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P26002

- NSS_TSWV1

UniProt

P26002 - NSS_TSWV1

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Protein

Non-structural protein NS-S

Gene
NSS
Organism
Tomato spotted wilt virus (strain Brazilian Br-01) (TSWV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms filamentous inclusion bodies. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.1 Publication

Keywords - Molecular functioni

Suppressor of RNA silencing

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein NS-S
Gene namesi
Name:NSS
OrganismiTomato spotted wilt virus (strain Brazilian Br-01) (TSWV)
Taxonomic identifieri36413 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaeTospovirus
Virus hostiFrankliniella occidentalis (Western flower thrips) [TaxID: 133901]
Scirtothrips dorsalis [TaxID: 163899]
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081]
Thrips tabaci [TaxID: 161014]
ProteomesiUP000006674: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 464464Non-structural protein NS-SPRO_0000221984Add
BLAST

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR004915. NS-S_bunyaviral.
[Graphical view]
PfamiPF03231. Bunya_NS-S_2. 1 hit.
[Graphical view]
PIRSFiPIRSF003958. NS-S_TospoV. 1 hit.

Sequencei

Sequence statusi: Complete.

P26002-1 [UniParc]FASTAAdd to Basket

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MSSSVYESII QTRASVWGST ASGKAVVDSY WIHELGTGSQ LVQTQLYSDS    50
RSKVVLWLYC KVGIFPVKKK RFLSQHVYIP IFDDIDFSIN IDNSVLALSV 100
CSNTVNANGV KHQGHLKVLS PAQLHSIESI MNRSDITDRF QLQEKDIIPN 150
DKYIEAANKG SLSCVKEHTY KIEMCYNQAL GKVNVLSPNR NVHEWLYSFK 200
PNFNQVESNN RTVNSLAVKS LLMSAENNIM PNSQASTDSH FKLSLWLRVP 250
KVLKQVSIQK LFKVAGDETN KTFYLSIACI PNHNSVETAL NITVICKHQL 300
PIRKCKAPFE LSMMFSDLKE PYNIVHDPSY PKGSVPMLWL ETHTSLHKFF 350
ATNLQEDVII YTLNNLELTP GKLDLGERTL NYSEDAYKRK YFLSKTLECL 400
PSNTQTMSYL DSIQIPSWKI DFARGEIKIS PQSISVAKSL LKLDLSGIKK 450
KESKVKEAYA SGSK 464
Length:464
Mass (Da):52,448
Last modified:May 1, 1992 - v1
Checksum:iAE5519179F9EF377
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D00645 Genomic RNA. Translation: BAA00540.1.
PIRiJQ0547. MNVUWC.
RefSeqiNP_049360.1. NC_002051.1.

Genome annotation databases

GeneIDi956580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D00645 Genomic RNA. Translation: BAA00540.1 .
PIRi JQ0547. MNVUWC.
RefSeqi NP_049360.1. NC_002051.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 956580.

Family and domain databases

InterProi IPR004915. NS-S_bunyaviral.
[Graphical view ]
Pfami PF03231. Bunya_NS-S_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF003958. NS-S_TospoV. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The S RNA segment of tomato spotted wilt virus has an ambisense character."
    de Haan P., Wagemakers L., Peters D., Goldbach R.
    J. Gen. Virol. 71:1001-1007(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. "Negative-strand tospoviruses and tenuiviruses carry a gene for a suppressor of gene silencing at analogous genomic positions."
    Bucher E., Sijen T., De Haan P., Goldbach R., Prins M.
    J. Virol. 77:1329-1336(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiNSS_TSWV1
AccessioniPrimary (citable) accession number: P26002
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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