P26533 (ATPE_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATP synthase epsilon chain

Alternative name(s):
ATP synthase F1 sector epsilon subunit
F-ATPase epsilon subunit

Gene names

Name:	atpC
Synonyms:	atpE
Ordered Locus Names:	slr1330

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	136 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. HAMAP MF_00530
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.
Subcellular location	Cellular thylakoid membrane; Peripheral membrane protein By similarity HAMAP MF_00530.
Sequence similarities	Belongs to the ATPase epsilon chain family.
Sequence caution	The sequence BAA18088.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Membrane Thylakoid
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological process	ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane proton-transporting ATP synthase complex Inferred from direct assay. Source: UniProtKB proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.3
	Chain	2 – 136	135	ATP synthase epsilon chain HAMAP MF_00530		PRO_0000188230

Sequences

	Sequence		Length	Mass (Da)
	P26533 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 55B8F3545DC23E72	FASTA	136	14,581
	10 20 30 40 50 60 MTLTVRVITP DKVVWDEEVQ ELILPSTTGQ LGILSNHAPL LTALEIGVMR VRPGKDWQNI 70 80 90 100 110 120 AVMGGFAEVE NNEVKVLVNG AELGTTIDAE SARQAYTAAQ GALEEANRGE DKPNQLKASN 130 NYKKARARLQ AAGGAV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The atp1 and atp2 operons of the cyanobacterium Synechocystis sp. PCC 6803." Lill H., Nelson N. Plant Mol. Biol. 17:641-652(1991) [PubMed: 1832989] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.
[3]	"Towards a proteome project of cyanobacterium Synechocystis sp. strain PCC6803: linking 130 protein spots with their respective genes." Sazuka T., Ohara O. Electrophoresis 18:1252-1258(1997) [PubMed: 9298645] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-21.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X58129 Genomic DNA. Translation: CAA41138.1. BA000022 Genomic DNA. Translation: BAA18088.1. Different initiation.
PIR	S75527.
RefSeq	NP_441408.2. NC_000911.1.
3D structure databases
ProteinModelPortal	P26533.
ModBase	Search...
Protein-protein interaction databases
IntAct	P26533. 7 interactions.
STRING	P26533.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	954764.
GenomeReviews	Gene locus slr1330 in contig BA000022_GR.
KEGG	syn:slr1330.
NMPDR	fig|1148.1.peg.1509.
PATRIC	23840213. VBISynSp132158_1666.
Phylogenomic databases
eggNOG	COG0355.
HOGENOM	HBG663981.
OMA	DWVAING.
PhylomeDB	P26533.
ProtClustDB	PRK00571.
Enzyme and pathway databases
BioCyc	SSP1148:SLR1330-MONOMER.
Family and domain databases
HAMAP	MF_00530. ATP_synth_epsil_bac. [Tree]
InterPro	IPR001469. ATPase_F1-cplx_dsu/esu. IPR020547. ATPase_F1-cplx_dsu/esu_C. IPR020546. ATPase_F1-cplx_dsu/esu_N. [Graphical view]
Gene3D	G3DSA:2.60.15.10. ATPase_F1_d/e. 1 hit.
KO	K02114.
PANTHER	PTHR13822. ATPase_F1_d/e. 1 hit.
Pfam	PF00401. ATP-synt_DE. 1 hit. PF02823. ATP-synt_DE_N. 1 hit. [Graphical view]
ProDom	PD000944. ATPase_F1-cplx_dsu/esu. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF51344. ATPsynt_DE. 1 hit.
TIGRFAMs	TIGR01216. ATP_synt_epsi. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ATPE_SYNY3

Accession

Primary (citable) accession number: P26533

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	January 23, 2007
Last modified:	January 25, 2012
This is version 87 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program