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Protein

Lipopolysaccharide core heptosyltransferase RfaQ

Gene

rfaQ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes heptose transfer to the lipopolysaccharide core. It transfers a heptose, called heptose(III), to the heptose(II) of the inner core (By similarity).By similarity

Pathwayi: LPS core biosynthesis

This protein is involved in the pathway LPS core biosynthesis, which is part of Bacterial outer membrane biogenesis.
View all proteins of this organism that are known to be involved in the pathway LPS core biosynthesis and in Bacterial outer membrane biogenesis.

GO - Molecular functioni

GO - Biological processi

  • lipopolysaccharide core region biosynthetic process Source: EcoCyc

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processLipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11341-MONOMER
MetaCyc:EG11341-MONOMER
UniPathwayiUPA00958

Protein family/group databases

CAZyiGT9 Glycosyltransferase Family 9

Names & Taxonomyi

Protein namesi
Recommended name:
Lipopolysaccharide core heptosyltransferase RfaQ (EC:2.-.-.-)
Gene namesi
Name:rfaQ
Synonyms:waaQ
Ordered Locus Names:b3632, JW3607
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11341 rfaQ

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002072651 – 344Lipopolysaccharide core heptosyltransferase RfaQAdd BLAST344

Proteomic databases

PaxDbiP25742
PRIDEiP25742

Interactioni

Protein-protein interaction databases

BioGridi4259595, 230 interactors
DIPiDIP-10675N
IntActiP25742, 2 interactors
STRINGi316385.ECDH10B_3814

Structurei

3D structure databases

ProteinModelPortaliP25742
SMRiP25742
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 9 family.Curated

Phylogenomic databases

eggNOGiENOG4105DKP Bacteria
COG0859 LUCA
HOGENOMiHOG000010798
InParanoidiP25742
KOiK02849
OMAiDALLNMQ
PhylomeDBiP25742

Family and domain databases

InterProiView protein in InterPro
IPR002201 Glyco_trans_9
IPR011916 LipoPS_heptosylTferase-III
PfamiView protein in Pfam
PF01075 Glyco_transf_9, 1 hit
TIGRFAMsiTIGR02201 heptsyl_trn_III, 1 hit

Sequencei

Sequence statusi: Complete.

P25742-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYHGDMLLT TPVISTLKQN YPDAKIDMLL YQDTIPILSE NPEINALYGI
60 70 80 90 100
SNKGAGTFDK IKNVLSLIKT LRANNYDLVI NLTDQWMVAL LVRCLPARMK
110 120 130 140 150
ISQLYGHRQH GIWKKSFTHL APIHGTHIVE RNLSVLEPLG ITDFYTDTTM
160 170 180 190 200
SYAEDCWKKM RRELDALGVK DHYVVIQPTA RQIFKCWDND KFSKVIDALQ
210 220 230 240 250
QRGYQVVLTC GPSADDLACV DEIARGCETK PITGLAGKTR FPELGALIDH
260 270 280 290 300
AVLFIGVDSA PGHIAAAVKT PVISLFGATD HVFWRPWTEN IIQFWAGNYQ
310 320 330 340
KMPTRHELDR NKKYLSVIPA EDVIAATEKL LPEDAPSADR NAQL
Length:344
Mass (Da):38,731
Last modified:June 1, 1994 - v2
Checksum:i1C788368BE46404A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M80599 Genomic DNA Translation: AAA24081.1
M86305 Genomic DNA Translation: AAA03744.1
U00039 Genomic DNA Translation: AAB18609.1
U00096 Genomic DNA Translation: AAC76656.1
AP009048 Genomic DNA Translation: BAE77660.1
PIRiS27560
RefSeqiNP_418089.1, NC_000913.3

Genome annotation databases

EnsemblBacteriaiAAC76656; AAC76656; b3632
BAE77660; BAE77660; BAE77660
GeneIDi948155
KEGGiecj:JW3607
eco:b3632
PATRICifig|511145.12.peg.3752

Similar proteinsi

Entry informationi

Entry nameiRFAQ_ECOLI
AccessioniPrimary (citable) accession number: P25742
Secondary accession number(s): Q2M7U6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: June 1, 1994
Last modified: March 28, 2018
This is version 133 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health