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P26002

- NSS_TSWV1

UniProt

P26002 - NSS_TSWV1

Protein

Non-structural protein NS-S

Gene

NSS

Organism
Tomato spotted wilt virus (strain Brazilian Br-01) (TSWV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (01 May 1992)
      Previous versions | rss
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    Functioni

    Forms filamentous inclusion bodies. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.1 Publication

    Keywords - Molecular functioni

    Suppressor of RNA silencing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Non-structural protein NS-S
    Gene namesi
    Name:NSS
    OrganismiTomato spotted wilt virus (strain Brazilian Br-01) (TSWV)
    Taxonomic identifieri36413 [NCBI]
    Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaeTospovirus
    Virus hostiFrankliniella occidentalis (Western flower thrips) [TaxID: 133901]
    Scirtothrips dorsalis [TaxID: 163899]
    Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081]
    Thrips tabaci [TaxID: 161014]
    ProteomesiUP000006674: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 464464Non-structural protein NS-SPRO_0000221984Add
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the tospovirus NS-S protein family.Curated

    Family and domain databases

    InterProiIPR004915. NS-S_bunyaviral.
    [Graphical view]
    PfamiPF03231. Bunya_NS-S_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF003958. NS-S_TospoV. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P26002-1 [UniParc]FASTAAdd to Basket

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    MSSSVYESII QTRASVWGST ASGKAVVDSY WIHELGTGSQ LVQTQLYSDS    50
    RSKVVLWLYC KVGIFPVKKK RFLSQHVYIP IFDDIDFSIN IDNSVLALSV 100
    CSNTVNANGV KHQGHLKVLS PAQLHSIESI MNRSDITDRF QLQEKDIIPN 150
    DKYIEAANKG SLSCVKEHTY KIEMCYNQAL GKVNVLSPNR NVHEWLYSFK 200
    PNFNQVESNN RTVNSLAVKS LLMSAENNIM PNSQASTDSH FKLSLWLRVP 250
    KVLKQVSIQK LFKVAGDETN KTFYLSIACI PNHNSVETAL NITVICKHQL 300
    PIRKCKAPFE LSMMFSDLKE PYNIVHDPSY PKGSVPMLWL ETHTSLHKFF 350
    ATNLQEDVII YTLNNLELTP GKLDLGERTL NYSEDAYKRK YFLSKTLECL 400
    PSNTQTMSYL DSIQIPSWKI DFARGEIKIS PQSISVAKSL LKLDLSGIKK 450
    KESKVKEAYA SGSK 464
    Length:464
    Mass (Da):52,448
    Last modified:May 1, 1992 - v1
    Checksum:iAE5519179F9EF377
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D00645 Genomic RNA. Translation: BAA00540.1.
    PIRiJQ0547. MNVUWC.
    RefSeqiNP_049360.1. NC_002051.1.

    Genome annotation databases

    GeneIDi956580.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D00645 Genomic RNA. Translation: BAA00540.1 .
    PIRi JQ0547. MNVUWC.
    RefSeqi NP_049360.1. NC_002051.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 956580.

    Family and domain databases

    InterProi IPR004915. NS-S_bunyaviral.
    [Graphical view ]
    Pfami PF03231. Bunya_NS-S_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF003958. NS-S_TospoV. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The S RNA segment of tomato spotted wilt virus has an ambisense character."
      de Haan P., Wagemakers L., Peters D., Goldbach R.
      J. Gen. Virol. 71:1001-1007(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    2. "Negative-strand tospoviruses and tenuiviruses carry a gene for a suppressor of gene silencing at analogous genomic positions."
      Bucher E., Sijen T., De Haan P., Goldbach R., Prins M.
      J. Virol. 77:1329-1336(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.

    Entry informationi

    Entry nameiNSS_TSWV1
    AccessioniPrimary (citable) accession number: P26002
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1992
    Last sequence update: May 1, 1992
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3