]	"Characterization of a Drosophila protein associated with boundaries of transcriptionally active chromatin." Champlin D.T., Frasch M., Saumweber H., Lis J.T. Genes Dev. 5:1611-1621(1991) [PubMed: 1885003] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG), SUBCELLULAR LOCATION. Tissue: Embryo.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[4]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: GENOME REANNOTATION, ALTERNATIVE SPLICING. Strain: Berkeley.
[5]	"A Drosophila full-length cDNA resource." Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E. Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS A AND G), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 4-376 (ISOFORM J). Strain: Berkeley. Tissue: Embryo, Head and Testis.
[6]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.W., Booth B., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R.A., Gonzalez M., Guarin H., Kronmiller B., Li P.W., Liao G. , Miranda A., Mungall C.J., Nunoo J., Pacleb J.M., Paragas V., Park S., Patel S., Phouanenavong S., Wan K.H., Yu C., Lewis S.E., Rubin G.M., Celniker S.E. Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS A; E; G AND J). Strain: Berkeley. Tissue: Head and Ovary.
[7]	"Isolation of RRM-type RNA-binding protein genes and the analysis of their relatedness by using a numerical approach." Kim Y.-J., Baker B.S. Mol. Cell. Biol. 13:174-183(1993) [PubMed: 8417324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 7-42.
[8]	"Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing." Mayeda A., Zahler A.M., Krainer A.R., Roth M.B. Proc. Natl. Acad. Sci. U.S.A. 89:1301-1304(1992) [PubMed: 1741384] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION.
[9]	"The SR protein B52/SRp55 is essential for Drosophila development." Ring H.Z., Lis J.T. Mol. Cell. Biol. 14:7499-7506(1994) [PubMed: 7935465] [Abstract] Cited for: FUNCTION, DEVELOPMENTAL STAGE.
[10]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-165, MASS SPECTROMETRY. Tissue: Embryo.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X58720 mRNA. Translation: CAA41556.1. X62599 mRNA. Translation: CAA44483.1. AE014297 Genomic DNA. Translation: AAF54968.1. AE014297 Genomic DNA. Translation: AAF54969.2. AE014297 Genomic DNA. Translation: AAN13575.1. AE014297 Genomic DNA. Translation: AAN13577.1. AE014297 Genomic DNA. Translation: AAN13578.1. AE014297 Genomic DNA. Translation: ACZ94900.1. AE014297 Genomic DNA. Translation: ACZ94901.1. AE014297 Genomic DNA. Translation: ACZ94902.1. AY069302 mRNA. Translation: AAL39447.1. AY113327 mRNA. Translation: AAM29332.1. BT001417 mRNA. Translation: AAN71172.1. BT001482 mRNA. Translation: AAN71237.1. Frameshift. BT001495 mRNA. Translation: AAN71250.1. BT001750 mRNA. Translation: AAN71505.1. BT003286 mRNA. Translation: AAO25044.1. BT004500 mRNA. Translation: AAO42664.1. BT125783 mRNA. Translation: ADQ89797.1. S51722 mRNA. Translation: AAB24629.1.
PIR	A37282. A40459. H48110.
RefSeq	NP_001163603.1. NM_001170132.1. NP_001163604.1. NM_001170133.1. NP_001163605.1. NM_001170134.1. NP_788665.1. NM_176488.2. NP_788666.1. NM_176489.2. NP_788668.1. NM_176491.2. NP_788669.1. NM_176492.3. NP_788670.1. NM_176493.3.
UniGene	Dm.2188.
3D structure databases
ProteinModelPortal	P26686.
SMR	P26686. Positions 4-192.
ModBase	Search...
Protein-protein interaction databases
IntAct	P26686. 3 interactions.
MINT	MINT-934286.
STRING	P26686.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	41670.
KEGG	dme:Dmel_CG10851.
Organism-specific databases
CTD	41670.
FlyBase	FBgn0004587. B52.
Phylogenomic databases
eggNOG	inNOG06535.
GeneTree	EMGT00050000000447.
InParanoid	P26686.
OMA	DRNNESM.
OrthoDB	EOG4NK9C3.
PhylomeDB	P26686.
Gene expression databases
Bgee	P26686.
GermOnline	CG10851. Drosophila melanogaster.
Family and domain databases
InterPro	IPR012677. Nucleotide-bd_a/b_plait. IPR000504. RRM_dom. [Graphical view]
Gene3D	G3DSA:3.30.70.330. a_b_plait_nuc_bd. 2 hits.
KO	K12893.
Pfam	PF00076. RRM_1. 2 hits. [Graphical view]
SMART	SM00360. RRM. 2 hits. [Graphical view]
PROSITE	PS50102. RRM. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	824942.

Entry information

Entry name

SRR55_DROME

Accession

Primary (citable) accession number: P26686
Secondary accession number(s): A4V2U2 , E1JIK1, E1JIK2, E1JIK3, E4NKI6, Q24252, Q26277, Q8IH12, Q8ING7, Q8ING8, Q8ING9, Q8MZ66, Q8T0I0, Q9VFT0, Q9VFT1

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	January 23, 2007
Last modified:	January 25, 2012
This is version 118 of the entry and version 4 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project