Reviewed, UniProtKB/Swiss-Prot P26420 (SCRK_KLEPN)

Names and origin

Protein names

Recommended name:
    Fructokinase
    EC=2.7.1.4

Gene names

Name:

scrK

Organism

Klebsiella pneumoniae

Taxonomic identifier

573 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + D-fructose = ADP + D-fructose 6-phosphate.
Sequence similarities	Belongs to the carbohydrate kinase pfkB family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Gene Ontology (GO)
Biological process	D-ribose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW fructokinase activity Inferred from electronic annotation. Source: EC ribokinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 307	307	Fructokinase		PRO_0000080135

Sequences

	Sequence		Length	Mass (Da)
	P26420-1 [UniParc]. Last modified August 1, 1992. Version 1. Checksum: F8CB20B234B262FA	FASTA	307	32,344
	10 20 30 40 50 60 MNGKIWVLGD AVVDLLPDGE GRLLQCPGGA PANVAVGVAR LGGDSGFIGR VGDDPFGRFM 70 80 90 100 110 120 RHTLAQEQVD VNYMRLDAAQ RTSTVVVDLD SHGERTFTFM VRPSADLFLQ PEDLPPFAAG 130 140 150 160 170 180 QWLHVCSIAL SAEPSRSTTF AALEAIKRAG GYVSFDPNIR SDLWQDPQDL RDCLDRALAL 190 200 210 220 230 240 ADAIKLSEEE LAFISGSDDI VSGIARLNAR FQPTLLLVTQ GKAGVQAALR GQVSHFPARP 250 260 270 280 290 300 VVAVDTTGAG DAFVAGLLAG LAAHGIPDNL AALAPDLALA QTCGALATTA KGAMTALPYK DDLQRSL

References

[1]

"Molecular analysis of two fructokinases involved in sucrose metabolism of enteric bacteria." Aulkemeyer P., Ebner R., Heilenmann G., Jahreis K., Schmid K., Wrieden S., Lengeler J.W. Mol. Microbiol. 5:2913-2922(1991) [PubMed: 1809835] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 1033-5P14 / KAY2026.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X61004 Genomic DNA. Translation: CAA43322.1.
PIR	S18523.
3D structure databases
HSSP	HSSP built from PDB template 1LII based on UniProtKB Q9TVW2.
ModBase	Search...
Enzyme and pathway databases
BioCyc	MetaCyc:MON-12630.
BRENDA	2.7.1.4. 758.
Family and domain databases
InterPro	IPR011611. Carb/pur_kinase. IPR002173. Carboh/pur_kinase_PfkB_CS. IPR002139. Ribokinase. [Graphical view]
Pfam	PF00294. PfkB. 1 hit. [Graphical view]
PRINTS	PR00990. RIBOKINASE.
PROSITE	PS00583. PFKB_KINASES_1. 1 hit. PS00584. PFKB_KINASES_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SCRK_KLEPN

Accession

Primary (citable) accession number: P26420

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	August 1, 1992
Last modified:	June 16, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)