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Protein

54S ribosomal protein IMG1, mitochondrial

Gene

IMG1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:25609543, PubMed:24675956). bL19m is essential for respiration (PubMed:8771712).2 Publications1 Publication

Miscellaneous

Present with 4150 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29357-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein IMG1, mitochondrial
Alternative name(s):
Integrity of mitochondrial genome protein 1
Mitochondrial large ribosomal subunit protein bL19m1 Publication
PetCR46
Gene namesi
Name:IMG1
Synonyms:PETCR46
Ordered Locus Names:YCR046C
ORF Names:YCR46C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:YCR046C.
SGDiS000000642. IMG1.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: SGD

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 16MitochondrionSequence analysisAdd BLAST16
ChainiPRO_000003047717 – 16954S ribosomal protein IMG1, mitochondrialAdd BLAST153

Proteomic databases

MaxQBiP25626.
PRIDEiP25626.

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins.2 Publications

Protein-protein interaction databases

BioGridi31028. 268 interactors.
DIPiDIP-4995N.
IntActiP25626. 33 interactors.
MINTiMINT-571589.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20M1-169[»]
5MRCelectron microscopy3.25M16-166[»]
5MREelectron microscopy3.75M16-166[»]
5MRFelectron microscopy4.97M16-166[»]
ProteinModelPortaliP25626.
SMRiP25626.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000248530.
InParanoidiP25626.
OMAiIASSQIM.
OrthoDBiEOG092C4M2I.

Family and domain databases

InterProiView protein in InterPro
IPR001857. Ribosomal_L19.
IPR008991. Translation_prot_SH3-like.
PANTHERiPTHR15680. PTHR15680. 1 hit.
PfamiView protein in Pfam
PF01245. Ribosomal_L19. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P25626-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWSRNVRLLG SWTRSYMVPA TKRKTIPVYP PVQRIASSQI MKQVALSEIE
60 70 80 90 100
SLDPGAVKRK LISKKNKDRL KAGDVVRIVY DSSKCSYDTF VGYILSIDRK
110 120 130 140 150
QLVQDASLLL RNQIAKTAVE IRVPLFSPLI ERIDLLTPHV SSRQRNKHYY
160
IRGTRLDVGD LEAGLRRKK
Length:169
Mass (Da):19,394
Last modified:May 1, 1992 - v1
Checksum:i56C79944D654FA21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAA42294.1.
AY692869 Genomic DNA. Translation: AAT92888.1.
BK006937 Genomic DNA. Translation: DAA07524.1.
PIRiS19459.
RefSeqiNP_009975.1. NM_001178760.1.

Genome annotation databases

EnsemblFungiiCAA42294; CAA42294; CAA42294.
YCR046C; YCR046C; YCR046C.
GeneIDi850413.
KEGGisce:YCR046C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAA42294.1.
AY692869 Genomic DNA. Translation: AAT92888.1.
BK006937 Genomic DNA. Translation: DAA07524.1.
PIRiS19459.
RefSeqiNP_009975.1. NM_001178760.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20M1-169[»]
5MRCelectron microscopy3.25M16-166[»]
5MREelectron microscopy3.75M16-166[»]
5MRFelectron microscopy4.97M16-166[»]
ProteinModelPortaliP25626.
SMRiP25626.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31028. 268 interactors.
DIPiDIP-4995N.
IntActiP25626. 33 interactors.
MINTiMINT-571589.

Proteomic databases

MaxQBiP25626.
PRIDEiP25626.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAA42294; CAA42294; CAA42294.
YCR046C; YCR046C; YCR046C.
GeneIDi850413.
KEGGisce:YCR046C.

Organism-specific databases

EuPathDBiFungiDB:YCR046C.
SGDiS000000642. IMG1.

Phylogenomic databases

HOGENOMiHOG000248530.
InParanoidiP25626.
OMAiIASSQIM.
OrthoDBiEOG092C4M2I.

Enzyme and pathway databases

BioCyciYEAST:G3O-29357-MONOMER.

Miscellaneous databases

PROiPR:P25626.

Family and domain databases

InterProiView protein in InterPro
IPR001857. Ribosomal_L19.
IPR008991. Translation_prot_SH3-like.
PANTHERiPTHR15680. PTHR15680. 1 hit.
PfamiView protein in Pfam
PF01245. Ribosomal_L19. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiIMG1_YEAST
AccessioniPrimary (citable) accession number: P25626
Secondary accession number(s): D6VR55
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: April 12, 2017
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.