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Protein

Lipoprotein E

Gene

hel

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-8381.
BRENDAi3.1.3.2. 2529.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipoprotein E
Alternative name(s):
Outer membrane protein P4
Short name:
OMP P4
Gene namesi
Name:hel
Synonyms:ompP4
Ordered Locus Names:HI_0693
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Add BLAST20
ChainiPRO_000001817821 – 274Lipoprotein EAdd BLAST254

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi21N-palmitoyl cysteineCurated1
Lipidationi21S-diacylglycerol cysteineCurated1

Keywords - PTMi

Lipoprotein, Palmitate

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0693.

Structurei

Secondary structure

1274
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi30 – 38Combined sources9
Helixi41 – 49Combined sources9
Helixi51 – 70Combined sources20
Beta strandi78 – 83Combined sources6
Turni87 – 89Combined sources3
Helixi93 – 102Combined sources10
Helixi108 – 116Combined sources9
Helixi126 – 135Combined sources10
Beta strandi138 – 147Combined sources10
Turni148 – 151Combined sources4
Helixi152 – 162Combined sources11
Helixi169 – 171Combined sources3
Beta strandi172 – 177Combined sources6
Helixi182 – 190Combined sources9
Beta strandi193 – 202Combined sources10
Helixi203 – 206Combined sources4
Turni209 – 212Combined sources4
Helixi215 – 224Combined sources10
Helixi225 – 228Combined sources4
Turni230 – 232Combined sources3
Beta strandi233 – 235Combined sources3
Beta strandi239 – 242Combined sources4
Helixi243 – 246Combined sources4
Helixi252 – 254Combined sources3
Helixi257 – 267Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3OCUX-ray1.35A22-274[»]
3OCVX-ray1.55A22-274[»]
3OCWX-ray1.85A22-274[»]
3OCXX-ray1.90A22-274[»]
3OCYX-ray1.40A22-274[»]
3OCZX-ray1.35A22-274[»]
3SF0X-ray1.35A22-274[»]
ProteinModelPortaliP26093.
SMRiP26093.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP26093.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105CUR. Bacteria.
COG2503. LUCA.
OMAiLVKNCIK.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR005519. Acid_phosphat_B-like.
IPR023214. HAD-like_dom.
IPR006423. Lipo_e_P4.
[Graphical view]
PfamiPF03767. Acid_phosphat_B. 1 hit.
[Graphical view]
PIRSFiPIRSF019271. Acid_Ptase_C. 1 hit.
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01533. lipo_e_P4. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P26093-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTTLKMTAL AALSAFVLAG CGSHQMKSEG HANMQLQQQA VLGLNWMQDS
60 70 80 90 100
GEYKALAYQA YNAAKVAFDH AKVAKGKKKA VVADLDETML DNSPYAGWQV
110 120 130 140 150
QNNKPFDGKD WTRWVDARQS RAVPGAVEFN NYVNSHNGKV FYVTNRKDST
160 170 180 190 200
EKSGTIDDMK RLGFNGVEES AFYLKKDKSA KAARFAEIEK QGYEIVLYVG
210 220 230 240 250
DNLDDFGNTV YGKLNADRRA FVDQNQGKFG KTFIMLPNAN YGGWEGGLAE
260 270
GYFKKDTQGQ IKARLDAVQA WDGK
Length:274
Mass (Da):30,431
Last modified:November 1, 1995 - v2
Checksum:i047C693194155E6B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti30G → E in AAA51009 (PubMed:1715322).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M68502 Genomic DNA. Translation: AAA51009.1.
L42023 Genomic DNA. Translation: AAC22353.1.
PIRiB64087.
RefSeqiNP_438853.1. NC_000907.1.
WP_010869033.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22353; AAC22353; HI_0693.
GeneIDi949723.
KEGGihin:HI0693.
PATRICi20190007. VBIHaeInf48452_0725.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M68502 Genomic DNA. Translation: AAA51009.1.
L42023 Genomic DNA. Translation: AAC22353.1.
PIRiB64087.
RefSeqiNP_438853.1. NC_000907.1.
WP_010869033.1. NC_000907.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3OCUX-ray1.35A22-274[»]
3OCVX-ray1.55A22-274[»]
3OCWX-ray1.85A22-274[»]
3OCXX-ray1.90A22-274[»]
3OCYX-ray1.40A22-274[»]
3OCZX-ray1.35A22-274[»]
3SF0X-ray1.35A22-274[»]
ProteinModelPortaliP26093.
SMRiP26093.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0693.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22353; AAC22353; HI_0693.
GeneIDi949723.
KEGGihin:HI0693.
PATRICi20190007. VBIHaeInf48452_0725.

Phylogenomic databases

eggNOGiENOG4105CUR. Bacteria.
COG2503. LUCA.
OMAiLVKNCIK.

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-8381.
BRENDAi3.1.3.2. 2529.

Miscellaneous databases

EvolutionaryTraceiP26093.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR005519. Acid_phosphat_B-like.
IPR023214. HAD-like_dom.
IPR006423. Lipo_e_P4.
[Graphical view]
PfamiPF03767. Acid_phosphat_B. 1 hit.
[Graphical view]
PIRSFiPIRSF019271. Acid_Ptase_C. 1 hit.
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01533. lipo_e_P4. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHEL_HAEIN
AccessioniPrimary (citable) accession number: P26093
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.