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Protein

Lipoprotein E

Gene

hel

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-8381.
BRENDAi3.1.3.2. 2529.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipoprotein E
Alternative name(s):
Outer membrane protein P4
Short name:
OMP P4
Gene namesi
Name:hel
Synonyms:ompP4
Ordered Locus Names:HI_0693
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Add
BLAST
Chaini21 – 274254Lipoprotein EPRO_0000018178Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi21 – 211N-palmitoyl cysteineCurated
Lipidationi21 – 211S-diacylglycerol cysteineCurated

Keywords - PTMi

Lipoprotein, Palmitate

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0693.

Structurei

Secondary structure

1
274
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi30 – 389Combined sources
Helixi41 – 499Combined sources
Helixi51 – 7020Combined sources
Beta strandi78 – 836Combined sources
Turni87 – 893Combined sources
Helixi93 – 10210Combined sources
Helixi108 – 1169Combined sources
Helixi126 – 13510Combined sources
Beta strandi138 – 14710Combined sources
Turni148 – 1514Combined sources
Helixi152 – 16211Combined sources
Helixi169 – 1713Combined sources
Beta strandi172 – 1776Combined sources
Helixi182 – 1909Combined sources
Beta strandi193 – 20210Combined sources
Helixi203 – 2064Combined sources
Turni209 – 2124Combined sources
Helixi215 – 22410Combined sources
Helixi225 – 2284Combined sources
Turni230 – 2323Combined sources
Beta strandi233 – 2353Combined sources
Beta strandi239 – 2424Combined sources
Helixi243 – 2464Combined sources
Helixi252 – 2543Combined sources
Helixi257 – 26711Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3OCUX-ray1.35A22-274[»]
3OCVX-ray1.55A22-274[»]
3OCWX-ray1.85A22-274[»]
3OCXX-ray1.90A22-274[»]
3OCYX-ray1.40A22-274[»]
3OCZX-ray1.35A22-274[»]
3SF0X-ray1.35A22-274[»]
ProteinModelPortaliP26093.
SMRiP26093. Positions 31-274.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP26093.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105CUR. Bacteria.
COG2503. LUCA.
OMAiLVKNCIK.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR005519. Acid_phosphat_B-like.
IPR023214. HAD-like_dom.
IPR006423. Lipo_e_P4.
[Graphical view]
PfamiPF03767. Acid_phosphat_B. 1 hit.
[Graphical view]
PIRSFiPIRSF019271. Acid_Ptase_C. 1 hit.
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01533. lipo_e_P4. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P26093-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTTLKMTAL AALSAFVLAG CGSHQMKSEG HANMQLQQQA VLGLNWMQDS
60 70 80 90 100
GEYKALAYQA YNAAKVAFDH AKVAKGKKKA VVADLDETML DNSPYAGWQV
110 120 130 140 150
QNNKPFDGKD WTRWVDARQS RAVPGAVEFN NYVNSHNGKV FYVTNRKDST
160 170 180 190 200
EKSGTIDDMK RLGFNGVEES AFYLKKDKSA KAARFAEIEK QGYEIVLYVG
210 220 230 240 250
DNLDDFGNTV YGKLNADRRA FVDQNQGKFG KTFIMLPNAN YGGWEGGLAE
260 270
GYFKKDTQGQ IKARLDAVQA WDGK
Length:274
Mass (Da):30,431
Last modified:November 1, 1995 - v2
Checksum:i047C693194155E6B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti30 – 301G → E in AAA51009 (PubMed:1715322).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M68502 Genomic DNA. Translation: AAA51009.1.
L42023 Genomic DNA. Translation: AAC22353.1.
PIRiB64087.
RefSeqiNP_438853.1. NC_000907.1.
WP_010869033.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22353; AAC22353; HI_0693.
GeneIDi949723.
KEGGihin:HI0693.
PATRICi20190007. VBIHaeInf48452_0725.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M68502 Genomic DNA. Translation: AAA51009.1.
L42023 Genomic DNA. Translation: AAC22353.1.
PIRiB64087.
RefSeqiNP_438853.1. NC_000907.1.
WP_010869033.1. NC_000907.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3OCUX-ray1.35A22-274[»]
3OCVX-ray1.55A22-274[»]
3OCWX-ray1.85A22-274[»]
3OCXX-ray1.90A22-274[»]
3OCYX-ray1.40A22-274[»]
3OCZX-ray1.35A22-274[»]
3SF0X-ray1.35A22-274[»]
ProteinModelPortaliP26093.
SMRiP26093. Positions 31-274.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0693.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22353; AAC22353; HI_0693.
GeneIDi949723.
KEGGihin:HI0693.
PATRICi20190007. VBIHaeInf48452_0725.

Phylogenomic databases

eggNOGiENOG4105CUR. Bacteria.
COG2503. LUCA.
OMAiLVKNCIK.

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-8381.
BRENDAi3.1.3.2. 2529.

Miscellaneous databases

EvolutionaryTraceiP26093.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR005519. Acid_phosphat_B-like.
IPR023214. HAD-like_dom.
IPR006423. Lipo_e_P4.
[Graphical view]
PfamiPF03767. Acid_phosphat_B. 1 hit.
[Graphical view]
PIRSFiPIRSF019271. Acid_Ptase_C. 1 hit.
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01533. lipo_e_P4. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHEL_HAEIN
AccessioniPrimary (citable) accession number: P26093
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: November 1, 1995
Last modified: September 7, 2016
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.