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Reviewed, UniProtKB/Swiss-Prot P26236 (BCHM_RHOCA)

Last modified June 16, 2009. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Magnesium-protoporphyrin O-methyltransferase
    EC=2.1.1.11
Alternative name(s):
    Magnesium-protoporphyrin IX methyltransferase
Gene names
Name: bchM
OrganismRhodobacter capsulatus (Rhodopseudomonas capsulata)
Taxonomic identifier1061 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Converts Mg-protoporphyrin IX to Mg-protoporphyrin IX methylester using S-adenosyl-L-methionine as a cofactor.

Catalytic activity

S-adenosyl-L-methionine + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + magnesium protoporphyrin IX 13-methyl ester.

Pathway

Porphyrin biosynthesis; bacteriochlorophyll biosynthesis (light-independent).

Sequence similarities

Belongs to the methyltransferase superfamily.

Caution

Was originally (Ref.1) thought to be involved in formation of the cyclopentone ring of protochlorophyllide from Mg-protoporphyrin IX monomethyl ester.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 224224Magnesium-protoporphyrin O-methyltransferase
PRO_0000204420

Sequences

Sequence LengthMass (Da)Tools
P26236-1 [UniParc].

Last modified May 1, 1992. Version 1.
Checksum: B32BB9B3DD3CF9EC

FASTA22425,225
        10         20         30         40         50         60 
MPSDYAEIRN RVEHYFDRTA TRAWARLTTA DEKVSKVRQT VREGRDTMRA VMLSRLPDDL 

        70         80         90        100        110        120 
TGCRVMDAGC GTGLTTVELA RRGADVVAVD ISPQLIDIAK DRLPPELRGK VSFHVGDMAD 

       130        140        150        160        170        180 
PALGQFDYVV AMDSLIYYRA PDIGRVLTEL GKRTHSAIVF TVAPKTAFLM AFWWLGKLFP 

       190        200        210        220 
RSNRSPVMIP HALDKLQRHA GDSLIKIDRV ARGFYISECL EYRP 

« Hide

References

[1]"Nucleotide and deduced polypeptide sequences of the photosynthetic reaction-center, B870 antenna, and flanking polypeptides from R. capsulata."
Youvan D.C., Bylina E.J., Alberti M., Begusch H., Hearst J.E.
Cell 37:949-957(1984) [PubMed: 6744416] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Rhodobacter capsulatus genes involved in early steps of the bacteriochlorophyll biosynthetic pathway."
Yang Z.M., Bauer C.E.
J. Bacteriol. 172:5001-5010(1990) [PubMed: 2203738] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-19.
[3]"Heterologous expression of the bchM gene product from Rhodobacter capsulatus and demonstration that it encodes S-adenosyl-L-methionine:Mg-protoporphyrin IX methyltransferase."
Bollivar D.W., Jiang Z.Y., Bauer C.E., Beale S.I.
J. Bacteriol. 176:5290-5296(1994) [PubMed: 8071204] [Abstract]
Cited for: CHARACTERIZATION.

Cross-references

Sequence databases

Z11165 Genomic DNA. Translation: CAA77522.1.
K01183 Genomic DNA. No translation available.
M34843 Genomic DNA. No translation available.
PIRA28988.

3D structure databases

ModBaseSearch...

Enzyme and pathway databases

BRENDA2.1.1.11. 567.

Family and domain databases

InterProIPR010251. BchM_ChlM.
IPR010940. Mg_prot_MeTrfase_C.
[Graphical view]
PfamPF07109. Mg-por_mtran_C. 1 hit.
[Graphical view]
TIGRFAMsTIGR02021. BchM-ChlM. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBCHM_RHOCA
AccessionPrimary (citable) accession number: P26236
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: June 16, 2009
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents