Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P26488

- FIXK_AZOC5

UniProt

P26488 - FIXK_AZOC5

Protein

Nitrogen fixation regulation protein FixK

Gene

fixK

Organism
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 Aug 1992)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    FixK is a protein that regulates nitrogen fixation genes both positively and negatively. FixK is a positive regulator of NifA expression. FixK may bind DNA at the FNR consensus binding site.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi200 – 21920H-T-H motifPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. nitrogen fixation Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Nitrogen fixation, Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciACAU438753:GJF3-4718-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nitrogen fixation regulation protein FixK
    Gene namesi
    Name:fixK
    Ordered Locus Names:AZC_4653
    OrganismiAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)
    Taxonomic identifieri438753 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium
    ProteomesiUP000000270: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 248248Nitrogen fixation regulation protein FixKPRO_0000100156Add
    BLAST

    Expressioni

    Inductioni

    Oxygen is involved in the regulation of fixK expression. FixLJ strongly controls the transcription of fixK.

    Interactioni

    Protein-protein interaction databases

    STRINGi438753.AZC_4653.

    Structurei

    3D structure databases

    ProteinModelPortaliP26488.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini166 – 24176HTH crp-typePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 HTH crp-type DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0664.
    HOGENOMiHOG000186462.
    KOiK15861.
    OMAiHIRILNI.
    OrthoDBiEOG6Q5NX8.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    2.60.120.10. 1 hit.
    InterProiIPR018490. cNMP-bd-like.
    IPR000595. cNMP-bd_dom.
    IPR012318. HTH_CRP_2.
    IPR014710. RmlC-like_jellyroll.
    IPR001808. Tscrpt_reg_HTH_Crp.
    IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00027. cNMP_binding. 1 hit.
    PF00325. Crp. 1 hit.
    [Graphical view]
    PRINTSiPR00034. HTHCRP.
    SMARTiSM00100. cNMP. 1 hit.
    SM00419. HTH_CRP. 1 hit.
    [Graphical view]
    SUPFAMiSSF51206. SSF51206. 1 hit.
    PROSITEiPS00042. HTH_CRP_1. 1 hit.
    PS51063. HTH_CRP_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P26488-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSIAASVIAH IAPVPAQAYA HPMPSNRWSE MARGVAADES ARPAQVVAAL    50
    GTPAVFARNS EIFGDDQVAE NVYVVVSGVV RICKLMGDGR RQIEAFCLPG 100
    DAFGWETGER YRFSAEAVSE CRLVRVKRSV LFARAGSDPE LACALWALSF 150
    AELQRAQEHL LLLGRKTAQE RVGSFLLDLA RRSGTTNASH VTEVTLAMSR 200
    QDIADFLGLT IETVSRTLTY LEEQGTISLP SSRRVLLRDR SALRRLDS 248
    Length:248
    Mass (Da):27,104
    Last modified:August 1, 1992 - v1
    Checksum:i9106D34484F42C0C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X59071 Genomic DNA. Translation: CAA41794.1.
    AP009384 Genomic DNA. Translation: BAF90651.1.
    PIRiS16632.
    RefSeqiWP_012173172.1. NC_009937.1.
    YP_001527569.1. NC_009937.1.

    Genome annotation databases

    EnsemblBacteriaiBAF90651; BAF90651; AZC_4653.
    GeneIDi5689333.
    KEGGiazc:AZC_4653.
    PATRICi21026255. VBIAzoCau17976_4850.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X59071 Genomic DNA. Translation: CAA41794.1 .
    AP009384 Genomic DNA. Translation: BAF90651.1 .
    PIRi S16632.
    RefSeqi WP_012173172.1. NC_009937.1.
    YP_001527569.1. NC_009937.1.

    3D structure databases

    ProteinModelPortali P26488.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 438753.AZC_4653.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAF90651 ; BAF90651 ; AZC_4653 .
    GeneIDi 5689333.
    KEGGi azc:AZC_4653.
    PATRICi 21026255. VBIAzoCau17976_4850.

    Phylogenomic databases

    eggNOGi COG0664.
    HOGENOMi HOG000186462.
    KOi K15861.
    OMAi HIRILNI.
    OrthoDBi EOG6Q5NX8.

    Enzyme and pathway databases

    BioCyci ACAU438753:GJF3-4718-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    2.60.120.10. 1 hit.
    InterProi IPR018490. cNMP-bd-like.
    IPR000595. cNMP-bd_dom.
    IPR012318. HTH_CRP_2.
    IPR014710. RmlC-like_jellyroll.
    IPR001808. Tscrpt_reg_HTH_Crp.
    IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00027. cNMP_binding. 1 hit.
    PF00325. Crp. 1 hit.
    [Graphical view ]
    PRINTSi PR00034. HTHCRP.
    SMARTi SM00100. cNMP. 1 hit.
    SM00419. HTH_CRP. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51206. SSF51206. 1 hit.
    PROSITEi PS00042. HTH_CRP_1. 1 hit.
    PS51063. HTH_CRP_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Regulation of nitrogen fixation in Azorhizobium caulinodans: identification of a fixK-like gene, a positive regulator of nifA."
      Kaminski P.A., Mandon K., Arigoni F., Desnoues N., Elmerich C.
      Mol. Microbiol. 5:1983-1991(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
      Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
      Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43989 / DSM 5975 / ORS 571.

    Entry informationi

    Entry nameiFIXK_AZOC5
    AccessioniPrimary (citable) accession number: P26488
    Secondary accession number(s): A8I013
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1992
    Last sequence update: August 1, 1992
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3