P26533 (ATPE_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATP synthase epsilon chain

Alternative name(s):
ATP synthase F1 sector epsilon subunit
F-ATPase epsilon subunit

Gene names

Name:	atpC
Synonyms:	atpE
Ordered Locus Names:	slr1330

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › Synechocystis sp. PCC 6803

Protein attributes

Sequence length	136 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. HAMAP-Rule MF_00530
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.
Subcellular location	Cellular thylakoid membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_00530.
Sequence similarities	Belongs to the ATPase epsilon chain family.
Sequence caution	The sequence BAA18088.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Membrane Thylakoid
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	plasma membrane ATP synthesis coupled proton transport Inferred from electronic annotation. Source: HAMAP
Cellular_component	plasma membrane proton-transporting ATP synthase complex Inferred from direct assay PubMed 14730074. Source: UniProtKB proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP proton-transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.3
	Chain	2 – 136	135	ATP synthase epsilon chain HAMAP-Rule MF_00530		PRO_0000188230

Sequences

	Sequence		Length	Mass (Da)
	P26533 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 55B8F3545DC23E72	FASTA	136	14,581
	10 20 30 40 50 60 MTLTVRVITP DKVVWDEEVQ ELILPSTTGQ LGILSNHAPL LTALEIGVMR VRPGKDWQNI 70 80 90 100 110 120 AVMGGFAEVE NNEVKVLVNG AELGTTIDAE SARQAYTAAQ GALEEANRGE DKPNQLKASN 130 NYKKARARLQ AAGGAV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The atp1 and atp2 operons of the cyanobacterium Synechocystis sp. PCC 6803." Lill H., Nelson N. Plant Mol. Biol. 17:641-652(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa.
[3]	"Towards a proteome project of cyanobacterium Synechocystis sp. strain PCC6803: linking 130 protein spots with their respective genes." Sazuka T., Ohara O. Electrophoresis 18:1252-1258(1997) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-21.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X58129 Genomic DNA. Translation: CAA41138.1. BA000022 Genomic DNA. Translation: BAA18088.1. Different initiation.
PIR	S75527.
RefSeq	NP_441408.2. NC_000911.1. YP_005651466.1. NC_017277.1. YP_007451290.1. NC_020286.1.
3D structure databases
ProteinModelPortal	P26533.
ModBase	Search...
Protein-protein interaction databases
IntAct	P26533. 7 interactions.
STRING	1148.slr1330.
Proteomic databases
PaxDb	P26533.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA18088; BAA18088; BAA18088.
GeneID	12254116. 14616948. 954764.
KEGG	syn:slr1330. syy:SYNGTS_1513.
PATRIC	23840213. VBISynSp132158_1666.
Phylogenomic databases
eggNOG	COG0355.
HOGENOM	HOG000216024.
KO	K02114.
OMA	DWVAING.
ProtClustDB	PRK00571.
Family and domain databases
Gene3D	2.60.15.10. 1 hit.
HAMAP	MF_00530. ATP_synth_epsil_bac.
InterPro	IPR001469. ATPase_F1-cplx_dsu/esu. IPR020547. ATPase_F1-cplx_dsu/esu_C. IPR020546. ATPase_F1-cplx_dsu/esu_N. [Graphical view]
PANTHER	PTHR13822. PTHR13822. 1 hit.
Pfam	PF00401. ATP-synt_DE. 1 hit. PF02823. ATP-synt_DE_N. 1 hit. [Graphical view]
ProDom	PD000944. ATPase_F1-cplx_dsu/esu. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF51344. ATPsynt_DE. 1 hit.
TIGRFAMs	TIGR01216. ATP_synt_epsi. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ATPE_SYNY3

Accession

Primary (citable) accession number: P26533

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 99 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program