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P26515

- XYNB_STRLI

UniProt

P26515 - XYNB_STRLI

Protein

Endo-1,4-beta-xylanase B

Gene

xlnB

Organism
Streptomyces lividans
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 3 (14 Aug 2001)
      Previous versions | rss
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    • Comment

    Functioni

    Contributes to hydrolyze hemicellulose, the major component of plant cell-walls. XLNA and XLNB seem to act sequentially on the substrate to yield xylobiose and xylose as carbon sources.

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei128 – 1281NucleophilePROSITE-ProRule annotation
    Active sitei218 – 2181Proton donorPROSITE-ProRule annotation

    GO - Molecular functioni

    1. endo-1,4-beta-xylanase activity Source: UniProtKB-EC
    2. polysaccharide binding Source: InterPro

    GO - Biological processi

    1. xylan catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

    Enzyme and pathway databases

    UniPathwayiUPA00114.

    Protein family/group databases

    CAZyiCBM2. Carbohydrate-Binding Module Family 2.
    GH11. Glycoside Hydrolase Family 11.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endo-1,4-beta-xylanase B (EC:3.2.1.8)
    Short name:
    Xylanase B
    Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase B
    Gene namesi
    Name:xlnB
    OrganismiStreptomyces lividans
    Taxonomic identifieri1916 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 41411 PublicationAdd
    BLAST
    Chaini42 – 335294Endo-1,4-beta-xylanase BPRO_0000008010Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP26515.
    SMRiP26515. Positions 45-228.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini250 – 33586CBM2Add
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni42 – 230189CatalyticAdd
    BLAST
    Regioni231 – 24919Linker ("hinge") (Gly-rich box)Add
    BLAST

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di2.60.120.180. 1 hit.
    2.60.40.290. 1 hit.
    InterProiIPR008965. Carb-bd_dom.
    IPR012291. CBD_carb-bd_dom.
    IPR001919. Cellulose-bd_dom_fam2_bac.
    IPR008985. ConA-like_lec_gl_sf.
    IPR001137. Glyco_hydro_11.
    IPR013319. Glyco_hydro_11/12.
    IPR018208. Glyco_hydro_11_AS.
    [Graphical view]
    PfamiPF00457. Glyco_hydro_11. 1 hit.
    [Graphical view]
    PRINTSiPR00911. GLHYDRLASE11.
    SMARTiSM00637. CBD_II. 1 hit.
    [Graphical view]
    SUPFAMiSSF49384. SSF49384. 1 hit.
    SSF49899. SSF49899. 1 hit.
    PROSITEiPS51173. CBM2. 1 hit.
    PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
    PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P26515-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNLLVQPRRR RRGPVTLLVR SAWAVALAAL AALMLPGTAQ ADTVVTTNQE    50
    GTNNGYYYSF WTDSQGTVSM NMGSGGQYST SWRNTGNFVA GKGWANGGRR 100
    TVQYSGSFNP SGNAYLALYG WTSNPLVEYY IVDNWGTYRP TGEYKGTVTS 150
    DGGTYDIYKT TRVNKPSVEG TRTFDQYWSV RQSKRTGGTI TTGNHFDAWA 200
    RAGMPLGNFS YYMIMATEGY QSSGSSSINV GGTGGGDSGG GDNGGGGGGC 250
    TATVSAGQKW GDRYNLDVSV SGASDWTVTM NVPSPAKVLS NWNVNASYPS 300
    AQTLTARLNG SGNNWGATIQ ANANWTWPSV SCSAG 335
    Length:335
    Mass (Da):35,575
    Last modified:August 14, 2001 - v3
    Checksum:i513B1458BF8FF0CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64552 Genomic DNA. Translation: AAC06114.2.
    PIRiJS0590.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64552 Genomic DNA. Translation: AAC06114.2 .
    PIRi JS0590.

    3D structure databases

    ProteinModelPortali P26515.
    SMRi P26515. Positions 45-228.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi CBM2. Carbohydrate-Binding Module Family 2.
    GH11. Glycoside Hydrolase Family 11.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00114 .

    Family and domain databases

    Gene3Di 2.60.120.180. 1 hit.
    2.60.40.290. 1 hit.
    InterProi IPR008965. Carb-bd_dom.
    IPR012291. CBD_carb-bd_dom.
    IPR001919. Cellulose-bd_dom_fam2_bac.
    IPR008985. ConA-like_lec_gl_sf.
    IPR001137. Glyco_hydro_11.
    IPR013319. Glyco_hydro_11/12.
    IPR018208. Glyco_hydro_11_AS.
    [Graphical view ]
    Pfami PF00457. Glyco_hydro_11. 1 hit.
    [Graphical view ]
    PRINTSi PR00911. GLHYDRLASE11.
    SMARTi SM00637. CBD_II. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49384. SSF49384. 1 hit.
    SSF49899. SSF49899. 1 hit.
    PROSITEi PS51173. CBM2. 1 hit.
    PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
    PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequences of three genes specifying xylanases in Streptomyces lividans."
      Shareck F., Roy C., Yaguchi M., Morosoli R., Kluepfel D.
      Gene 107:75-82(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 42-72.
      Strain: 66 / 1326.
    2. "Analysis of DNA flanking the xlnB locus of Streptomyces lividans reveals genes encoding acetyl xylan esterase and the RNA component of ribonuclease P."
      Shareck F., Biely P., Morosoli R., Kluepfel D.
      Gene 153:105-109(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION TO 29-32 AND 252-307.
      Strain: 66 / 1326.
    3. Shareck F.
      Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: SEQUENCE REVISION TO 225.

    Entry informationi

    Entry nameiXYNB_STRLI
    AccessioniPrimary (citable) accession number: P26515
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1992
    Last sequence update: August 14, 2001
    Last modified: October 1, 2014
    This is version 82 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3