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P25750

- CH60_BUCAI

UniProt

P25750 - CH60_BUCAI

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Protein
60 kDa chaperonin
Gene
groL, groEL, mopA, symL, BU019
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions By similarity.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. protein refolding Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-19-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin
Alternative name(s):
GroEL protein
Protein Cpn60
Symbionin
Gene namesi
Name:groL
Synonyms:groEL, mopA, symL
Ordered Locus Names:BU019
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 54854860 kDa chaperoninUniRule annotation
PRO_0000063305Add
BLAST

Proteomic databases

PRIDEiP25750.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits By similarity.

Protein-protein interaction databases

STRINGi107806.BU019.

Structurei

3D structure databases

ProteinModelPortaliP25750.
SMRiP25750. Positions 2-526.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0459.
HOGENOMiHOG000076290.
KOiK04077.
OMAiVLFGNDA.
OrthoDBiEOG6JDWBZ.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60.
InterProiIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P25750-1 [UniParc]FASTAAdd to Basket

« Hide

MAAKDVKFGN EARIKMLRGV NVLADAVKVT LGPKGRNVVL DKSFGAPSIT    50
KDGVSVAREI ELEDKFENMG AQMVKEVASK ANDAAGDGTT TATLLAQSIV 100
NEGLKAVAAG MNPMDLKRGI DKAVISAVEE LKHLSVPCSD SKAITQVGTI 150
SANADEKVGS LIAEAMEKVG NDGVITVEEG TGLQDELEVV KGMQFDRGYL 200
SPYFINKPET GIVELENPYI LMADKKISNV REMLPILESV AKSGKPLLII 250
SEDLEGEALA TLVVNSMRGI VKVAAVKAPG FGDRRKAMLQ DISILTGGSV 300
ISEELAMELE KSTLEDLGQA KRVVISKDTT TIIGGVGEKH SIQSRISQIR 350
QEIQEATSDY DKEKLNERLA KLSGGVAVLK VGAATEVEMK EKKARVEDAL 400
HATRAAVEEG VVAGGGVALV RVAGKIADLR GQNEDQNVGI RVALRAMEAP 450
LRQIVSNSGE EPSVVTNNVK DGKGNYGYNA ATDEYGDMID FGILDPTKVT 500
RSALQYAASV AGLMITTECM VTDLPKEDKS SDSSSSPAGG MGGMGGMM 548
Length:548
Mass (Da):57,911
Last modified:May 1, 1992 - v1
Checksum:i9B33AE1E629E7592
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X61150 Genomic DNA. Translation: CAA43460.1.
BA000003 Genomic DNA. Translation: BAB12746.1.
RefSeqiNP_239860.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB12746; BAB12746; BAB12746.
GeneIDi1109527.
KEGGibuc:BU019.
PATRICi21243542. VBIBucAph127364_0031.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X61150 Genomic DNA. Translation: CAA43460.1 .
BA000003 Genomic DNA. Translation: BAB12746.1 .
RefSeqi NP_239860.1. NC_002528.1.

3D structure databases

ProteinModelPortali P25750.
SMRi P25750. Positions 2-526.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 107806.BU019.

Proteomic databases

PRIDEi P25750.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB12746 ; BAB12746 ; BAB12746 .
GeneIDi 1109527.
KEGGi buc:BU019.
PATRICi 21243542. VBIBucAph127364_0031.

Phylogenomic databases

eggNOGi COG0459.
HOGENOMi HOG000076290.
KOi K04077.
OMAi VLFGNDA.
OrthoDBi EOG6JDWBZ.

Enzyme and pathway databases

BioCyci BAPH107806:GBZJ-19-MONOMER.

Family and domain databases

Gene3Di 1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPi MF_00600. CH60.
InterProi IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view ]
PANTHERi PTHR11353. PTHR11353. 1 hit.
Pfami PF00118. Cpn60_TCP1. 1 hit.
[Graphical view ]
PRINTSi PR00298. CHAPERONIN60.
SUPFAMi SSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsi TIGR02348. GroEL. 1 hit.
PROSITEi PS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structures of chaperonins from an intracellular symbiont and their functional expression in Escherichia coli groE mutants."
    Ohtaka C., Nakamura H., Ishikawa H.
    J. Bacteriol. 174:1869-1874(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiCH60_BUCAI
AccessioniPrimary (citable) accession number: P25750
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: May 14, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi