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Protein

54S ribosomal protein IMG1, mitochondrial

Gene

IMG1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Essential for respiration.1 Publication

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29357-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein IMG1, mitochondrial
Alternative name(s):
Integrity of mitochondrial genome protein 1
PetCR46
Gene namesi
Name:IMG1
Synonyms:PETCR46
Ordered Locus Names:YCR046C
ORF Names:YCR46C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome III

Organism-specific databases

CYGDiYCR046c.
EuPathDBiFungiDB:YCR046C.
SGDiS000000642. IMG1.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 1616MitochondrionSequence AnalysisAdd
BLAST
Chaini17 – 16915354S ribosomal protein IMG1, mitochondrialPRO_0000030477Add
BLAST

Proteomic databases

MaxQBiP25626.
PaxDbiP25626.

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).1 Publication

Protein-protein interaction databases

BioGridi31028. 44 interactions.
DIPiDIP-4995N.
IntActiP25626. 33 interactions.
MINTiMINT-571589.
STRINGi4932.YCR046C.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20M1-169[»]
ProteinModelPortaliP25626.
SMRiP25626. Positions 39-160.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L19P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0335.
HOGENOMiHOG000248530.
InParanoidiP25626.
OMAiIASSQIM.
OrthoDBiEOG75TMPH.

Family and domain databases

InterProiIPR001857. Ribosomal_L19.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERiPTHR15680. PTHR15680. 1 hit.
PfamiPF01245. Ribosomal_L19. 1 hit.
[Graphical view]
SUPFAMiSSF50104. SSF50104. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P25626-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWSRNVRLLG SWTRSYMVPA TKRKTIPVYP PVQRIASSQI MKQVALSEIE
60 70 80 90 100
SLDPGAVKRK LISKKNKDRL KAGDVVRIVY DSSKCSYDTF VGYILSIDRK
110 120 130 140 150
QLVQDASLLL RNQIAKTAVE IRVPLFSPLI ERIDLLTPHV SSRQRNKHYY
160
IRGTRLDVGD LEAGLRRKK
Length:169
Mass (Da):19,394
Last modified:May 1, 1992 - v1
Checksum:i56C79944D654FA21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAA42294.1.
AY692869 Genomic DNA. Translation: AAT92888.1.
BK006937 Genomic DNA. Translation: DAA07524.1.
PIRiS19459.
RefSeqiNP_009975.1. NM_001178760.1.

Genome annotation databases

EnsemblFungiiYCR046C; YCR046C; YCR046C.
GeneIDi850413.
KEGGisce:YCR046C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAA42294.1.
AY692869 Genomic DNA. Translation: AAT92888.1.
BK006937 Genomic DNA. Translation: DAA07524.1.
PIRiS19459.
RefSeqiNP_009975.1. NM_001178760.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20M1-169[»]
ProteinModelPortaliP25626.
SMRiP25626. Positions 39-160.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31028. 44 interactions.
DIPiDIP-4995N.
IntActiP25626. 33 interactions.
MINTiMINT-571589.
STRINGi4932.YCR046C.

Proteomic databases

MaxQBiP25626.
PaxDbiP25626.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYCR046C; YCR046C; YCR046C.
GeneIDi850413.
KEGGisce:YCR046C.

Organism-specific databases

CYGDiYCR046c.
EuPathDBiFungiDB:YCR046C.
SGDiS000000642. IMG1.

Phylogenomic databases

eggNOGiCOG0335.
HOGENOMiHOG000248530.
InParanoidiP25626.
OMAiIASSQIM.
OrthoDBiEOG75TMPH.

Enzyme and pathway databases

BioCyciYEAST:G3O-29357-MONOMER.

Miscellaneous databases

NextBioi965968.
PROiP25626.

Family and domain databases

InterProiIPR001857. Ribosomal_L19.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERiPTHR15680. PTHR15680. 1 hit.
PfamiPF01245. Ribosomal_L19. 1 hit.
[Graphical view]
SUPFAMiSSF50104. SSF50104. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The complete DNA sequence of yeast chromosome III."
    Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M.
    , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
    Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "PetCR46, a gene which is essential for respiration and integrity of the mitochondrial genome."
    Coppee J.-Y., Rieger K.-J., Kaniak A., di Rago J.-P., Groudinsky O., Slonimski P.P.
    Yeast 12:577-582(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  5. "Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components."
    Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K.
    Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL LARGE COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  7. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  8. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.

Entry informationi

Entry nameiIMG1_YEAST
AccessioniPrimary (citable) accession number: P25626
Secondary accession number(s): D6VR55
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: June 24, 2015
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 4150 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.