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Protein

UPF0056 membrane protein YhcE

Gene

ychE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11342-MONOMER.
ECOL316407:JW1229-MONOMER.

Protein family/group databases

TCDBi2.A.95.1.7. the 6tms neutral amino acid transporter (naat) family.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0056 membrane protein YhcE
Gene namesi
Name:ychE
Ordered Locus Names:b1242, JW1229
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11342. ychE.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei14 – 3421HelicalSequence analysisAdd
BLAST
Transmembranei54 – 7421HelicalSequence analysisAdd
BLAST
Transmembranei81 – 10121HelicalSequence analysisAdd
BLAST
Transmembranei120 – 14021HelicalSequence analysisAdd
BLAST
Transmembranei147 – 16721HelicalSequence analysisAdd
BLAST
Transmembranei189 – 20921HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 215215UPF0056 membrane protein YhcEPRO_0000156901Add
BLAST

Proteomic databases

PaxDbiP25743.

Interactioni

Protein-protein interaction databases

BioGridi4263225. 9 interactions.
STRINGi511145.b1242.

Structurei

3D structure databases

ProteinModelPortaliP25743.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0056 (MarC) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EZI. Bacteria.
COG2095. LUCA.
HOGENOMiHOG000112971.
InParanoidiP25743.
OMAiAIILWTS.
PhylomeDBiP25743.

Family and domain databases

InterProiIPR002771. Multi_antbiot-R_MarC.
[Graphical view]
PfamiPF01914. MarC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00427. TIGR00427. 1 hit.

Sequencei

Sequence statusi: Complete.

P25743-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQTFFDFPV YFKFFIGLFA LVNPVGIIPV FISMTSYQTA AARNKTNLTA
60 70 80 90 100
NLSVAIILWI SLFLGDTILQ LFGISIDSFR IAGGILVVTI AMSMISGKLG
110 120 130 140 150
EDKQNKQEKS ETAVRESIGV VPLALPLMAG PGAISSTIVW GTRYHSISYL
160 170 180 190 200
FGFFVAIALF ALCCWGLFRM APWLVRVLRQ TGINVITRIM GLLLMALGIE
210
FIVTGIKGIF PGLLN
Length:215
Mass (Da):23,521
Last modified:November 1, 1997 - v2
Checksum:i82679FE8E7C8B71E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59501 Genomic DNA. Translation: CAA42090.1.
U00096 Genomic DNA. Translation: AAC74324.1.
AP009048 Genomic DNA. Translation: BAA36122.2.
PIRiE64871.
RefSeqiNP_415758.1. NC_000913.3.
WP_000616554.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74324; AAC74324; b1242.
BAA36122; BAA36122; BAA36122.
GeneIDi945836.
KEGGiecj:JW1229.
eco:b1242.
PATRICi32117742. VBIEscCol129921_1291.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59501 Genomic DNA. Translation: CAA42090.1.
U00096 Genomic DNA. Translation: AAC74324.1.
AP009048 Genomic DNA. Translation: BAA36122.2.
PIRiE64871.
RefSeqiNP_415758.1. NC_000913.3.
WP_000616554.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP25743.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263225. 9 interactions.
STRINGi511145.b1242.

Protein family/group databases

TCDBi2.A.95.1.7. the 6tms neutral amino acid transporter (naat) family.

Proteomic databases

PaxDbiP25743.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74324; AAC74324; b1242.
BAA36122; BAA36122; BAA36122.
GeneIDi945836.
KEGGiecj:JW1229.
eco:b1242.
PATRICi32117742. VBIEscCol129921_1291.

Organism-specific databases

EchoBASEiEB1318.
EcoGeneiEG11342. ychE.

Phylogenomic databases

eggNOGiENOG4105EZI. Bacteria.
COG2095. LUCA.
HOGENOMiHOG000112971.
InParanoidiP25743.
OMAiAIILWTS.
PhylomeDBiP25743.

Enzyme and pathway databases

BioCyciEcoCyc:EG11342-MONOMER.
ECOL316407:JW1229-MONOMER.

Miscellaneous databases

PROiP25743.

Family and domain databases

InterProiIPR002771. Multi_antbiot-R_MarC.
[Graphical view]
PfamiPF01914. MarC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00427. TIGR00427. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYCHE_ECOLI
AccessioniPrimary (citable) accession number: P25743
Secondary accession number(s): P76025, Q9R7N0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: November 1, 1997
Last modified: September 7, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.