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P26236

- BCHM_RHOCA

UniProt

P26236 - BCHM_RHOCA

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Protein

Magnesium-protoporphyrin O-methyltransferase

Gene

bchM

Organism
Rhodobacter capsulatus (Rhodopseudomonas capsulata)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Converts Mg-protoporphyrin IX to Mg-protoporphyrin IX methylester using S-adenosyl-L-methionine as a cofactor.

Catalytic activityi

S-adenosyl-L-methionine + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + magnesium protoporphyrin IX 13-methyl ester.PROSITE-ProRule annotation

Pathwayi

GO - Molecular functioni

  1. magnesium protoporphyrin IX methyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. bacteriochlorophyll biosynthetic process Source: CACAO
  2. light-independent bacteriochlorophyll biosynthetic process Source: UniProtKB-UniPathway
  3. photosynthesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

Bacteriochlorophyll biosynthesis, Chlorophyll biosynthesis, Photosynthesis

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

UniPathwayiUPA00671.

Names & Taxonomyi

Protein namesi
Recommended name:
Magnesium-protoporphyrin O-methyltransferase (EC:2.1.1.11)
Alternative name(s):
Magnesium-protoporphyrin IX methyltransferase
Gene namesi
Name:bchM
OrganismiRhodobacter capsulatus (Rhodopseudomonas capsulata)
Taxonomic identifieri1061 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 224224Magnesium-protoporphyrin O-methyltransferasePRO_0000204420Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiP26236. 1 interaction.
MINTiMINT-7994775.

Structurei

3D structure databases

ProteinModelPortaliP26236.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. Magnesium protoporphyrin O-methyltransferase family.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000154343.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR010251. Mg_prot_MeTrfase.
IPR010940. Mg_prot_MeTrfase_C.
IPR029063. SAM-dependent_MTases-like.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF07109. Mg-por_mtran_C. 1 hit.
PF05175. MTS. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR02021. BchM-ChlM. 1 hit.
PROSITEiPS51556. SAM_MT_MG_PIX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P26236-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPSDYAEIRN RVEHYFDRTA TRAWARLTTA DEKVSKVRQT VREGRDTMRA
60 70 80 90 100
VMLSRLPDDL TGCRVMDAGC GTGLTTVELA RRGADVVAVD ISPQLIDIAK
110 120 130 140 150
DRLPPELRGK VSFHVGDMAD PALGQFDYVV AMDSLIYYRA PDIGRVLTEL
160 170 180 190 200
GKRTHSAIVF TVAPKTAFLM AFWWLGKLFP RSNRSPVMIP HALDKLQRHA
210 220
GDSLIKIDRV ARGFYISECL EYRP
Length:224
Mass (Da):25,225
Last modified:May 1, 1992 - v1
Checksum:iB32BB9B3DD3CF9EC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z11165 Genomic DNA. Translation: CAA77522.1.
K01183 Genomic DNA. No translation available.
M34843 Genomic DNA. No translation available.
PIRiA28988.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z11165 Genomic DNA. Translation: CAA77522.1 .
K01183 Genomic DNA. No translation available.
M34843 Genomic DNA. No translation available.
PIRi A28988.

3D structure databases

ProteinModelPortali P26236.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P26236. 1 interaction.
MINTi MINT-7994775.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOGENOMi HOG000154343.

Enzyme and pathway databases

UniPathwayi UPA00671 .

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
InterProi IPR010251. Mg_prot_MeTrfase.
IPR010940. Mg_prot_MeTrfase_C.
IPR029063. SAM-dependent_MTases-like.
IPR007848. Small_mtfrase_dom.
[Graphical view ]
Pfami PF07109. Mg-por_mtran_C. 1 hit.
PF05175. MTS. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR02021. BchM-ChlM. 1 hit.
PROSITEi PS51556. SAM_MT_MG_PIX. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide and deduced polypeptide sequences of the photosynthetic reaction-center, B870 antenna, and flanking polypeptides from R. capsulata."
    Youvan D.C., Bylina E.J., Alberti M., Begusch H., Hearst J.E.
    Cell 37:949-957(1984) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Rhodobacter capsulatus genes involved in early steps of the bacteriochlorophyll biosynthetic pathway."
    Yang Z.M., Bauer C.E.
    J. Bacteriol. 172:5001-5010(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-19.
  3. "Heterologous expression of the bchM gene product from Rhodobacter capsulatus and demonstration that it encodes S-adenosyl-L-methionine:Mg-protoporphyrin IX methyltransferase."
    Bollivar D.W., Jiang Z.Y., Bauer C.E., Beale S.I.
    J. Bacteriol. 176:5290-5296(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION.

Entry informationi

Entry nameiBCHM_RHOCA
AccessioniPrimary (citable) accession number: P26236
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: October 1, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Was originally thought to be involved in formation of the cyclopentone ring of protochlorophyllide from Mg-protoporphyrin IX monomethyl ester.1 Publication

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3