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P26488 (FIXK_AZOC5) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nitrogen fixation regulation protein FixK
Gene names
Name:fixK
Ordered Locus Names:AZC_4653
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium

Protein attributes

Sequence length248 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

FixK is a protein that regulates nitrogen fixation genes both positively and negatively. FixK is a positive regulator of NifA expression. FixK may bind DNA at the FNR consensus binding site.

Induction

Oxygen is involved in the regulation of fixK expression. FixLJ strongly controls the transcription of fixK.

Sequence similarities

Contains 1 cyclic nucleotide-binding domain.

Contains 1 HTH crp-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 248248Nitrogen fixation regulation protein FixK
PRO_0000100156

Regions

Domain166 – 24176HTH crp-type
DNA binding200 – 21920H-T-H motif By similarity

Sequences

Sequence LengthMass (Da)Tools
P26488 [UniParc].

Last modified August 1, 1992. Version 1.
Checksum: 9106D34484F42C0C

FASTA24827,104
        10         20         30         40         50         60 
MSIAASVIAH IAPVPAQAYA HPMPSNRWSE MARGVAADES ARPAQVVAAL GTPAVFARNS 

        70         80         90        100        110        120 
EIFGDDQVAE NVYVVVSGVV RICKLMGDGR RQIEAFCLPG DAFGWETGER YRFSAEAVSE 

       130        140        150        160        170        180 
CRLVRVKRSV LFARAGSDPE LACALWALSF AELQRAQEHL LLLGRKTAQE RVGSFLLDLA 

       190        200        210        220        230        240 
RRSGTTNASH VTEVTLAMSR QDIADFLGLT IETVSRTLTY LEEQGTISLP SSRRVLLRDR 


SALRRLDS 

« Hide

References

« Hide 'large scale' references
[1]"Regulation of nitrogen fixation in Azorhizobium caulinodans: identification of a fixK-like gene, a positive regulator of nifA."
Kaminski P.A., Mandon K., Arigoni F., Desnoues N., Elmerich C.
Mol. Microbiol. 5:1983-1991(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43989 / DSM 5975 / ORS 571.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X59071 Genomic DNA. Translation: CAA41794.1.
AP009384 Genomic DNA. Translation: BAF90651.1.
PIRS16632.
RefSeqYP_001527569.1. NC_009937.1.

3D structure databases

ProteinModelPortalP26488.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING438753.AZC_4653.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAF90651; BAF90651; AZC_4653.
GeneID5689333.
KEGGazc:AZC_4653.
PATRIC21026255. VBIAzoCau17976_4850.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0664.
HOGENOMHOG000186462.
KOK15861.
OMAARTIDIM.
OrthoDBEOG6Q5NX8.
ProtClustDBCLSK979514.

Enzyme and pathway databases

BioCycACAU438753:GJF3-4718-MONOMER.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view]
PRINTSPR00034. HTHCRP.
SMARTSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMSSF51206. SSF51206. 1 hit.
PROSITEPS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFIXK_AZOC5
AccessionPrimary (citable) accession number: P26488
Secondary accession number(s): A8I013
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: February 19, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families