Reviewed, UniProtKB/Swiss-Prot P25749 (CH10_BUCAI)

Names and origin

Protein names

Recommended name:
    10 kDa chaperonin
Alternative name(s):
    Protein Cpn10
    groES protein

Gene names

Name:	groS
Synonyms:	groES, mopB, symS
Ordered Locus Names:	BU018

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]

Taxonomic identifier

118099 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	96 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. HAMAP MF_00580
Subunit structure	Heptamer of 7 subunits arranged in a ring By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the groES chaperonin family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein folding Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 96	96	10 kDa chaperonin HAMAP MF_00580		PRO_0000174712

Sequences

	Sequence		Length	Mass (Da)
	P25749-1 [UniParc]. Last modified May 1, 1992. Version 1. Checksum: 23D60F9E3DD40645	FASTA	96	10,244
	10 20 30 40 50 60 MKIRPLHDRV LVKRQEVESK SAGGIVLTGS AAGKSTRGTV TAVGKGRVLD NGDIKPLDVK 70 80 90 VGDVVIFNEG YGAKTEKIDN EELLILTESD ILAIVE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structures of chaperonins from an intracellular symbiont and their functional expression in Escherichia coli groE mutants." Ohtaka C., Nakamura H., Ishikawa H. J. Bacteriol. 174:1869-1874(1992) [PubMed: 1347769] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tokyo 1998.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X61150 Genomic DNA. Translation: CAA43459.1. BA000003 Genomic DNA. Translation: BAB12745.1.
RefSeq	NP_239859.1.
3D structure databases
SMR	P25749. Positions 1-96.
ModBase	Search...
Genome annotation databases
GeneID	1109526.
GenomeReviews	Gene locus BU018 in contig BA000003_GR.
KEGG	buc:BU018.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P25749.
OMA	SEKIDGE
Enzyme and pathway databases
BioCyc	BSP107806:BU018-MON.
Family and domain databases
HAMAP	MF_00580. [Tree]
InterPro	IPR020818. Chaperonin_Cpn10. IPR018369. Chaprnonin_Cpn10_CS. IPR001476. Chaprnonin_Cpn10_subgroup. IPR011032. GroES-like. [Graphical view]
Gene3D	G3DSA:2.30.33.40. Chaprnin_Cpn10. 1 hit.
PANTHER	PTHR10772. Chaprnin_Cpn10. 1 hit.
Pfam	PF00166. Cpn10. 1 hit. [Graphical view]
PRINTS	PR00297. CHAPERONIN10.
SMART	SM00883. Cpn10. 1 hit. [Graphical view]
PROSITE	PS00681. CHAPERONINS_CPN10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CH10_BUCAI

Accession

Primary (citable) accession number: P25749

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 1992
Last sequence update:	May 1, 1992
Last modified:	November 24, 2009
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)