Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P26002 (NSS_TSWV1) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length464 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms filamentous inclusion bodies. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Ref.2

Sequence similarities

Belongs to the tospovirus NS-S protein family.

Ontologies

Keywords
   Molecular functionSuppressor of RNA silencing
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 464464Non-structural protein NS-S
PRO_0000221984

Sequences

Sequence LengthMass (Da)Tools
P26002 [UniParc].

Last modified May 1, 1992. Version 1.
Checksum: AE5519179F9EF377

FASTA46452,448
        10         20         30         40         50         60 
MSSSVYESII QTRASVWGST ASGKAVVDSY WIHELGTGSQ LVQTQLYSDS RSKVVLWLYC 

        70         80         90        100        110        120 
KVGIFPVKKK RFLSQHVYIP IFDDIDFSIN IDNSVLALSV CSNTVNANGV KHQGHLKVLS 

       130        140        150        160        170        180 
PAQLHSIESI MNRSDITDRF QLQEKDIIPN DKYIEAANKG SLSCVKEHTY KIEMCYNQAL 

       190        200        210        220        230        240 
GKVNVLSPNR NVHEWLYSFK PNFNQVESNN RTVNSLAVKS LLMSAENNIM PNSQASTDSH 

       250        260        270        280        290        300 
FKLSLWLRVP KVLKQVSIQK LFKVAGDETN KTFYLSIACI PNHNSVETAL NITVICKHQL 

       310        320        330        340        350        360 
PIRKCKAPFE LSMMFSDLKE PYNIVHDPSY PKGSVPMLWL ETHTSLHKFF ATNLQEDVII 

       370        380        390        400        410        420 
YTLNNLELTP GKLDLGERTL NYSEDAYKRK YFLSKTLECL PSNTQTMSYL DSIQIPSWKI 

       430        440        450        460 
DFARGEIKIS PQSISVAKSL LKLDLSGIKK KESKVKEAYA SGSK 

« Hide

References

[1]"The S RNA segment of tomato spotted wilt virus has an ambisense character."
de Haan P., Wagemakers L., Peters D., Goldbach R.
J. Gen. Virol. 71:1001-1007(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"Negative-strand tospoviruses and tenuiviruses carry a gene for a suppressor of gene silencing at analogous genomic positions."
Bucher E., Sijen T., De Haan P., Goldbach R., Prins M.
J. Virol. 77:1329-1336(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D00645 Genomic RNA. Translation: BAA00540.1.
PIRMNVUWC. JQ0547.
RefSeqNP_049360.1. NC_002051.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID956580.

Family and domain databases

InterProIPR004915. NS-S_bunyaviral.
[Graphical view]
PfamPF03231. Bunya_NS-S_2. 1 hit.
[Graphical view]
PIRSFPIRSF003958. NS-S_TospoV. 1 hit.
ProtoNetSearch...

Entry information

Entry nameNSS_TSWV1
AccessionPrimary (citable) accession number: P26002
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families