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P26012

- ITB8_HUMAN

UniProt

P26012 - ITB8_HUMAN

Protein

Integrin beta-8

Gene

ITGB8

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 141 (01 Oct 2014)
      Sequence version 1 (01 May 1992)
      Previous versions | rss
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    Functioni

    Integrin alpha-V/beta-8 is a receptor for fibronectin.

    GO - Molecular functioni

    1. receptor activity Source: InterPro

    GO - Biological processi

    1. cell adhesion Source: ProtInc
    2. cell-matrix adhesion Source: InterPro
    3. extracellular matrix organization Source: Reactome
    4. ganglioside metabolic process Source: Ensembl
    5. integrin-mediated signaling pathway Source: UniProtKB-KW
    6. placenta blood vessel development Source: BHF-UCL

    Keywords - Molecular functioni

    Integrin, Receptor

    Keywords - Biological processi

    Cell adhesion

    Enzyme and pathway databases

    ReactomeiREACT_13552. Integrin cell surface interactions.
    REACT_150331. Molecules associated with elastic fibres.
    SignaLinkiP26012.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Integrin beta-8
    Gene namesi
    Name:ITGB8
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 7

    Organism-specific databases

    HGNCiHGNC:6163. ITGB8.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular vesicular exosome Source: UniProt
    2. integrin complex Source: ProtInc
    3. plasma membrane Source: Reactome

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA29962.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 4242Sequence AnalysisAdd
    BLAST
    Chaini43 – 769727Integrin beta-8PRO_0000016354Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi47 ↔ 469By similarity
    Disulfide bondi55 ↔ 65By similarity
    Disulfide bondi58 ↔ 94By similarity
    Disulfide bondi68 ↔ 83By similarity
    Disulfide bondi211 ↔ 218By similarity
    Glycosylationi233 – 2331N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi266 ↔ 307By similarity
    Glycosylationi402 – 4021N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi407 ↔ 419By similarity
    Glycosylationi421 – 4211N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi431 – 4311N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi456 – 4561N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi466 – 4661N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi467 ↔ 471By similarity
    Disulfide bondi494 ↔ 499By similarity
    Disulfide bondi526 ↔ 531By similarity
    Disulfide bondi528 ↔ 561By similarity
    Disulfide bondi533 ↔ 546By similarity
    Disulfide bondi567 ↔ 572By similarity
    Disulfide bondi574 ↔ 583By similarity
    Disulfide bondi585 ↔ 593By similarity
    Disulfide bondi607 ↔ 612By similarity
    Disulfide bondi609 ↔ 657By similarity
    Disulfide bondi614 ↔ 624By similarity
    Disulfide bondi627 ↔ 630By similarity
    Disulfide bondi634 ↔ 643By similarity
    Glycosylationi648 – 6481N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    MaxQBiP26012.
    PaxDbiP26012.
    PeptideAtlasiP26012.
    PRIDEiP26012.

    PTM databases

    PhosphoSiteiP26012.

    Expressioni

    Tissue specificityi

    Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells.

    Gene expression databases

    ArrayExpressiP26012.
    BgeeiP26012.
    CleanExiHS_ITGB8.
    GenevestigatoriP26012.

    Organism-specific databases

    HPAiHPA027796.
    HPA027797.

    Interactioni

    Subunit structurei

    Heterodimer of an alpha and a beta subunit. Beta-8 associates with alpha-V.

    Protein-protein interaction databases

    BioGridi109902. 1 interaction.
    IntActiP26012. 1 interaction.
    STRINGi9606.ENSP00000222573.

    Structurei

    3D structure databases

    ProteinModelPortaliP26012.
    SMRiP26012. Positions 45-683.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini43 – 684642ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini705 – 76965CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei685 – 70420HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini146 – 384239VWFAAdd
    BLAST
    Repeati471 – 51040IAdd
    BLAST
    Repeati511 – 55242IIAdd
    BLAST
    Repeati553 – 59240IIIAdd
    BLAST
    Repeati593 – 62937IVAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni471 – 629159Cysteine-rich tandem repeatsAdd
    BLAST

    Sequence similaritiesi

    Belongs to the integrin beta chain family.Curated
    Contains 1 VWFA domain.Curated

    Keywords - Domaini

    Repeat, Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG266569.
    HOGENOMiHOG000252936.
    HOVERGENiHBG006190.
    InParanoidiP26012.
    KOiK06591.
    OMAiIHPERIH.
    OrthoDBiEOG7T7GSB.
    PhylomeDBiP26012.
    TreeFamiTF105392.

    Family and domain databases

    Gene3Di3.40.50.410. 1 hit.
    InterProiIPR000742. EG-like_dom.
    IPR013032. EGF-like_CS.
    IPR013111. EGF_extracell.
    IPR015812. Integrin_bsu.
    IPR015442. Integrin_bsu-8.
    IPR002369. Integrin_bsu_N.
    IPR016201. Plexin-like_fold.
    IPR002035. VWF_A.
    [Graphical view]
    PANTHERiPTHR10082. PTHR10082. 1 hit.
    PTHR10082:SF9. PTHR10082:SF9. 1 hit.
    PfamiPF07974. EGF_2. 1 hit.
    PF00362. Integrin_beta. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002512. Integrin_B. 1 hit.
    PRINTSiPR01186. INTEGRINB.
    SMARTiSM00181. EGF. 1 hit.
    SM00187. INB. 1 hit.
    SM00423. PSI. 1 hit.
    SM00327. VWA. 1 hit.
    [Graphical view]
    SUPFAMiSSF103575. SSF103575. 1 hit.
    SSF53300. SSF53300. 1 hit.
    PROSITEiPS00022. EGF_1. 1 hit.
    PS01186. EGF_2. 1 hit.
    PS00243. INTEGRIN_BETA. 2 hits.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: P26012-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MCGSALAFFT AAFVCLQNDR RGPASFLWAA WVFSLVLGLG QGEDNRCASS    50
    NAASCARCLA LGPECGWCVQ EDFISGGSRS ERCDIVSNLI SKGCSVDSIE 100
    YPSVHVIIPT ENEINTQVTP GEVSIQLRPG AEANFMLKVH PLKKYPVDLY 150
    YLVDVSASMH NNIEKLNSVG NDLSRKMAFF SRDFRLGFGS YVDKTVSPYI 200
    SIHPERIHNQ CSDYNLDCMP PHGYIHVLSL TENITEFEKA VHRQKISGNI 250
    DTPEGGFDAM LQAAVCESHI GWRKEAKRLL LVMTDQTSHL ALDSKLAGIV 300
    VPNDGNCHLK NNVYVKSTTM EHPSLGQLSE KLIDNNINVI FAVQGKQFHW 350
    YKDLLPLLPG TIAGEIESKA ANLNNLVVEA YQKLISEVKV QVENQVQGIY 400
    FNITAICPDG SRKPGMEGCR NVTSNDEVLF NVTVTMKKCD VTGGKNYAII 450
    KPIGFNETAK IHIHRNCSCQ CEDNRGPKGK CVDETFLDSK CFQCDENKCH 500
    FDEDQFSSES CKSHKDQPVC SGRGVCVCGK CSCHKIKLGK VYGKYCEKDD 550
    FSCPYHHGNL CAGHGECEAG RCQCFSGWEG DRCQCPSAAA QHCVNSKGQV 600
    CSGRGTCVCG RCECTDPRSI GRFCEHCPTC YTACKENWNC MQCLHPHNLS 650
    QAILDQCKTS CALMEQQHYV DQTSECFSSP SYLRIFFIIF IVTFLIGLLK 700
    VLIIRQVILQ WNSNKIKSSS DYRVSASKKD KLILQSVCTR AVTYRREKPE 750
    EIKMDISKLN AHETFRCNF 769
    Length:769
    Mass (Da):85,632
    Last modified:May 1, 1992 - v1
    Checksum:iF7E3994F92B12A65
    GO
    Isoform 2 (identifier: P26012-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-135: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:634
    Mass (Da):71,284
    Checksum:i62E01B68236B2F76
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti552 – 5521S → F.
    Corresponds to variant rs5002476 [ dbSNP | Ensembl ].
    VAR_034028

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 135135Missing in isoform 2. 1 PublicationVSP_056531Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M73780 mRNA. Translation: AAA36034.1.
    AK295044 mRNA. Translation: BAG58095.1.
    AC004130 Genomic DNA. Translation: AAQ96845.1.
    CH236948 Genomic DNA. Translation: EAL24275.1.
    CH471073 Genomic DNA. Translation: EAW93725.1.
    CCDSiCCDS5370.1.
    PIRiA41029.
    RefSeqiNP_002205.1. NM_002214.2.
    XP_005249808.1. XM_005249751.2.
    UniGeneiHs.592171.

    Genome annotation databases

    EnsembliENST00000222573; ENSP00000222573; ENSG00000105855.
    ENST00000537992; ENSP00000441561; ENSG00000105855.
    GeneIDi3696.
    KEGGihsa:3696.
    UCSCiuc003suu.3. human.

    Polymorphism databases

    DMDMi124975.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M73780 mRNA. Translation: AAA36034.1 .
    AK295044 mRNA. Translation: BAG58095.1 .
    AC004130 Genomic DNA. Translation: AAQ96845.1 .
    CH236948 Genomic DNA. Translation: EAL24275.1 .
    CH471073 Genomic DNA. Translation: EAW93725.1 .
    CCDSi CCDS5370.1.
    PIRi A41029.
    RefSeqi NP_002205.1. NM_002214.2.
    XP_005249808.1. XM_005249751.2.
    UniGenei Hs.592171.

    3D structure databases

    ProteinModelPortali P26012.
    SMRi P26012. Positions 45-683.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 109902. 1 interaction.
    IntActi P26012. 1 interaction.
    STRINGi 9606.ENSP00000222573.

    PTM databases

    PhosphoSitei P26012.

    Polymorphism databases

    DMDMi 124975.

    Proteomic databases

    MaxQBi P26012.
    PaxDbi P26012.
    PeptideAtlasi P26012.
    PRIDEi P26012.

    Protocols and materials databases

    DNASUi 3696.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000222573 ; ENSP00000222573 ; ENSG00000105855 .
    ENST00000537992 ; ENSP00000441561 ; ENSG00000105855 .
    GeneIDi 3696.
    KEGGi hsa:3696.
    UCSCi uc003suu.3. human.

    Organism-specific databases

    CTDi 3696.
    GeneCardsi GC07P020370.
    HGNCi HGNC:6163. ITGB8.
    HPAi HPA027796.
    HPA027797.
    MIMi 604160. gene.
    neXtProti NX_P26012.
    PharmGKBi PA29962.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG266569.
    HOGENOMi HOG000252936.
    HOVERGENi HBG006190.
    InParanoidi P26012.
    KOi K06591.
    OMAi IHPERIH.
    OrthoDBi EOG7T7GSB.
    PhylomeDBi P26012.
    TreeFami TF105392.

    Enzyme and pathway databases

    Reactomei REACT_13552. Integrin cell surface interactions.
    REACT_150331. Molecules associated with elastic fibres.
    SignaLinki P26012.

    Miscellaneous databases

    ChiTaRSi ITGB8. human.
    GeneWikii ITGB8.
    GenomeRNAii 3696.
    NextBioi 14487.
    PROi P26012.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P26012.
    Bgeei P26012.
    CleanExi HS_ITGB8.
    Genevestigatori P26012.

    Family and domain databases

    Gene3Di 3.40.50.410. 1 hit.
    InterProi IPR000742. EG-like_dom.
    IPR013032. EGF-like_CS.
    IPR013111. EGF_extracell.
    IPR015812. Integrin_bsu.
    IPR015442. Integrin_bsu-8.
    IPR002369. Integrin_bsu_N.
    IPR016201. Plexin-like_fold.
    IPR002035. VWF_A.
    [Graphical view ]
    PANTHERi PTHR10082. PTHR10082. 1 hit.
    PTHR10082:SF9. PTHR10082:SF9. 1 hit.
    Pfami PF07974. EGF_2. 1 hit.
    PF00362. Integrin_beta. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002512. Integrin_B. 1 hit.
    PRINTSi PR01186. INTEGRINB.
    SMARTi SM00181. EGF. 1 hit.
    SM00187. INB. 1 hit.
    SM00423. PSI. 1 hit.
    SM00327. VWA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF103575. SSF103575. 1 hit.
    SSF53300. SSF53300. 1 hit.
    PROSITEi PS00022. EGF_1. 1 hit.
    PS01186. EGF_2. 1 hit.
    PS00243. INTEGRIN_BETA. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and expression of a divergent integrin subunit beta 8."
      Moyle M., Napier M.A., McLean J.W.
      J. Biol. Chem. 266:19650-19658(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Tissue: Placenta.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Brain.
    3. "The DNA sequence of human chromosome 7."
      Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
      , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
      Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "Human chromosome 7: DNA sequence and biology."
      Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., Kanematsu E., Gentles S.
      , Christopoulos C.C., Choufani S., Kwasnicka D., Zheng X.H., Lai Z., Nusskern D.R., Zhang Q., Gu Z., Lu F., Zeesman S., Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H.Q., Pelicci P.G., Lo-Coco F., Belloni E., Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A.P., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W., Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H., Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D., Tsui L.-C.
      Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiITB8_HUMAN
    AccessioniPrimary (citable) accession number: P26012
    Secondary accession number(s): A4D133, B4DHD4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1992
    Last sequence update: May 1, 1992
    Last modified: October 1, 2014
    This is version 141 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 7
      Human chromosome 7: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3