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Protein

Endo-1,4-beta-xylanase B

Gene

xlnB

Organism
Streptomyces lividans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Contributes to hydrolyze hemicellulose, the major component of plant cell-walls. XLNA and XLNB seem to act sequentially on the substrate to yield xylobiose and xylose as carbon sources.

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathwayi: xylan degradation

This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.
View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei128NucleophilePROSITE-ProRule annotation1
Active sitei218Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

UniPathwayiUPA00114

Protein family/group databases

CAZyiCBM2 Carbohydrate-Binding Module Family 2
GH11 Glycoside Hydrolase Family 11
mycoCLAPiXYN11B_STRLI

Names & Taxonomyi

Protein namesi
Recommended name:
Endo-1,4-beta-xylanase B (EC:3.2.1.8)
Short name:
Xylanase B
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase B
Gene namesi
Name:xlnB
OrganismiStreptomyces lividans
Taxonomic identifieri1916 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 411 PublicationAdd BLAST41
ChainiPRO_000000801042 – 335Endo-1,4-beta-xylanase BAdd BLAST294

Structurei

Secondary structure

1335
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi47 – 53Combined sources7
Beta strandi56 – 64Combined sources9
Beta strandi67 – 72Combined sources6
Beta strandi77 – 84Combined sources8
Beta strandi86 – 96Combined sources11
Beta strandi101 – 123Combined sources23
Turni124 – 126Combined sources3
Beta strandi127 – 137Combined sources11
Beta strandi143 – 150Combined sources8
Beta strandi153 – 165Combined sources13
Beta strandi170 – 183Combined sources14
Beta strandi187 – 191Combined sources5
Helixi192 – 201Combined sources10
Beta strandi213 – 231Combined sources19

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5EJ3X-ray1.31A/B1-234[»]
ProteinModelPortaliP26515
SMRiP26515
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 230GH11PROSITE-ProRule annotationAdd BLAST187
Domaini243 – 335CBM2PROSITE-ProRule annotationAdd BLAST93

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni231 – 249Linker ("hinge") (Gly-rich box)Add BLAST19

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.120.180, 1 hit
2.60.40.290, 1 hit
InterProiView protein in InterPro
IPR001919 CBD2
IPR008965 CBM2/CBM3_carb-bd_dom_sf
IPR012291 CBM2_carb-bd_dom_sf
IPR013320 ConA-like_dom_sf
IPR013319 GH11/12
IPR018208 GH11_AS_1
IPR033119 GH11_AS_2
IPR033123 GH11_dom
IPR001137 Glyco_hydro_11
PfamiView protein in Pfam
PF00457 Glyco_hydro_11, 1 hit
PRINTSiPR00911 GLHYDRLASE11
SMARTiView protein in SMART
SM00637 CBD_II, 1 hit
SUPFAMiSSF49384 SSF49384, 1 hit
SSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS51173 CBM2, 1 hit
PS00776 GH11_1, 1 hit
PS00777 GH11_2, 1 hit
PS51761 GH11_3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P26515-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLLVQPRRR RRGPVTLLVR SAWAVALAAL AALMLPGTAQ ADTVVTTNQE
60 70 80 90 100
GTNNGYYYSF WTDSQGTVSM NMGSGGQYST SWRNTGNFVA GKGWANGGRR
110 120 130 140 150
TVQYSGSFNP SGNAYLALYG WTSNPLVEYY IVDNWGTYRP TGEYKGTVTS
160 170 180 190 200
DGGTYDIYKT TRVNKPSVEG TRTFDQYWSV RQSKRTGGTI TTGNHFDAWA
210 220 230 240 250
RAGMPLGNFS YYMIMATEGY QSSGSSSINV GGTGGGDSGG GDNGGGGGGC
260 270 280 290 300
TATVSAGQKW GDRYNLDVSV SGASDWTVTM NVPSPAKVLS NWNVNASYPS
310 320 330
AQTLTARLNG SGNNWGATIQ ANANWTWPSV SCSAG
Length:335
Mass (Da):35,575
Last modified:August 14, 2001 - v3
Checksum:i513B1458BF8FF0CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64552 Genomic DNA Translation: AAC06114.2
PIRiJS0590

Similar proteinsi

Entry informationi

Entry nameiXYNB_STRLI
AccessioniPrimary (citable) accession number: P26515
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 14, 2001
Last modified: April 25, 2018
This is version 101 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing
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Main funding by: National Institutes of Health