Reviewed, UniProtKB/Swiss-Prot P25612 (AAD3_YEAST)

Names and origin

Protein names

Recommended name:
    Putative aryl-alcohol dehydrogenase AAD3
    EC=1.1.1.-

Gene names

Name:	AAD3
Ordered Locus Names:	YCR107W

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the aldo/keto reductase 2 family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW response to toxin Inferred from expression pattern. Source: SGD
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 363	363	Putative aryl-alcohol dehydrogenase AAD3		PRO_0000070365

Sequences

	Sequence		Length	Mass (Da)
	P25612-1 [UniParc]. Last modified May 1, 1992. Version 1. Checksum: FFC74519895671DC	FASTA	363	40,911
	10 20 30 40 50 60 MIGSASDSSS KLGRLRFLSE TAAIKVSPLI LGEVSYDGAR SDFLKSMNKN RAFELLDTFY 70 80 90 100 110 120 EAGGNFIDAA NNCQNEQSEE WIGEWIQSRR LRDQIVIATK FIKSDKKYKA GESNTANYCG 130 140 150 160 170 180 NHKRSLHVSV RDSLRKLQTD WIDILYVHWW DYMSSIEEFM DSLHILVQQG KVLYLGVSDT 190 200 210 220 230 240 PAWVVSAANY YATSYGKTPF SIYQGKWNVL NRDFERDIIP MARHFGMALA PWDVMGGGRF 250 260 270 280 290 300 QSKKAMEERR KNGEGIRSFV GASEQTDAEI KISEALAKIA EEHGTESVTA IAIAYVRSKA 310 320 330 340 350 360 KNFFPSVEGG KIEDLKENIK ALSIDLTPDN IKYLESIVPF DIGFPNNFIV LNSLTQKYGT NNV

References

[1]

"The complete DNA sequence of yeast chromosome III." Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M. , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G. Nature 357:38-46(1992) [PubMed: 1574125] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X59720 Genomic DNA. Translation: CAA42239.1.
PIR	S19419.
RefSeq	NP_010032.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-2610N.
IntAct	P25612. 2 interactions.
STRING	P25612.
Genome annotation databases
Ensembl	YCR107W; YCR107W; YCR107W; Saccharomyces cerevisiae. [Genome view]
GeneID	850471.
KEGG	sce:YCR107W.
NMPDR	fig|4932.3.peg.762.
Organism-specific databases
CYGD	YCR107w.
SGD	S000000704. AAD3.
Phylogenomic databases
HOGENOM	HBG605727.
OMA	GESNTAN.
OrthoDB	EOG9XWHFX.
Gene expression databases
ArrayExpress	P25612.
Genevestigator	P25612.
GermOnline	YCR107W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001395. Aldo/ket_red. [Graphical view]
Gene3D	G3DSA:3.20.20.100. Aldo/ket_red. 1 hit.
PANTHER	PTHR11732. Aldo/ket_red. 1 hit.
Pfam	PF00248. Aldo_ket_red. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	966122.

Entry information

Entry name

AAD3_YEAST

Accession

Primary (citable) accession number: P25612

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 1992
Last sequence update:	May 1, 1992
Last modified:	December 15, 2009
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)