Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P26563

- AATM_LUPAN

UniProt

P26563 - AATM_LUPAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Aspartate aminotransferase P2, mitochondrial

Gene
N/A
Organism
Lupinus angustifolius (Narrow-leaved blue lupine)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Important for the metabolism of amino acids and Krebs-cycle related organic acids. In plants, it is involved in nitrogen metabolism and in aspects of carbon and energy metabolism.

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

Cofactori

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei86 – 861Aspartate; via amide nitrogenBy similarity
Binding sitei182 – 1821AspartateBy similarity
Binding sitei235 – 2351AspartateBy similarity
Binding sitei428 – 4281AspartateBy similarity

GO - Molecular functioni

  1. L-aspartate:2-oxoglutarate aminotransferase activity Source: UniProtKB
  2. L-phenylalanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  3. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. 2-oxoglutarate metabolic process Source: UniProtKB
  2. aspartate metabolic process Source: UniProtKB
  3. biosynthetic process Source: InterPro
  4. glutamate metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Keywords - Ligandi

Pyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferase P2, mitochondrial (EC:2.6.1.1)
Alternative name(s):
Transaminase A
OrganismiLupinus angustifolius (Narrow-leaved blue lupine)
Taxonomic identifieri3871 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeGenisteaeLupinus

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei‹1 – 49›49MitochondrionSequence AnalysisAdd
BLAST
Chaini50 – 454405Aspartate aminotransferase P2, mitochondrialPRO_0000001212Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei299 – 2991N6-(pyridoxal phosphate)lysineBy similarity

Proteomic databases

PRIDEiP26563.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP26563.
SMRiP26563. Positions 52-448.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P26563-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
SSLLSIPSLS LQYNDKLKVG GNSLRFSKEQ SNTFSNAKSS CRISMVAAVN
60 70 80 90 100
VSRFEGIPMA PPDPILGVSE AFRADTSDAK LNLGVGAYRT EELQPYVLKV
110 120 130 140 150
VNKAENLMLE RGQNKEYLAI EGLAAFNKAT AELLLGADNP AIKQQRVATV
160 170 180 190 200
QGLSGTGSLR LGAALIERYF PGAKVLISAP TWGNHKNIFN DARVPWSEYR
210 220 230 240 250
YYDPKTVGLD FEGMIEDIKA APEGTFVLLH GCAHNPTGID PTPEQWEKIA
260 270 280 290 300
DVIQEKNHIP FFDVAYQGFA SGSLDEDAAS VRLFVARGLE VLVAQSYSKN
310 320 330 340 350
LGLYAERIGA INVISSSPES AARVKSQLKR IARPMYSNPP VHGARIVADI
360 370 380 390 400
VGNPALFDEW KVEMEMMAGR IKNVRQQLYD SISSKDKSGK DWSFILKQIG
410 420 430 440 450
MFSYTGLNKN QSDNMTNKWH VYMTKDGRIS LAGLSLAKCE YLADAIIDSF

HYVS
Length:454
Mass (Da):49,916
Last modified:August 1, 1992 - v1
Checksum:i744CC12F1D81E739
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59761 mRNA. Translation: CAA42430.1.
PIRiS22465. XNYLB.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59761 mRNA. Translation: CAA42430.1 .
PIRi S22465. XNYLB.

3D structure databases

ProteinModelPortali P26563.
SMRi P26563. Positions 52-448.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P26563.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11879. PTHR11879. 1 hit.
Pfami PF00155. Aminotran_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00799. TRANSAMINASE.
SUPFAMi SSF53383. SSF53383. 1 hit.
PROSITEi PS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning of a cDNA encoding aspartate aminotransferase-P2 from lupin root nodules."
    Reynolds P.H.S., Smith L.A., Jones W.T., Dickson J.M.J., Jones S.J., Rodber K., Liddane C.P.
    Plant Mol. Biol. 19:465-472(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Uniharvest.
    Tissue: Root nodule.

Entry informationi

Entry nameiAATM_LUPAN
AccessioniPrimary (citable) accession number: P26563
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: November 26, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3