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P25795

- AL7A1_PEA

UniProt

P25795 - AL7A1_PEA

Protein

Aldehyde dehydrogenase family 7 member A1

Gene
N/A
Organism
Pisum sativum (Garden pea)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    An aldehyde + NAD+ + H2O = a carboxylate + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei165 – 1651Transition state stabilizerBy similarity
    Active sitei266 – 2661Proton acceptorPROSITE-ProRule annotation
    Active sitei300 – 3001NucleophilePROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi244 – 2496NADBy similarity

    GO - Molecular functioni

    1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC

    GO - Biological processi

    1. response to stress Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Stress response

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciRETL1328306-WGS:GSTH-4148-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aldehyde dehydrogenase family 7 member A1 (EC:1.2.1.3)
    Alternative name(s):
    Antiquitin-1
    Turgor-responsive protein 26G
    OrganismiPisum sativum (Garden pea)
    Taxonomic identifieri3888 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 508507Aldehyde dehydrogenase family 7 member A1PRO_0000056498Add
    BLAST

    Proteomic databases

    PRIDEiP25795.

    Expressioni

    Inductioni

    By dehydration of shoots but not roots and not by heat shock or ABA.

    Interactioni

    Subunit structurei

    Homotetramer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP25795.
    SMRiP25795. Positions 10-507.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P25795-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGSDSNNLGF LKEIGLGATN IGSFINGQWK ANGPTVHSVN PSTNQVIASV    50
    TEATLDDYEE GLRASSEAAK TWRTVPAPKR GEIVRQIGDA LRAKLDPLGR 100
    LVALEMGKIL AEGIGEVQEI IDMCDYSVGL SRQLNGSIIP SERPEHMMFE 150
    VWNPLGIVGV ITAFNFPCAV LGWNACIALV GGNTVVWKGA PTTPLITVAV 200
    TKLIAEVFER NNLPGAIFTA LCGGADIGHA IAKDTRIPLV SFTGSSKVGA 250
    LVQQTVSQRF GKTLLELSGN NAIIVMDDAD ITLAVRSIFF AAVGTAGQRC 300
    TTCRRLYLHE SVYANVLEQL TALYKQVKIG NPLEEGTLVG PLHTRSAVEN 350
    FKNGISAIKS QGGKIVTGGS VLESEGNFVV PTIVEISADA AVVKEELFAP 400
    VLYVMKFKDL EEAIALNNSV PQGLSSSIFT QKPSTIFKWI GPSGSDCGIV 450
    NVNIPTNGAE IGGAFGGEKA TGGGREAGSD SWKQYMRRST CTINYGSELP 500
    LAQGINFG 508
    Length:508
    Mass (Da):53,789
    Last modified:January 23, 2007 - v3
    Checksum:iCC88F367B52E923D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X54359 mRNA. Translation: CAA38243.1.
    PIRiS11863.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X54359 mRNA. Translation: CAA38243.1 .
    PIRi S11863.

    3D structure databases

    ProteinModelPortali P25795.
    SMRi P25795. Positions 10-507.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P25795.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    BioCyci RETL1328306-WGS:GSTH-4148-MONOMER.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Turgor-responsive gene transcription and RNA levels increase rapidly when pea shoots are wilted. Sequence and expression of three inducible genes."
      Guerrero F.D., Jones J.T., Mullet J.E.
      Plant Mol. Biol. 15:11-26(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Progress No. 9.
    2. "First purification of the antiquitin protein and demonstration of its enzymatic activity."
      Tang W.-K., Cheng C.H.K., Fong W.-P.
      FEBS Lett. 516:183-186(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 2-16.

    Entry informationi

    Entry nameiAL7A1_PEA
    AccessioniPrimary (citable) accession number: P25795
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1992
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 77 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3