P25749 (CH10_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
10 kDa chaperonin

Alternative name(s):
GroES protein
Protein Cpn10

Gene names

Name:	groS
Synonyms:	groES, mopB, symS
Ordered Locus Names:	BU018

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]

Taxonomic identifier

107806 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Acyrthosiphon pisum)

Protein attributes

Sequence length	96 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter By similarity. HAMAP-Rule MF_00580
Subunit structure	Heptamer of 7 subunits arranged in a ring By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GroES chaperonin family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 96	96	10 kDa chaperonin HAMAP-Rule MF_00580		PRO_0000174712

Sequences

	Sequence		Length	Mass (Da)
	P25749 [UniParc]. Last modified May 1, 1992. Version 1. Checksum: 23D60F9E3DD40645	FASTA	96	10,244
	10 20 30 40 50 60 MKIRPLHDRV LVKRQEVESK SAGGIVLTGS AAGKSTRGTV TAVGKGRVLD NGDIKPLDVK 70 80 90 VGDVVIFNEG YGAKTEKIDN EELLILTESD ILAIVE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structures of chaperonins from an intracellular symbiont and their functional expression in Escherichia coli groE mutants." Ohtaka C., Nakamura H., Ishikawa H. J. Bacteriol. 174:1869-1874(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: APS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X61150 Genomic DNA. Translation: CAA43459.1. BA000003 Genomic DNA. Translation: BAB12745.1.
RefSeq	NP_239859.1. NC_002528.1.
3D structure databases
ProteinModelPortal	P25749.
SMR	P25749. Positions 1-96.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAB12745; BAB12745; BAB12745.
GeneID	1109526.
KEGG	buc:BU018.
PATRIC	21243540. VBIBucAph127364_0030.
Phylogenomic databases
eggNOG	COG0234.
HOGENOM	HOG000133897.
KO	K04078.
OMA	GYGVKVE.
ProtClustDB	PRK00364.
Family and domain databases
Gene3D	2.30.33.40. 1 hit.
HAMAP	MF_00580. CH10.
InterPro	IPR020818. Chaperonin_Cpn10. IPR018369. Chaprnonin_Cpn10_CS. IPR011032. GroES-like. [Graphical view]
PANTHER	PTHR10772. PTHR10772. 1 hit.
Pfam	PF00166. Cpn10. 1 hit. [Graphical view]
PRINTS	PR00297. CHAPERONIN10.
SMART	SM00883. Cpn10. 1 hit. [Graphical view]
SUPFAM	SSF50129. GroES_like. 1 hit.
PROSITE	PS00681. CHAPERONINS_CPN10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CH10_BUCAI

Accession

Primary (citable) accession number: P25749

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 1992
Last sequence update:	May 1, 1992
Last modified:	May 1, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program