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P26343 (DAL80_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 115. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nitrogen regulatory protein DAL80
Alternative name(s):
Regulatory protein UGA43
Gene names
Name:DAL80
Synonyms:UGA43
Ordered Locus Names:YKR034W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Negative regulator of multiple nitrogen catabolic genes including the allantoin pathway genes.

Subcellular location

Nucleus.

Induction

Sensitive to nitrogen catabolite repression.

Sequence similarities

Contains 1 GATA-type zinc finger.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Nitrogen regulatory protein DAL80
PRO_0000083470

Regions

Zinc finger31 – 5525GATA-type
Compositional bias79 – 10022Asn-rich
Compositional bias101 – 1088Arg/Lys-rich (basic)

Experimental info

Sequence conflict61S → L in CAA42757. Ref.3
Sequence conflict2071V → I in CAA42757. Ref.3

Sequences

Sequence LengthMass (Da)Tools
P26343 [UniParc].

Last modified May 1, 1992. Version 1.
Checksum: F37BEB10038599EC

FASTA26930,166
        10         20         30         40         50         60 
MVLSDSLKLP SPTLSAAAGV DDCDGEDHPT CQNCFTVKTP LWRRDEHGTV LCNACGLFLK 

        70         80         90        100        110        120 
LHGEPRPISL KTDTIKSRNR KKLNNNNVNT NANTHSNDPN KIFKRKKRLL TTGGGSLPTN 

       130        140        150        160        170        180 
NPKVSILEKF MVSGSIKPLL KPKETVPNTK ECSTQRGKFS LDPCEPSGKN YLYQINGSDI 

       190        200        210        220        230        240 
YTSNIELTRL PNLSTLLEPS PFSDSAVPEI ELTWKLHNEE EVIKLKTKIS ELELVTDLYK 

       250        260 
KHIFQLNEKC KQLEVELHSR ASVQSHPQH 

« Hide

References

« Hide 'large scale' references
[1]"Expression of the DAL80 gene, whose product is homologous to the GATA factors and is a negative regulator of multiple nitrogen catabolic genes in Saccharomyces cerevisiae, is sensitive to nitrogen catabolite repression."
Cunningham T.S., Cooper T.G.
Mol. Cell. Biol. 11:6205-6215(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]Erratum
Cunningham T.S., Cooper T.G.
Mol. Cell. Biol. 12:2454-2454(1992) [PubMed] [Europe PMC] [Abstract]
[3]"The UGA43 negative regulatory gene of Saccharomyces cerevisiae contains both a GATA-1 type zinc finger and a putative leucine zipper."
Coornaert D., Vissers S., Andre B., Grenson M.
Curr. Genet. 21:301-307(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[4]"Complete DNA sequence of yeast chromosome XI."
Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. expand/collapse author list , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M77821 Genomic DNA. Translation: AAA34556.1.
X60199 Genomic DNA. Translation: CAA42757.1.
Z28259 Genomic DNA. Translation: CAA82107.1.
Z28258 Genomic DNA. Translation: CAA82106.1.
BK006944 Genomic DNA. Translation: DAA09187.1.
PIRS22781.
RefSeqNP_012959.1. NM_001179824.1.

3D structure databases

ProteinModelPortalP26343.
SMRP26343. Positions 30-70.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34165. 57 interactions.
DIPDIP-2094N.
IntActP26343. 19 interactions.
MINTMINT-483456.
STRING4932.YKR034W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYKR034W; YKR034W; YKR034W.
GeneID853904.
KEGGsce:YKR034W.

Organism-specific databases

CYGDYKR034w.
SGDS000001742. DAL80.

Phylogenomic databases

eggNOGCOG5641.
GeneTreeENSGT00750000117454.
KOK09184.
OMADVQCELP.
OrthoDBEOG7TQVCN.

Enzyme and pathway databases

BioCycYEAST:G3O-32007-MONOMER.

Gene expression databases

GenevestigatorP26343.

Family and domain databases

Gene3D3.30.50.10. 1 hit.
InterProIPR000679. Znf_GATA.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamPF00320. GATA. 1 hit.
[Graphical view]
PRINTSPR00619. GATAZNFINGER.
SMARTSM00401. ZnF_GATA. 1 hit.
[Graphical view]
PROSITEPS00344. GATA_ZN_FINGER_1. 1 hit.
PS50114. GATA_ZN_FINGER_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio975233.

Entry information

Entry nameDAL80_YEAST
AccessionPrimary (citable) accession number: P26343
Secondary accession number(s): D6VX97
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: June 11, 2014
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XI

Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families