Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P25750

- CH60_BUCAI

UniProt

P25750 - CH60_BUCAI

Protein

60 kDa chaperonin

Gene

groL

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 97 (01 Oct 2014)
      Sequence version 1 (01 May 1992)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. protein refolding Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Chaperone

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBAPH107806:GBZJ-19-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    60 kDa chaperoninUniRule annotation
    Alternative name(s):
    GroEL proteinUniRule annotation
    Protein Cpn60UniRule annotation
    Symbionin
    Gene namesi
    Name:groLUniRule annotation
    Synonyms:groELUniRule annotation, mopA, symL
    Ordered Locus Names:BU019
    OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
    Taxonomic identifieri107806 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000001806: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 54854860 kDa chaperoninPRO_0000063305Add
    BLAST

    Proteomic databases

    PRIDEiP25750.

    Interactioni

    Subunit structurei

    Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi107806.BU019.

    Structurei

    3D structure databases

    ProteinModelPortaliP25750.
    SMRiP25750. Positions 2-526.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the chaperonin (HSP60) family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0459.
    HOGENOMiHOG000076290.
    KOiK04077.
    OMAiVLFGNDA.
    OrthoDBiEOG6JDWBZ.

    Family and domain databases

    Gene3Di1.10.560.10. 2 hits.
    3.50.7.10. 1 hit.
    HAMAPiMF_00600. CH60.
    InterProiIPR018370. Chaperonin_Cpn60_CS.
    IPR001844. Chaprnin_Cpn60.
    IPR002423. Cpn60/TCP-1.
    IPR027409. GroEL-like_apical_dom.
    IPR027413. GROEL-like_equatorial.
    [Graphical view]
    PANTHERiPTHR11353. PTHR11353. 1 hit.
    PfamiPF00118. Cpn60_TCP1. 1 hit.
    [Graphical view]
    PRINTSiPR00298. CHAPERONIN60.
    SUPFAMiSSF48592. SSF48592. 2 hits.
    SSF52029. SSF52029. 1 hit.
    TIGRFAMsiTIGR02348. GroEL. 1 hit.
    PROSITEiPS00296. CHAPERONINS_CPN60. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P25750-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAKDVKFGN EARIKMLRGV NVLADAVKVT LGPKGRNVVL DKSFGAPSIT    50
    KDGVSVAREI ELEDKFENMG AQMVKEVASK ANDAAGDGTT TATLLAQSIV 100
    NEGLKAVAAG MNPMDLKRGI DKAVISAVEE LKHLSVPCSD SKAITQVGTI 150
    SANADEKVGS LIAEAMEKVG NDGVITVEEG TGLQDELEVV KGMQFDRGYL 200
    SPYFINKPET GIVELENPYI LMADKKISNV REMLPILESV AKSGKPLLII 250
    SEDLEGEALA TLVVNSMRGI VKVAAVKAPG FGDRRKAMLQ DISILTGGSV 300
    ISEELAMELE KSTLEDLGQA KRVVISKDTT TIIGGVGEKH SIQSRISQIR 350
    QEIQEATSDY DKEKLNERLA KLSGGVAVLK VGAATEVEMK EKKARVEDAL 400
    HATRAAVEEG VVAGGGVALV RVAGKIADLR GQNEDQNVGI RVALRAMEAP 450
    LRQIVSNSGE EPSVVTNNVK DGKGNYGYNA ATDEYGDMID FGILDPTKVT 500
    RSALQYAASV AGLMITTECM VTDLPKEDKS SDSSSSPAGG MGGMGGMM 548
    Length:548
    Mass (Da):57,911
    Last modified:May 1, 1992 - v1
    Checksum:i9B33AE1E629E7592
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X61150 Genomic DNA. Translation: CAA43460.1.
    BA000003 Genomic DNA. Translation: BAB12746.1.
    RefSeqiNP_239860.1. NC_002528.1.

    Genome annotation databases

    EnsemblBacteriaiBAB12746; BAB12746; BAB12746.
    GeneIDi1109527.
    KEGGibuc:BU019.
    PATRICi21243542. VBIBucAph127364_0031.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X61150 Genomic DNA. Translation: CAA43460.1 .
    BA000003 Genomic DNA. Translation: BAB12746.1 .
    RefSeqi NP_239860.1. NC_002528.1.

    3D structure databases

    ProteinModelPortali P25750.
    SMRi P25750. Positions 2-526.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 107806.BU019.

    Proteomic databases

    PRIDEi P25750.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB12746 ; BAB12746 ; BAB12746 .
    GeneIDi 1109527.
    KEGGi buc:BU019.
    PATRICi 21243542. VBIBucAph127364_0031.

    Phylogenomic databases

    eggNOGi COG0459.
    HOGENOMi HOG000076290.
    KOi K04077.
    OMAi VLFGNDA.
    OrthoDBi EOG6JDWBZ.

    Enzyme and pathway databases

    BioCyci BAPH107806:GBZJ-19-MONOMER.

    Family and domain databases

    Gene3Di 1.10.560.10. 2 hits.
    3.50.7.10. 1 hit.
    HAMAPi MF_00600. CH60.
    InterProi IPR018370. Chaperonin_Cpn60_CS.
    IPR001844. Chaprnin_Cpn60.
    IPR002423. Cpn60/TCP-1.
    IPR027409. GroEL-like_apical_dom.
    IPR027413. GROEL-like_equatorial.
    [Graphical view ]
    PANTHERi PTHR11353. PTHR11353. 1 hit.
    Pfami PF00118. Cpn60_TCP1. 1 hit.
    [Graphical view ]
    PRINTSi PR00298. CHAPERONIN60.
    SUPFAMi SSF48592. SSF48592. 2 hits.
    SSF52029. SSF52029. 1 hit.
    TIGRFAMsi TIGR02348. GroEL. 1 hit.
    PROSITEi PS00296. CHAPERONINS_CPN60. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structures of chaperonins from an intracellular symbiont and their functional expression in Escherichia coli groE mutants."
      Ohtaka C., Nakamura H., Ishikawa H.
      J. Bacteriol. 174:1869-1874(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
      Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
      Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: APS.

    Entry informationi

    Entry nameiCH60_BUCAI
    AccessioniPrimary (citable) accession number: P25750
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1992
    Last sequence update: May 1, 1992
    Last modified: October 1, 2014
    This is version 97 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
      Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3