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Protein

Non-structural protein NS-S

Gene

NSS

Organism
Tomato spotted wilt virus (strain Bulgarian L3) (TSWV)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Forms filamentous inclusion bodies. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity).By similarity

Keywords - Molecular functioni

Suppressor of RNA silencing

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein NS-S
Gene namesi
Name:NSS
OrganismiTomato spotted wilt virus (strain Bulgarian L3) (TSWV)
Taxonomic identifieri36415 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA negative-strand virusesBunyaviridaeTospovirus
Virus hostiFrankliniella occidentalis (Western flower thrips) [TaxID: 133901]
Scirtothrips dorsalis [TaxID: 163899]
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081]
Thrips tabaci [TaxID: 161014]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 467467Non-structural protein NS-SPRO_0000221985Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the tospovirus NS-S protein family.Curated

Family and domain databases

InterProiIPR004915. NS-S_bunyaviral.
[Graphical view]
PfamiPF03231. Bunya_NS-S_2. 1 hit.
[Graphical view]
PIRSFiPIRSF003958. NS-S_TospoV. 1 hit.

Sequencei

Sequence statusi: Complete.

P26003-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSVYESII QTRASVWGST ASGKAVVDSY WIHELGTGSL LVQTQLYSDS
60 70 80 90 100
RSKSSFGYTA KVGNLPCEEE EILSQHVYIP IFDDIDFSIN IDDSVLALSV
110 120 130 140 150
CSNTVNTNGV KHQGHLKVLS PDQLHSIGST MNRSDIKDRF QLQEKDIIPN
160 170 180 190 200
DRYIEAANKG SLSCVKEHTY KIETCYNQAL GKVNVLSPNR NVHEWLYSFK
210 220 230 240 250
PSFNQVESNN RTVNSLAVKS LLMSAENNIM PNSQAFVKAS TDSHFKLSLW
260 270 280 290 300
LRVPKVLKQV SIQKLFKVAG DETNKTFYLS IVCIPNHNSV ETALNISVIC
310 320 330 340 350
KHQLPIRKCK APFELSMMFS DLKEPYNIVH DPSYPQRIVH ALLETHTSFA
360 370 380 390 400
QVLCNNLQED VIIYTLNNYE LTPGKLDLGE RTLNYSEDIC KRKYFLSKTL
410 420 430 440 450
ECLPSNTQTM SYLDSIQIPS WKIDFARGEI KISPQPVSVA KSLLKLDLSG
460
IKKKGSKISE THASGSK
Length:467
Mass (Da):52,414
Last modified:May 1, 1992 - v1
Checksum:i38E5CA4E802DB6DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13926 Genomic RNA. Translation: BAA03024.1.
PIRiJQ0954. MNVUW1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13926 Genomic RNA. Translation: BAA03024.1.
PIRiJQ0954. MNVUW1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR004915. NS-S_bunyaviral.
[Graphical view]
PfamiPF03231. Bunya_NS-S_2. 1 hit.
[Graphical view]
PIRSFiPIRSF003958. NS-S_TospoV. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Cloning and sequencing of the S RNA from a Bulgarian isolate of tomato spotted wilt virus."
    Maiss E., Ivanova L., Breyel E., Adam G.
    J. Gen. Virol. 72:461-464(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiNSS_TSWVL
AccessioniPrimary (citable) accession number: P26003
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: June 24, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.