Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P25750

- CH60_BUCAI

UniProt

P25750 - CH60_BUCAI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

60 kDa chaperonin

Gene

groL

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. protein refolding Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-19-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Symbionin
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation, mopA, symL
Ordered Locus Names:BU019
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 54854860 kDa chaperoninPRO_0000063305Add
BLAST

Proteomic databases

PRIDEiP25750.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi107806.BU019.

Structurei

3D structure databases

ProteinModelPortaliP25750.
SMRiP25750. Positions 2-526.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0459.
HOGENOMiHOG000076290.
KOiK04077.
OMAiVLFGNDA.
OrthoDBiEOG6JDWBZ.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60.
InterProiIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P25750-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAAKDVKFGN EARIKMLRGV NVLADAVKVT LGPKGRNVVL DKSFGAPSIT
60 70 80 90 100
KDGVSVAREI ELEDKFENMG AQMVKEVASK ANDAAGDGTT TATLLAQSIV
110 120 130 140 150
NEGLKAVAAG MNPMDLKRGI DKAVISAVEE LKHLSVPCSD SKAITQVGTI
160 170 180 190 200
SANADEKVGS LIAEAMEKVG NDGVITVEEG TGLQDELEVV KGMQFDRGYL
210 220 230 240 250
SPYFINKPET GIVELENPYI LMADKKISNV REMLPILESV AKSGKPLLII
260 270 280 290 300
SEDLEGEALA TLVVNSMRGI VKVAAVKAPG FGDRRKAMLQ DISILTGGSV
310 320 330 340 350
ISEELAMELE KSTLEDLGQA KRVVISKDTT TIIGGVGEKH SIQSRISQIR
360 370 380 390 400
QEIQEATSDY DKEKLNERLA KLSGGVAVLK VGAATEVEMK EKKARVEDAL
410 420 430 440 450
HATRAAVEEG VVAGGGVALV RVAGKIADLR GQNEDQNVGI RVALRAMEAP
460 470 480 490 500
LRQIVSNSGE EPSVVTNNVK DGKGNYGYNA ATDEYGDMID FGILDPTKVT
510 520 530 540
RSALQYAASV AGLMITTECM VTDLPKEDKS SDSSSSPAGG MGGMGGMM
Length:548
Mass (Da):57,911
Last modified:May 1, 1992 - v1
Checksum:i9B33AE1E629E7592
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X61150 Genomic DNA. Translation: CAA43460.1.
BA000003 Genomic DNA. Translation: BAB12746.1.
RefSeqiNP_239860.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB12746; BAB12746; BAB12746.
GeneIDi1109527.
KEGGibuc:BU019.
PATRICi21243542. VBIBucAph127364_0031.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X61150 Genomic DNA. Translation: CAA43460.1 .
BA000003 Genomic DNA. Translation: BAB12746.1 .
RefSeqi NP_239860.1. NC_002528.1.

3D structure databases

ProteinModelPortali P25750.
SMRi P25750. Positions 2-526.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 107806.BU019.

Proteomic databases

PRIDEi P25750.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB12746 ; BAB12746 ; BAB12746 .
GeneIDi 1109527.
KEGGi buc:BU019.
PATRICi 21243542. VBIBucAph127364_0031.

Phylogenomic databases

eggNOGi COG0459.
HOGENOMi HOG000076290.
KOi K04077.
OMAi VLFGNDA.
OrthoDBi EOG6JDWBZ.

Enzyme and pathway databases

BioCyci BAPH107806:GBZJ-19-MONOMER.

Family and domain databases

Gene3Di 1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPi MF_00600. CH60.
InterProi IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view ]
PANTHERi PTHR11353. PTHR11353. 1 hit.
Pfami PF00118. Cpn60_TCP1. 1 hit.
[Graphical view ]
PRINTSi PR00298. CHAPERONIN60.
SUPFAMi SSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsi TIGR02348. GroEL. 1 hit.
PROSITEi PS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structures of chaperonins from an intracellular symbiont and their functional expression in Escherichia coli groE mutants."
    Ohtaka C., Nakamura H., Ishikawa H.
    J. Bacteriol. 174:1869-1874(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiCH60_BUCAI
AccessioniPrimary (citable) accession number: P25750
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: October 29, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3