Reviewed, UniProtKB/Swiss-Prot P25617 (YCQ6_YEAST)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein YCR016W

Gene names

Ordered Locus Names:	YCR016W
ORF Names:	YCR16W

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	290 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Miscellaneous

Present with 1850 molecules/cell in log phase SD medium. Ref.4

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	nucleolus Inferred from direct assay. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
PRP40	P33203	1	EBI-375711,EBI-701
SSM4	P40318	1	EBI-375711,EBI-18208

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 290	290	Uncharacterized protein YCR016W		PRO_0000202563
Regions
	Compositional bias	52 – 98	47	Lys-rich
Amino acid modifications
	Modified residue	21	1	Phosphoserine Ref.5

Sequences

	Sequence		Length	Mass (Da)
	P25617-1 [UniParc]. Last modified October 10, 2003. Version 2. Checksum: 55A72BB7C7172C63	FASTA	290	33,593
	10 20 30 40 50 60 MSENHVPAWK RIALKRQTIS SGDESKEKGQ SNLIDDDPLN ITTHLSTGNL TKKEKKRIIN 70 80 90 100 110 120 GESKSSTKKG KRVSKPGTKK KEKLSKDEKN SKKNKILKDQ LRYLIEFFRT KSESKFPTGI 130 140 150 160 170 180 LELESVKENY GDSLIKDEPS ESGVVEVWKF SKQKQNWLIK HFFNLDEIPS VYNDLLLLYF 190 200 210 220 230 240 RDLQGKSKEE LISKCKGKLK QWNDYVEDQE TKIKALIAED KASEPINGEE KEEGEKDGNA 250 260 270 280 290 EQGKQKEVQD EQEEVQMPNK ELVQRSLKLL EIWKNDDSEQ IELKNFFVDV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete DNA sequence of yeast chromosome III." Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M. , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G. Nature 357:38-46(1992) [PubMed: 1574125] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	Valles G., Volckaerts G. Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION TO 212.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]	"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H. Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed: 17563356] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X59720 Genomic DNA. Translation: CAC42971.1. AY692612 Genomic DNA. Translation: AAT92631.1.
PIR	S19426.
RefSeq	NP_009942.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:4766N.
IntAct	P25617. 4 interactions.
Proteomic databases
PeptideAtlas	P25617.
PRIDE	P25617.
Genome annotation databases
Ensembl	YCR016W. Saccharomyces cerevisiae. [Contig view]
GeneID	850375.
GenomeReviews	Gene locus YCR016W in contig X59720_GR.
KEGG	sce:YCR016W.
NMPDR	fig|4932.3.peg.665.
Organism-specific databases
CYGD	YCR016w.
SGD	S000000609. YCR016W.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	P25617.
OMA	P25617. DQLRYLI.
Gene expression databases
ArrayExpress	P25617.
GermOnline	YCR016W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR019327. DUF2373. [Graphical view]
Pfam	PF10180. DUF2373. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	965872.

Entry information

Entry name

YCQ6_YEAST

Accession

Primary (citable) accession number: P25617
Secondary accession number(s): Q8NIM2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 1992
Last sequence update:	October 10, 2003
Last modified:	June 16, 2009
This is version 56 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)