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Protein

Non-structural protein 2a

Gene

2a

Organism
Murine coronavirus (strain JHM) (MHV-JHM) (Murine hepatitis virus)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Not essential for virus replication in transformed murine cells.

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein 2a
Short name:
ns2a
Alternative name(s):
30 kDa accessory protein
30 kDa non-structural protein
ns2
p30
Gene namesi
ORF Names:2a
OrganismiMurine coronavirus (strain JHM) (MHV-JHM) (Murine hepatitis virus)
Taxonomic identifieri11144 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageNidoviralesCoronaviridaeCoronavirinaeBetacoronavirus
Virus hostiMus musculus (Mouse) [TaxID: 10090]
Proteomesi
  • UP000007193 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001060611 – 265Non-structural protein 2aAdd BLAST265

Proteomic databases

PRIDEiP26625.

Structurei

3D structure databases

ProteinModelPortaliP26625.
SMRiP26625.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the coronaviruses ns2a protein family.Curated

Phylogenomic databases

OrthoDBiVOG090000HA.

Family and domain databases

InterProiView protein in InterPro
IPR009097. cNuc_Pdiesterase.
IPR007878. Coronavirus_NS2A.
PIRSFiPIRSF003890. LigT_coronavirus. 1 hit.
SUPFAMiSSF55144. SSF55144. 1 hit.

Sequencei

Sequence statusi: Complete.

P26625-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARMAFADK PNHFINFPLA QFSGFMGKYL KLQSQLVEMG LDCKLQKVPH
60 70 80 90 100
VSITLLDIKA DQYKQVEFAI QEIIDDLAAY EGDIVFDNPH MLGRCLVLDV
110 120 130 140 150
KGFEELHEDI VEILRRRGCT ADQSRQWIPH CTVAQFDEEK EIKEMQFYFK
160 170 180 190 200
LPFYLKHNNL LTDARLELVK IGSSKVGGFY CSELSIWCGE RLCYKPPTPK
210 220 230 240 250
FSDIFGYCCI DKIRGDLEIG DLPPDDEEAW AELSYHYQRN TYFFRHVHDN
260
SIYFRTVCRM KGCMC
Length:265
Mass (Da):30,874
Last modified:August 1, 1992 - v1
Checksum:i8B1C66E28D9AE95B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti177G → D in AAA46441 (PubMed:2547994).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34035 Genomic RNA. Translation: AAA46464.1.
M28348 Genomic RNA. Translation: AAA46441.1.
M57954 mRNA. Translation: AAA46463.1.
PIRiA36542. MNIHJH.
RefSeqiYP_209231.1. AC_000192.1.

Similar proteinsi

Entry informationi

Entry nameiNS2A_CVMJH
AccessioniPrimary (citable) accession number: P26625
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: March 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome