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Protein

Nitrogen regulatory protein DAL80

Gene

DAL80

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Negative regulator of multiple nitrogen catabolic genes including the allantoin pathway genes.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri31 – 55GATA-typePROSITE-ProRule annotationAdd BLAST25

GO - Molecular functioni

GO - Biological processi

  • cell differentiation Source: GO_Central
  • negative regulation of transcription by RNA polymerase II Source: SGD
  • nitrate assimilation Source: UniProtKB-KW
  • nitrogen catabolite repression of transcription Source: SGD

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processNitrate assimilation, Transcription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-32007-MONOMER
ReactomeiR-SCE-5689880 Ub-specific processing proteases
R-SCE-9018519 Estrogen-dependent gene expression

Names & Taxonomyi

Protein namesi
Recommended name:
Nitrogen regulatory protein DAL80
Alternative name(s):
Regulatory protein UGA43
Gene namesi
Name:DAL80
Synonyms:UGA43
Ordered Locus Names:YKR034W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi

Organism-specific databases

EuPathDBiFungiDB:YKR034W
SGDiS000001742 DAL80

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000834701 – 269Nitrogen regulatory protein DAL80Add BLAST269

Proteomic databases

PaxDbiP26343
PRIDEiP26343

PTM databases

iPTMnetiP26343

Expressioni

Inductioni

Sensitive to nitrogen catabolite repression.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi34165, 89 interactors
DIPiDIP-2094N
IntActiP26343, 19 interactors
STRINGi4932.YKR034W

Structurei

3D structure databases

ProteinModelPortaliP26343
SMRiP26343
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi79 – 100Asn-richAdd BLAST22
Compositional biasi101 – 108Arg/Lys-rich (basic)8

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri31 – 55GATA-typePROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00760000119221
InParanoidiP26343
KOiK09184
OrthoDBiEOG092C43RR

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR000679 Znf_GATA
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00320 GATA, 1 hit
PRINTSiPR00619 GATAZNFINGER
SMARTiView protein in SMART
SM00401 ZnF_GATA, 1 hit
PROSITEiView protein in PROSITE
PS00344 GATA_ZN_FINGER_1, 1 hit
PS50114 GATA_ZN_FINGER_2, 1 hit

Sequencei

Sequence statusi: Complete.

P26343-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLSDSLKLP SPTLSAAAGV DDCDGEDHPT CQNCFTVKTP LWRRDEHGTV
60 70 80 90 100
LCNACGLFLK LHGEPRPISL KTDTIKSRNR KKLNNNNVNT NANTHSNDPN
110 120 130 140 150
KIFKRKKRLL TTGGGSLPTN NPKVSILEKF MVSGSIKPLL KPKETVPNTK
160 170 180 190 200
ECSTQRGKFS LDPCEPSGKN YLYQINGSDI YTSNIELTRL PNLSTLLEPS
210 220 230 240 250
PFSDSAVPEI ELTWKLHNEE EVIKLKTKIS ELELVTDLYK KHIFQLNEKC
260
KQLEVELHSR ASVQSHPQH
Length:269
Mass (Da):30,166
Last modified:May 1, 1992 - v1
Checksum:iF37BEB10038599EC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti6S → L in CAA42757 (PubMed:1525858).Curated1
Sequence conflicti207V → I in CAA42757 (PubMed:1525858).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M77821 Genomic DNA Translation: AAA34556.1
X60199 Genomic DNA Translation: CAA42757.1
Z28259 Genomic DNA Translation: CAA82107.1
Z28258 Genomic DNA Translation: CAA82106.1
BK006944 Genomic DNA Translation: DAA09187.1
PIRiS22781
RefSeqiNP_012959.1, NM_001179824.1

Genome annotation databases

EnsemblFungiiYKR034W; YKR034W; YKR034W
GeneIDi853904
KEGGisce:YKR034W

Similar proteinsi

Entry informationi

Entry nameiDAL80_YEAST
AccessioniPrimary (citable) accession number: P26343
Secondary accession number(s): D6VX97
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: May 23, 2018
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

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