P25603 (CWH36_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative uncharacterized protein CWH36

Gene names

Name:	CWH36
Ordered Locus Names:	YCL007C
ORF Names:	YCL7C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	130 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Caution

Product of a dubious gene prediction. Almost completely overlaps VMA9. Was originally (Ref.2) thought to function in calcofluor white resistance, hence the name CWH36, but this phenotype was later (Ref.3) attributed to the overlapping gene VMA9.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 130	130	Putative uncharacterized protein CWH36		PRO_0000079617

Sequences

	Sequence		Length	Mass (Da)
	P25603 [UniParc]. Last modified May 1, 1992. Version 1. Checksum: 9820E892291BD709	FASTA	130	15,469
	10 20 30 40 50 60 MELAKERNGP HQKHHGQCQN HCTSPNTVRQ NKTNKLLLVK KKGKLVIWRH IVKKMLHIRL 70 80 90 100 110 120 VVLWSHYPEQ HGHGTNHYEY TNNSIAKLDA QRVSRRRRKK REAERRDYDT YKLLITLCSL 130 LFVGPLFLKV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete DNA sequence of yeast chromosome III." Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M. , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G. Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"A new approach for isolating cell wall mutants in Saccharomyces cerevisiae by screening for hypersensitivity to calcofluor white." Ram A.F., Wolters A., Ten Hoopen R., Klis F.M. Yeast 10:1019-1030(1994) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[3]	"Genome-wide analysis of iron-dependent growth reveals a novel yeast gene required for vacuolar acidification." Davis-Kaplan S.R., McVey Ward D., Shiflett S.L., Kaplan J. J. Biol. Chem. 279:4322-4329(2004) [PubMed] [Europe PMC] [Abstract] Cited for: REVISION OF FUNCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X59720 Genomic DNA. Translation: CAA42352.1.
PIR	S19409.
3D structure databases
ProteinModelPortal	P25603.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-5350N.
IntAct	P25603. 1 interaction.
MINT	MINT-512062.
STRING	4932.YCL007C.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YCL007C; YCL007C; YCL007C.
Organism-specific databases
SGD	S000000513. CWH36.
Gene expression databases
Genevestigator	P25603.
GermOnline	YCL007C. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

CWH36_YEAST

Accession

Primary (citable) accession number: P25603

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 1992
Last sequence update:	May 1, 1992
Last modified:	April 3, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program