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Protein

Lipopolysaccharide 1,2-N-acetylglucosaminetransferase

Gene

waaK

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS.

Catalytic activityi

UDP-N-acetyl-alpha-D-glucosamine + [lipopolysaccharide] = UDP + N-acetyl-alpha-D-glucosaminyl-[lipopolysaccharide].

Pathwayi: LPS core biosynthesis

This protein is involved in the pathway LPS core biosynthesis, which is part of Bacterial outer membrane biogenesis.
View all proteins of this organism that are known to be involved in the pathway LPS core biosynthesis and in Bacterial outer membrane biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processLipopolysaccharide biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00958.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipopolysaccharide 1,2-N-acetylglucosaminetransferase (EC:2.4.1.56)
Gene namesi
Name:waaK
Synonyms:rfaK
Ordered Locus Names:STM3714
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000803061 – 381Lipopolysaccharide 1,2-N-acetylglucosaminetransferaseAdd BLAST381

Proteomic databases

PaxDbiP26470.
PRIDEiP26470.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM3714.

Structurei

3D structure databases

ProteinModelPortaliP26470.
SMRiP26470.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107XB0. Bacteria.
COG0438. LUCA.
HOGENOMiHOG000028248.
KOiK03280.
OMAiVHNEMFA.
PhylomeDBiP26470.

Family and domain databases

InterProiView protein in InterPro
IPR001296. Glyco_trans_1.
PfamiView protein in Pfam
PF00534. Glycos_transf_1. 1 hit.

Sequencei

Sequence statusi: Complete.

P26470-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKKIIFTVT PIFSIPPRGA AAVETWIYQV AKRLSIPNAI ACIKNAGYPE
60 70 80 90 100
YNKINDNCDI HYIGFSKVYK RLFQKWTRLD PLPYSQRILN IRDKVTTQED
110 120 130 140 150
SVIVIHNSMK LYRQIRERNP NAKLVMHMHN AFEPELPDND AKIIVPSQFL
160 170 180 190 200
KAFYEERLPA AAVSIVPNGF CAETYKRNPQ DNLRQQLNIA EDATVLLYAG
210 220 230 240 250
RISPDKGILL LLQAFKQLRT LRSNIKLVVV GDPYASRKGE KAEYQKKVLD
260 270 280 290 300
AAKEIGTDCI MAGGQSPDQM HNFYHIADLV IVPSQVEEAF CMVAVEAMAA
310 320 330 340 350
GKAVLASKKG GISEFVLDGI TGYHLAEPMS SDSIINDINR ALADKERHQI
360 370 380
AEKAKSLVFS KYSWENVAQR FEEQMKNWFD K
Length:381
Mass (Da):43,152
Last modified:August 1, 1992 - v1
Checksum:iF60F37FF175372C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M73826 Genomic DNA. Translation: AAA27207.1.
AE006468 Genomic DNA. Translation: AAL22573.1.
PIRiC41317.
RefSeqiNP_462614.1. NC_003197.2.
WP_000591818.1. NC_003197.2.

Genome annotation databases

EnsemblBacteriaiAAL22573; AAL22573; STM3714.
GeneIDi1255238.
KEGGistm:STM3714.
PATRICifig|99287.12.peg.3928.

Similar proteinsi

Entry informationi

Entry nameiWAAK_SALTY
AccessioniPrimary (citable) accession number: P26470
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: August 30, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families