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P26236 (BCHM_RHOCA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Magnesium-protoporphyrin O-methyltransferase

EC=2.1.1.11
Alternative name(s):
Magnesium-protoporphyrin IX methyltransferase
Gene names
Name:bchM
OrganismRhodobacter capsulatus (Rhodopseudomonas capsulata)
Taxonomic identifier1061 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Converts Mg-protoporphyrin IX to Mg-protoporphyrin IX methylester using S-adenosyl-L-methionine as a cofactor.

Catalytic activity

S-adenosyl-L-methionine + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + magnesium protoporphyrin IX 13-methyl ester.

Pathway

Porphyrin-containing compound metabolism; bacteriochlorophyll biosynthesis (light-independent).

Sequence similarities

Belongs to the class I-like SAM-binding methyltransferase superfamily. Magnesium protoporphyrin O-methyltransferase family.

Caution

Was originally (Ref.1) thought to be involved in formation of the cyclopentone ring of protochlorophyllide from Mg-protoporphyrin IX monomethyl ester.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 224224Magnesium-protoporphyrin O-methyltransferase
PRO_0000204420

Sequences

Sequence LengthMass (Da)Tools
P26236 [UniParc].

Last modified May 1, 1992. Version 1.
Checksum: B32BB9B3DD3CF9EC

FASTA22425,225
        10         20         30         40         50         60 
MPSDYAEIRN RVEHYFDRTA TRAWARLTTA DEKVSKVRQT VREGRDTMRA VMLSRLPDDL 

        70         80         90        100        110        120 
TGCRVMDAGC GTGLTTVELA RRGADVVAVD ISPQLIDIAK DRLPPELRGK VSFHVGDMAD 

       130        140        150        160        170        180 
PALGQFDYVV AMDSLIYYRA PDIGRVLTEL GKRTHSAIVF TVAPKTAFLM AFWWLGKLFP 

       190        200        210        220 
RSNRSPVMIP HALDKLQRHA GDSLIKIDRV ARGFYISECL EYRP 

« Hide

References

[1]"Nucleotide and deduced polypeptide sequences of the photosynthetic reaction-center, B870 antenna, and flanking polypeptides from R. capsulata."
Youvan D.C., Bylina E.J., Alberti M., Begusch H., Hearst J.E.
Cell 37:949-957(1984) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Rhodobacter capsulatus genes involved in early steps of the bacteriochlorophyll biosynthetic pathway."
Yang Z.M., Bauer C.E.
J. Bacteriol. 172:5001-5010(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-19.
[3]"Heterologous expression of the bchM gene product from Rhodobacter capsulatus and demonstration that it encodes S-adenosyl-L-methionine:Mg-protoporphyrin IX methyltransferase."
Bollivar D.W., Jiang Z.Y., Bauer C.E., Beale S.I.
J. Bacteriol. 176:5290-5296(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z11165 Genomic DNA. Translation: CAA77522.1.
K01183 Genomic DNA. No translation available.
M34843 Genomic DNA. No translation available.
PIRA28988.

3D structure databases

ProteinModelPortalP26236.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP26236. 1 interaction.
MINTMINT-7994775.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOGENOMHOG000154343.

Enzyme and pathway databases

UniPathwayUPA00671.

Family and domain databases

InterProIPR010251. Mg_prot_MeTrfase.
IPR010940. Mg_prot_MeTrfase_C.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamPF07109. Mg-por_mtran_C. 1 hit.
PF05175. MTS. 1 hit.
[Graphical view]
TIGRFAMsTIGR02021. BchM-ChlM. 1 hit.
PROSITEPS51556. SAM_MT_MG_PIX. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBCHM_RHOCA
AccessionPrimary (citable) accession number: P26236
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: November 13, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways