ID   YCY0_YEAST              Reviewed;         182 AA.
AC   P25654; D6VR90;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   27-MAR-2024, entry version 139.
DE   RecName: Full=UPF0587 protein YCR090C;
GN   OrderedLocusNames=YCR090C; ORFNames=YCR1104, YCR90C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1523889; DOI=10.1002/yea.320080708;
RA   Wilson C., Grisanti P., Frontali L.;
RT   "The complete sequence of a 6146 bp fragment of Saccharomyces cerevisiae
RT   chromosome III contains two new open reading frames.";
RL   Yeast 8:569-575(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=1574125; DOI=10.1038/357038a0;
RA   Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M.,
RA   Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G.,
RA   Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A.,
RA   Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M., Carcano C.,
RA   Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M.,
RA   Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C.,
RA   Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F.,
RA   Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C.,
RA   Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E.,
RA   Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P.,
RA   Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J.,
RA   Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P.,
RA   Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M.,
RA   Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P.,
RA   Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G.,
RA   Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E.,
RA   Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F.,
RA   Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L.,
RA   Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J.,
RA   Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M.,
RA   Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A.,
RA   Richterich P., Roberts A.B., Rodriguez F., Sanz E.,
RA   Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J.,
RA   Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I.,
RA   Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M.,
RA   Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M.,
RA   Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D.,
RA   Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K.,
RA   Sgouros J.G.;
RT   "The complete DNA sequence of yeast chromosome III.";
RL   Nature 357:38-46(1992).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [5]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
CC   -!- DOMAIN: Requires a bound zinc ion for normal folding and solubility.
CC       {ECO:0000250|UniProtKB:Q9NWV4}.
CC   -!- MISCELLANEOUS: Present with 3970 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
CC   -!- SIMILARITY: Belongs to the UPF0587 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X59720; CAA42255.1; -; Genomic_DNA.
DR   EMBL; AY558154; AAS56480.1; -; Genomic_DNA.
DR   EMBL; BK006937; DAA07559.1; -; Genomic_DNA.
DR   PIR; S19506; S19506.
DR   RefSeq; NP_010014.1; NM_001178796.1.
DR   AlphaFoldDB; P25654; -.
DR   SMR; P25654; -.
DR   BioGRID; 31062; 258.
DR   MINT; P25654; -.
DR   STRING; 4932.YCR090C; -.
DR   MaxQB; P25654; -.
DR   PaxDb; 4932-YCR090C; -.
DR   PeptideAtlas; P25654; -.
DR   EnsemblFungi; YCR090C_mRNA; YCR090C; YCR090C.
DR   GeneID; 850452; -.
DR   KEGG; sce:YCR090C; -.
DR   AGR; SGD:S000000686; -.
DR   SGD; S000000686; YCR090C.
DR   VEuPathDB; FungiDB:YCR090C; -.
DR   eggNOG; KOG1296; Eukaryota.
DR   GeneTree; ENSGT00390000001523; -.
DR   HOGENOM; CLU_114688_0_0_1; -.
DR   InParanoid; P25654; -.
DR   OMA; TAHFVWR; -.
DR   OrthoDB; 5490773at2759; -.
DR   BioCyc; YEAST:G3O-29384-MONOMER; -.
DR   BioGRID-ORCS; 850452; 0 hits in 10 CRISPR screens.
DR   PRO; PR:P25654; -.
DR   Proteomes; UP000002311; Chromosome III.
DR   RNAct; P25654; Protein.
DR   GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR   GO; GO:0005634; C:nucleus; HDA:SGD.
DR   GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR   InterPro; IPR008584; CXXC_Zn-binding_euk.
DR   PANTHER; PTHR12857:SF0; CXXC MOTIF CONTAINING ZINC BINDING PROTEIN; 1.
DR   PANTHER; PTHR12857; UNCHARACTERIZED; 1.
DR   Pfam; PF05907; CXXC_Zn-b_euk; 1.
DR   SUPFAM; SSF141678; MAL13P1.257-like; 1.
PE   1: Evidence at protein level;
KW   Metal-binding; Reference proteome; Zinc.
FT   CHAIN           1..182
FT                   /note="UPF0587 protein YCR090C"
FT                   /id="PRO_0000202580"
FT   BINDING         36
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT   BINDING         39
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT   BINDING         70
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT   BINDING         73
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
SQ   SEQUENCE   182 AA;  20704 MW;  BF03D05179E74483 CRC64;
     MPLFLVLKAT LSENVTKVSI ENTNESRAEF AFDLQCTSCR ELHDSKVIIN TFEEYAMPAS
     KGTASFLMKC KFCSKELSVN LCAFEDEYLT DQSDDKWAKI KDVRKKHGLS KVKEDSFIPL
     SLDCRGCELI KFYPDTITFE VSLSSGKVMS CQLEDNEWYD YDDNLGEEVT MTDFSSSIIK
     GK
//