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Protein

54S ribosomal protein IMG1, mitochondrial

Gene

IMG1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:25609543, PubMed:24675956). bL19m is essential for respiration (PubMed:8771712).2 Publications1 Publication

Miscellaneous

Present with 4150 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29357-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein IMG1, mitochondrial
Alternative name(s):
Integrity of mitochondrial genome protein 1
Mitochondrial large ribosomal subunit protein bL19m1 Publication
PetCR46
Gene namesi
Name:IMG1
Synonyms:PETCR46
Ordered Locus Names:YCR046C
ORF Names:YCR46C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:YCR046C
SGDiS000000642 IMG1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 16MitochondrionSequence analysisAdd BLAST16
ChainiPRO_000003047717 – 16954S ribosomal protein IMG1, mitochondrialAdd BLAST153

Proteomic databases

MaxQBiP25626
PaxDbiP25626
PRIDEiP25626

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins.2 Publications

Protein-protein interaction databases

BioGridi31028, 270 interactors
DIPiDIP-4995N
IntActiP25626, 50 interactors
MINTiP25626
STRINGi4932.YCR046C

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20M1-169[»]
5MRCelectron microscopy3.25M16-166[»]
5MREelectron microscopy3.75M16-166[»]
5MRFelectron microscopy4.97M16-166[»]
ProteinModelPortaliP25626
SMRiP25626
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000248530
InParanoidiP25626
OMAiIPVYPPV
OrthoDBiEOG092C4M2I

Family and domain databases

Gene3Di2.30.30.790, 1 hit
InterProiView protein in InterPro
IPR038657 L19_sf
IPR001857 Ribosomal_L19
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR15680 PTHR15680, 1 hit
PfamiView protein in Pfam
PF01245 Ribosomal_L19, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P25626-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWSRNVRLLG SWTRSYMVPA TKRKTIPVYP PVQRIASSQI MKQVALSEIE
60 70 80 90 100
SLDPGAVKRK LISKKNKDRL KAGDVVRIVY DSSKCSYDTF VGYILSIDRK
110 120 130 140 150
QLVQDASLLL RNQIAKTAVE IRVPLFSPLI ERIDLLTPHV SSRQRNKHYY
160
IRGTRLDVGD LEAGLRRKK
Length:169
Mass (Da):19,394
Last modified:May 1, 1992 - v1
Checksum:i56C79944D654FA21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA Translation: CAA42294.1
AY692869 Genomic DNA Translation: AAT92888.1
BK006937 Genomic DNA Translation: DAA07524.1
PIRiS19459
RefSeqiNP_009975.1, NM_001178760.1

Genome annotation databases

EnsemblFungiiCAA42294; CAA42294; CAA42294
YCR046C; YCR046C; YCR046C
GeneIDi850413
KEGGisce:YCR046C

Similar proteinsi

Entry informationi

Entry nameiIMG1_YEAST
AccessioniPrimary (citable) accession number: P25626
Secondary accession number(s): D6VR55
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: May 23, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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