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Protein

Cytochrome c oxidase polypeptide 6, mitochondrial

Gene

cxfA

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase polypeptide 6, mitochondrial (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide VI
Gene namesi
Name:cxfA
Synonyms:cox6
ORF Names:DDB_G0282097
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 3, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0282097 cxfA

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 53HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001940862 – 93Cytochrome c oxidase polypeptide 6, mitochondrialAdd BLAST92

Proteomic databases

PaxDbiP26310
PRIDEiP26310

Interactioni

Subunit structurei

Slime mold cytochrome c oxidase consists of at least seven different polypeptides species, subunits I, II, III, IV, V, VI, and VIIe/s in order of MW.

Protein-protein interaction databases

STRINGi44689.DDB0215013

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c oxidase IV family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiP26310
OMAiRYPKGFK

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P26310-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTGNESYNL RYPKGFKGYP YNMYKLEGYG TPKGYITLIG VVATLTVSGL
60 70 80 90
FFAKTRSNKR EYPTHNKEWR AKTLAYAKET NADPIYQLPK DKI
Length:93
Mass (Da):10,666
Last modified:January 23, 2007 - v2
Checksum:i6D73D3EA4A448A96
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X55672 mRNA Translation: CAA39207.1
AAFI02000045 Genomic DNA Translation: EAL66374.1
PIRiS17190 OGDO6
RefSeqiXP_640351.1, XM_635259.1

Genome annotation databases

EnsemblProtistsiEAL66374; EAL66374; DDB_G0282097
GeneIDi8623406
KEGGiddi:DDB_G0282097

Similar proteinsi

Entry informationi

Entry nameiCOX6_DICDI
AccessioniPrimary (citable) accession number: P26310
Secondary accession number(s): Q54T04
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 92 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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