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P26470

- WAAK_SALTY

UniProt

P26470 - WAAK_SALTY

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Protein
Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
Gene
waaK, rfaK, STM3714
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS.

Catalytic activityi

UDP-N-acetyl-alpha-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-alpha-D-glucosaminyllipopolysaccharide.

Pathwayi

GO - Molecular functioni

  1. lipopolysaccharide N-acetylglucosaminyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. lipopolysaccharide core region biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciSENT99287:GCTI-3739-MONOMER.
UniPathwayiUPA00958.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipopolysaccharide 1,2-N-acetylglucosaminetransferase (EC:2.4.1.56)
Gene namesi
Name:waaK
Synonyms:rfaK
Ordered Locus Names:STM3714
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001014: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 381381Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
PRO_0000080306Add
BLAST

Proteomic databases

PaxDbiP26470.
PRIDEiP26470.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM3714.

Structurei

3D structure databases

ProteinModelPortaliP26470.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0438.
HOGENOMiHOG000028248.
KOiK03280.
OMAiSAIACIK.
OrthoDBiEOG6677RB.
PhylomeDBiP26470.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
[Graphical view]
PfamiPF00534. Glycos_transf_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P26470-1 [UniParc]FASTAAdd to Basket

« Hide

MIKKIIFTVT PIFSIPPRGA AAVETWIYQV AKRLSIPNAI ACIKNAGYPE    50
YNKINDNCDI HYIGFSKVYK RLFQKWTRLD PLPYSQRILN IRDKVTTQED 100
SVIVIHNSMK LYRQIRERNP NAKLVMHMHN AFEPELPDND AKIIVPSQFL 150
KAFYEERLPA AAVSIVPNGF CAETYKRNPQ DNLRQQLNIA EDATVLLYAG 200
RISPDKGILL LLQAFKQLRT LRSNIKLVVV GDPYASRKGE KAEYQKKVLD 250
AAKEIGTDCI MAGGQSPDQM HNFYHIADLV IVPSQVEEAF CMVAVEAMAA 300
GKAVLASKKG GISEFVLDGI TGYHLAEPMS SDSIINDINR ALADKERHQI 350
AEKAKSLVFS KYSWENVAQR FEEQMKNWFD K 381
Length:381
Mass (Da):43,152
Last modified:August 1, 1992 - v1
Checksum:iF60F37FF175372C6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M73826 Genomic DNA. Translation: AAA27207.1.
AE006468 Genomic DNA. Translation: AAL22573.1.
PIRiC41317.
RefSeqiNP_462614.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL22573; AAL22573; STM3714.
GeneIDi1255238.
KEGGistm:STM3714.
PATRICi32386263. VBISalEnt20916_3928.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M73826 Genomic DNA. Translation: AAA27207.1 .
AE006468 Genomic DNA. Translation: AAL22573.1 .
PIRi C41317.
RefSeqi NP_462614.1. NC_003197.1.

3D structure databases

ProteinModelPortali P26470.
ModBasei Search...

Protein-protein interaction databases

STRINGi 99287.STM3714.

Protein family/group databases

CAZyi GT4. Glycosyltransferase Family 4.

Proteomic databases

PaxDbi P26470.
PRIDEi P26470.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL22573 ; AAL22573 ; STM3714 .
GeneIDi 1255238.
KEGGi stm:STM3714.
PATRICi 32386263. VBISalEnt20916_3928.

Phylogenomic databases

eggNOGi COG0438.
HOGENOMi HOG000028248.
KOi K03280.
OMAi SAIACIK.
OrthoDBi EOG6677RB.
PhylomeDBi P26470.

Enzyme and pathway databases

UniPathwayi UPA00958 .
BioCyci SENT99287:GCTI-3739-MONOMER.

Family and domain databases

InterProi IPR001296. Glyco_trans_1.
[Graphical view ]
Pfami PF00534. Glycos_transf_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning, characterization, and DNA sequence of the rfaLK region for lipopolysaccharide synthesis in Salmonella typhimurium LT2."
    Maclachlan P.R., Kadam S.K., Sanderson K.E.
    J. Bacteriol. 173:7151-7163(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: LT2.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry nameiWAAK_SALTY
AccessioniPrimary (citable) accession number: P26470
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: July 9, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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