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P25795

- AL7A1_PEA

UniProt

P25795 - AL7A1_PEA

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Protein

Aldehyde dehydrogenase family 7 member A1

Gene
N/A
Organism
Pisum sativum (Garden pea)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei165 – 1651Transition state stabilizerBy similarity
Active sitei266 – 2661Proton acceptorPROSITE-ProRule annotation
Active sitei300 – 3001NucleophilePROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi244 – 2496NADBy similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC

GO - Biological processi

  1. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Stress response

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-4148-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldehyde dehydrogenase family 7 member A1 (EC:1.2.1.3)
Alternative name(s):
Antiquitin-1
Turgor-responsive protein 26G
OrganismiPisum sativum (Garden pea)
Taxonomic identifieri3888 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 508507Aldehyde dehydrogenase family 7 member A1PRO_0000056498Add
BLAST

Proteomic databases

PRIDEiP25795.

Expressioni

Inductioni

By dehydration of shoots but not roots and not by heat shock or ABA.

Interactioni

Subunit structurei

Homotetramer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP25795.
SMRiP25795. Positions 10-507.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P25795-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGSDSNNLGF LKEIGLGATN IGSFINGQWK ANGPTVHSVN PSTNQVIASV
60 70 80 90 100
TEATLDDYEE GLRASSEAAK TWRTVPAPKR GEIVRQIGDA LRAKLDPLGR
110 120 130 140 150
LVALEMGKIL AEGIGEVQEI IDMCDYSVGL SRQLNGSIIP SERPEHMMFE
160 170 180 190 200
VWNPLGIVGV ITAFNFPCAV LGWNACIALV GGNTVVWKGA PTTPLITVAV
210 220 230 240 250
TKLIAEVFER NNLPGAIFTA LCGGADIGHA IAKDTRIPLV SFTGSSKVGA
260 270 280 290 300
LVQQTVSQRF GKTLLELSGN NAIIVMDDAD ITLAVRSIFF AAVGTAGQRC
310 320 330 340 350
TTCRRLYLHE SVYANVLEQL TALYKQVKIG NPLEEGTLVG PLHTRSAVEN
360 370 380 390 400
FKNGISAIKS QGGKIVTGGS VLESEGNFVV PTIVEISADA AVVKEELFAP
410 420 430 440 450
VLYVMKFKDL EEAIALNNSV PQGLSSSIFT QKPSTIFKWI GPSGSDCGIV
460 470 480 490 500
NVNIPTNGAE IGGAFGGEKA TGGGREAGSD SWKQYMRRST CTINYGSELP

LAQGINFG
Length:508
Mass (Da):53,789
Last modified:January 23, 2007 - v3
Checksum:iCC88F367B52E923D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54359 mRNA. Translation: CAA38243.1.
PIRiS11863.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54359 mRNA. Translation: CAA38243.1 .
PIRi S11863.

3D structure databases

ProteinModelPortali P25795.
SMRi P25795. Positions 10-507.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P25795.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

BioCyci RETL1328306-WGS:GSTH-4148-MONOMER.

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
PROSITEi PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Turgor-responsive gene transcription and RNA levels increase rapidly when pea shoots are wilted. Sequence and expression of three inducible genes."
    Guerrero F.D., Jones J.T., Mullet J.E.
    Plant Mol. Biol. 15:11-26(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Progress No. 9.
  2. "First purification of the antiquitin protein and demonstration of its enzymatic activity."
    Tang W.-K., Cheng C.H.K., Fong W.-P.
    FEBS Lett. 516:183-186(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-16.

Entry informationi

Entry nameiAL7A1_PEA
AccessioniPrimary (citable) accession number: P25795
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: January 23, 2007
Last modified: October 1, 2014
This is version 77 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3