SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P25699

- FRI_PHAVU

UniProt

P25699 - FRI_PHAVU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Ferritin, chloroplastic
Gene
PFE
Organism
Phaseolus vulgaris (Kidney bean) (French bean)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation By similarity.

Catalytic activityi

4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi99 – 991Iron 1 By similarity
Metal bindingi134 – 1341Iron 1 By similarity
Metal bindingi134 – 1341Iron 2 By similarity
Metal bindingi137 – 1371Iron 1 By similarity
Metal bindingi183 – 1831Iron 2 By similarity
Metal bindingi217 – 2171Iron 2 By similarity

GO - Molecular functioni

  1. ferric iron binding Source: InterPro
  2. ferroxidase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. cellular iron ion homeostasis Source: UniProtKB-KW
  2. iron ion transport Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Iron storage

Keywords - Ligandi

Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ferritin, chloroplastic (EC:1.16.3.1)
Gene namesi
Name:PFE
OrganismiPhaseolus vulgaris (Kidney bean) (French bean)
Taxonomic identifieri3885 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaePhaseolus

Subcellular locationi

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 4848Chloroplast
Add
BLAST
Chaini49 – 254206Ferritin, chloroplastic
PRO_0000008863Add
BLAST

Proteomic databases

ProMEXiP25699.

Interactioni

Subunit structurei

Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited By similarity.

Structurei

3D structure databases

ProteinModelPortaliP25699.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini82 – 235154Ferritin-like diiron
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni49 – 8133Extension peptide (EP)
Add
BLAST

Sequence similaritiesi

Belongs to the ferritin family.

Keywords - Domaini

Transit peptide

Family and domain databases

Gene3Di1.20.1260.10. 1 hit.
InterProiIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERiPTHR11431. PTHR11431. 1 hit.
PfamiPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS00540. FERRITIN_1. 1 hit.
PS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P25699-1 [UniParc]FASTAAdd to Basket

« Hide

MALAPSKVSP FSGFSLSDGV GAVRNPTCSV SLSFLNKKVG SRNLGVSAST    50
VPLTGVIFEP FEEVKKEELA VPTAGQVSLA RQYYADECES AINEQINVEY 100
NASYVYHSLF AYFDRDNVAL KGFARFFKES SEEEREHAEK LMKYQNTRGG 150
RVVLHPIKNV PSEFEHVEKG DALYAMELAL SLEKLVNEKL RSVHSVADRN 200
KDPQLADFIE SEFLSEQVEA IKKISEYVAQ LRMVGKGHGV WHFDQSLLHD 250
GHAA 254
Length:254
Mass (Da):28,304
Last modified:May 1, 1992 - v1
Checksum:i60B0E974D3F4435F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X58274 mRNA. Translation: CAA41213.1. Sequence problems.
PIRiS17426. FRFBH.
RefSeqiXP_007140214.1. XM_007140152.1.

Genome annotation databases

GeneIDi18622338.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X58274 mRNA. Translation: CAA41213.1 . Sequence problems.
PIRi S17426. FRFBH.
RefSeqi XP_007140214.1. XM_007140152.1.

3D structure databases

ProteinModelPortali P25699.
ModBasei Search...

Proteomic databases

ProMEXi P25699.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 18622338.

Family and domain databases

Gene3Di 1.20.1260.10. 1 hit.
InterProi IPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
[Graphical view ]
PANTHERi PTHR11431. PTHR11431. 1 hit.
Pfami PF00210. Ferritin. 1 hit.
[Graphical view ]
SUPFAMi SSF47240. SSF47240. 1 hit.
PROSITEi PS00540. FERRITIN_1. 1 hit.
PS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The structure of a Phaseolus vulgaris cDNA encoding the iron storage protein ferritin."
    Spence M.J., Henzl M.T., Lammers P.J.
    Plant Mol. Biol. 17:499-504(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Tendergreen.
    Tissue: Seed.

Entry informationi

Entry nameiFRI_PHAVU
AccessioniPrimary (citable) accession number: P25699
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi